Projects funded by the NCN


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332 projects found matching your search criteria :

  1. Small-molecule inhibitors of protein aggregation and ER stress as a novel strategy against neurodegeneration in the cour...

    Call: PRELUDIUM BIS 3 , Panel: NZ5

    Principal investigator: prof. Ireneusz Jacek Majsterek

    Uniwersytet Medyczny w Łodzi

  2. New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Anna Katarzyna Florczak-Substyk

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  3. Function of DNA methylation and CNV-type polymorphisms of genes encoding metalloproteinase and their tissue inhibitors i...

    Call: OPUS 2 , Panel: NZ5

    Principal investigator: dr Edyta Magdalena Majorczyk

    Politechnika Opolska, Wydział Wychowania Fizycznego i Fizjoterapii

  4. Lipidic liquid-crystalline nanomaterials for reconstitution and physico-chemical studies of membrane proteins

    Call: OPUS 22 , Panel: ST4

    Principal investigator: prof. Renata Bilewicz

    Uniwersytet Warszawski, Wydział Chemii

  5. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  6. Search for Inhibitors of Human δ1-Pyrroline-5-Carboxylate Reductase 1 (PYCR1) as Lead Molecules for the Development of N...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  7. The structures, biochemistry, physiology, and evolution of bacterial α2-macroglobulins from the human periodontopathogen...

    Call: SONATA BIS 11 , Panel: NZ1

    Principal investigator: dr Mirosław Książek

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  8. RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Mikołaj Czajkowski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  9. Research on the influence of medicines of the angiotensin-converting enzyme inhibitors (ACEI) group on the choroidal and...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Jowita Zwolska

    Uniwersytet Przyrodniczy w Lublinie, Wydział Medycyny Weterynaryjnej

  10. Heterocyclization of benzenoid ansamycins core as useful strategy for designing anticancer agents

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Natalia Anna Skrzypczak

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  11. Novel combination therapies of pulmonary arterial hypertension targeting blockade of peripheral cannabinoid CB1 receptor...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Barbara Malinowska

    Uniwersytet Medyczny w Białymstoku

  12. Pharmacological potential of mistletoe (Viscum album L.) in the prevention of central nervous system disorders.

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Anna Szurpnicka

    Narodowy Instytut Leków

  13. New type of analogs and conjugates of folic acid with potential therapeutic applicaton in treatment of hormone-dependent...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Olga Ciupak

    Politechnika Gdańska, Wydział Chemiczny

  14. The role of glycosylation of structural proteins in the life cycle of SARS-CoV-2 coronavirus.

    Call: OPUS 21 , Panel: NZ6

    Principal investigator: dr hab. Ewelina Król

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  15. Effect of SSR 504734, a selective glycine transporter type 1 inhibitor, on seizure activity and therapeutic efficacy of ...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Piotr Wiktor Wlaź

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  16. The study of adsorption mechanisms of N-benzenamino(boronphenyl)methylphosphonic acids on different metal surfaces

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: dr Natalia Anna Piergies

    Uniwersytet Jagielloński, Wydział Chemii

  17. An influence of lipoproteins on fibrinolysis and pleiotropic effect of proprotein convertase subtilisin/kexin type 9 (PC...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Magdalena Teresa Kopytek

    Krakowski Szpital Specjalistyczny im. Jana Pawła II

  18. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  19. Synthetic epidermal growth factor receptor inhibitor conjugated with nobel metal nanoparticles as a potential drug for t...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Shaoshan Mai

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

  20. The SAR analysis and synthesis of complex, small molecule PD-1/PD-L1 interaction antagonists

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Magdalena Maria Żarnik

    Uniwersytet Jagielloński, Wydział Chemii

  21. Selective inhibitors of γ-aminobutyric acid (GABA) transporter subtype 3 (GAT3) as a new pharmacological tools and a cha...

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: dr Dawid Marcin Panek

    Uniwersytet Jagielloński, Collegium Medicum

  22. Aging-associated, specific pathomechanisms of endothelial dysfunction in sepsis: pathway analysis and experimental thera...

    Call: CHIST-ERA2020 , Panel: NZ7

    Principal investigator: prof. Stefan Karol Chłopicki

    Uniwersytet Jagielloński

  23. Single cell multi-omics in defining how specific oncogenic alterations shape the immune microenvironment and responses t...

    Call: OPUS 20 , Panel: NZ4

    Principal investigator: prof. Bożena Kamińska-Kaczmarek

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  24. Cell-to-cell transmission of SARS-CoV2 virus

    Call: PRELUDIUM BIS 2 , Panel: NZ6

    Principal investigator: prof. Krystyna Maria Bieńkowska-Szewczyk

    Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

  25. Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Adam Kazimierz Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  26. Comparison of the mechanism of action of valproic acid and levetiracetam as histone deacetylase inhibitors in ovarian ca...

    Call: PRELUDIUM 2 , Panel: NZ7

    Principal investigator: Patrycja Katarzyna Kwiecińska

    Uniwersytet Jagielloński, Wydział Biologii i Nauk o Ziemi

  27. Design of high selective and safe juvenile hormone epoxide hydrolases inhibitors targeting selected pests based on the c...

