Significance of the TNF, TNFR1, TNFR2, TRAF1, TRAF6 and TACE gene polymorphisms, clinical parameters and biomarkers for the efficacy of the treatment with TNF alfa inhibitors in patients with rheumatoid arthritis
2011/01/B/NZ5/05367
Keywords
Descriptors
- NZ5_7: Leczenie chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej, Wydział Lekarski
Voivodeship: dolnośląskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 8
Call
OPUS 1 – announced on 2011-03-15
- Amount awarded
- 279 600 PLN
- Project start date
- 2011-12-01
- Project end date
- 2014-11-30
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (3)
-
IL-17A, IL-17F and IL-23R gene polymorphisms in rheumatoid arthritis
- Authors:
- Bogunia-Kubik K, Świerkot J, Malak A, Wysoczańska B, Nowak B, Białowąs K, Gębura K, Korman L, Wiland P
- Academic press:
- Arch Immunol Ther Exp (year: 2015, volume: 63 (3), pages: 215-221), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s00005-014-0319-5 – link to the publication
-
Analysis of associations between polymorphisms within genes codingfor tumour necrosis factor (TNF)-alpha and TNF receptors andresponsiveness to TNF-alpha blockers in patients with rheumatoidarthritis
- Authors:
- Jerzy Swierkot, Katarzyna Bogunia-Kubik, Beata Nowak, Katarzyna Bialowas,Lucyna Korman, Katarzyna Gebura, Katarzyna Kolossa, Slawomir Jeka, Piotr Wilanda
- Academic press:
- Joint Bone Spine (year: 2014, volume: in press, pages: in press), Publisher: Elsevier Mason France
- Status:
- Published
- DOI:
- 10.1016/j.jbspin.2014.08.006 – link to the publication
-
Significance of association of HLA-C and HLA-E with psoriatic arthritis
- Authors:
- Renata Sokolik, Katarzyna Gebura , Milena Iwaszko, Jerzy Swierkot, Lucyna Korman, Piotr Wiland , Katarzyna Bogunia-Kubik
- Academic press:
- Human Immunology (year: 2014, volume: 75, pages: 1188-1191), Publisher: ELSEVIER
- Status:
- Published
- DOI:
- 10.1016/j.humimm.2014.10.005 – link to the publication
Articles in post-conference publications (4)
-
Wpływ polimorfizmu czynnika martwicy nowotworów TNF -308 G>A na skuteczność leczenia chorych na reumatoidalne zapalenie stawów inhibitorami TNF-alfa
- Authors:
- Świerkot J,Bogunia -Kubik K, Nowak B, Kolossa K, Białowąs K, Gębura K, Korman L, Jeka S, Wiland P
- Conference:
- IX Środkowoeuropejski Kongres Reumatologiczny CECR 2012 (year: 2012, pages: 72), Publisher: Termedia
- Date:
- conference 01-03.09. 2012
- Status:
- Published
-
ANALYSIS OF ASSOCIATIONS BETWEEN TUMOR NECROSIS FACTOR-ALPHA (TNFA -308 G>A, TNFA -238 G>A, TNFA -857 C>T) AND TNF RECEPTORS (TNFRA 36 A>G, TNFRB 676 T>G) GENE POLYMORPHISMS STATUS AND RESPONSIVENESS TO TNF-A BLOCKERS IN RHEUMATOID ARTHRITIS
- Authors:
- J. Swierkot, K. Bogunia-Kubik, B. Nowak, K. Bialowas, L. Korman, K. Gebura, K. Kolossa, S. Jeka, P. Wiland
- Conference:
- Annual European Congress of Rheumatology 2013 (year: 2013, pages: 386), Publisher: BMJ/Journals
- Date:
- conference czerwiec 2013
- Status:
- Published
-
Czy oznaczenie polimorfizmów genów kodujących TNF-alfa i jego receptory może pomóc w personalizacji terapii chorych na RZS?
- Authors:
- J Świerkot, K. Bogunia- Kubik, B. Nowak, K. Białowąs, L.Korman, K.Gębura, K.Kolossa, S.Jeka, P. Wiland
- Conference:
- IV Krajowe Spotkania Reumatologiczne (year: 2013, pages: 38), Publisher: Skolamed
- Date:
- conference 12-14.09.2013
- Status:
- Published
-
TNF-alfa, TNF receptor, HLA-E and NKG2A gene polymorphisms and response to anti TNF-alfa treatment in rheumatoid arthritis
- Authors:
- Swierkot J, Iwaszko M, Gebura K, Nowak B, Korman L, Kolossa K, Jeka S, Wiland P, Bogunia-Kubik K
- Conference:
- Annual European Congress of Rheumatology EULAR 2014 (year: 2014, pages: 87-88), Publisher: BMJ
- Date:
- conference 11-14.06.2014
- Status:
- Published