    Call: OPUS 20 , Panel: ST4

    Principal investigator: dr hab. Artur Wiktor Góra

    Politechnika Śląska, Centrum Biotechnologii

  28. Iron chelators as tyrosine kinase inhibitors - a new strategy for the treatment of glioblastoma multiforme

    Call: PRELUDIUM BIS 2 , Panel: NZ5

    Principal investigator: dr hab. Anna Dominika Mrozek-Wilczkiewicz

    Uniwersytet Śląski w Katowicach, Wydział Nauk Ścisłych i Technicznych

  29. Novel dual CYP17A1 and AKR1C3 inhibitors for studying the mechanism of resistance in prostate cancer

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Tomasz Marcin Wróbel

    Uniwersytet Medyczny w Lublinie

  30. Cell-based high-throughput screening for small-molecule compounds diminishing molecular markers of pathogenesis in myoto...

    Call: OPUS 20 , Panel: NZ3

    Principal investigator: dr hab. Marzena Wojciechowska

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  31. A novel approach based on the optimized multidrug combination for glioblastoma treatment.

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: prof. Małgorzata Kucińska

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  32. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Ewa Maria Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

  33. Changes in lipid metabolism of resistant to BRAF/MEK inhibitors human melanoma cells associated with the presence of adi...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Aleksandra Simiczyjew

    Uniwersytet Wrocławski, Wydział Biotechnologii

  34. Defining the interplay between SLPI and the IL-1 family cytokines in the immune response

    Call: SONATA 16 , Panel: NZ6

    Principal investigator: dr Ewa Małgorzata Oleszycka

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  35. Modulation of ATP production using glycolysis inhibitors in cancer cells monitored by novel biosensing systems based on ...

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Katarzyna Cecylia Ratajczak

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

  36. Role of cereal leaf beetle – associated bacteria in the adaptation of their insect host to the insecticides and protease...

    Call: PRELUDIUM 19 , Panel: NZ9

    Principal investigator: Beata Wielkopolan

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  37. Exploring the allosteric regulation of the SARS CoV-2 hydrolases using methyl-TROSY NMR spectroscopy - in search of nove...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wiktor Adam Koźmiński

    Uniwersytet Warszawski, Wydział Chemii

  38. DNA polymerase θ as a novel therapeutic target in personalized anticancer therapy

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Tomasz Adam Śliwiński

    Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

  39. Structure optimization of the PD-1/PD-L1 inhibitors based on the terphenyl scaffold

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: dr Damian Muszak

    Uniwersytet Jagielloński, Wydział Chemii

  40. Epigenetic regulation of expression of genes involved in extracellular matrix remodeling and angiogenesis during develop...

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: dr Radosław Bernard Maksym

    Warszawski Uniwersytet Medyczny, I Wydział Lekarski

  41. Dual CBR1-AKR1C3 inhibitors as a new approach to improve effectiveness and safety of anthracycline therapy.

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Marek Andrzej Jamrozik

    Uniwersytet Jagielloński, Collegium Medicum

  42. Novel L-asparaginases as potential therapeutic agents and antimicrobial targets: structural and functional studies of en...

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Mariusz Jaskólski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  43. New steroid sulfatase inhibitors based on 1,2,4-oxadiazole sulfamate derivatives

    Call: PRELUDIUM 19 , Panel: NZ7

    Principal investigator: Karol Andrzej Biernacki

    Politechnika Gdańska, Wydział Chemiczny

  44. Inhalable polymeric delivery systems of antibiotics and quorum sensing inhibitors for the treatment of respiratory infec...

    Call: OPUS 18 , Panel: ST5

    Principal investigator: prof. Elżbieta Pamuła

    Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

  45. Molecular mechanisms of interplay between RORγ/RORγT receptors and cyclin-dependent kinase inhibitor (AT7519). Analysis ...

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Kaja Urszula Karaś

    Instytut Biologii Medycznej Polskiej Akademii Nauk

  46. SufA bacterial protease inhibitors as potential diagnostic tools and antibacterial agents.

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Ewa Magdalena Burchacka

    Politechnika Wrocławska

  47. Inhibitors of serine proteases as regulators of dendritic cell function.

    Call: MAESTRO 1 , Panel: NZ5

    Principal investigator: prof. Joanna Cichy

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  48. Development of a three-dimensional in vitro model for studying the mechanisms of immunostimulatory activity of PD-1/PD-L...

    Call: PRELUDIUM 18 , Panel: NZ5

    Principal investigator: Justyna Natalia Kocik-Król

    Uniwersytet Jagielloński, Wydział Chemii

  49. Molecular mechanisms, signal transduction and inhibition of PEBP1-15LOX protein complex triggering the ferroptotic cell ...

    Call: SONATA 15 , Panel: ST4

    Principal investigator: dr hab. Karolina Anna Mikulska-Rumińska

    Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  50. A new approach of vision restoration based on modified Rabies virus tracing technique

    Call: SONATA BIS 9 , Panel: NZ5

    Principal investigator: dr hab. Andrzej Tomasz Foik

    Instytut Chemii Fizycznej Polskiej Akademii Nauk