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Information on the principal investigator and host institution

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Keywords

Equipment

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Effect of aliskiren, a renin inhibitor, on the anticonvulsant activity of antiepileptic drugs in three seizure tests in mice

2013/09/B/NZ7/04010

Keywords:

aliskiren antiepileptic drugs drug interactions seizures mice

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Medycyny Wsi im. Witolda Chodźki

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Krzysztof Łukawski 

Number of co-investigators in the project: 3

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 232 000 PLN

Project start date (Y-m-d): 2014-02-17

Project end date (Y-m-d): 2017-08-16

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Wytrząsarka Velp Vortex Classic (1 045 PLN)
  2. Generator elektrowstrząsów 57800 (Ugo Basile, Comerio, Italy) (24 000 PLN)
  3. Urządzenie typu "rota-rod" dla myszy 47600 (Ugo Basile, Comerio, Italy) (24 000 PLN)
  4. Wytrząsarka kołyskowa DRS-12 z platformą (2 952 PLN)
  5. Para elektrod rogówkowych 57800-003 (Ugo Basile, Comerio, Italy) (2 000 PLN)
  6. Chłodziarko-zamrażarka Samsung RB31FERNDSS (2 152 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Effect of aliskiren, a direct renin inhibitor, on the protective action of antiepileptic drugs against pentylenetetrazole-induced clonic seizures in mice
    Authors:
    Łukawski K, Raszewski G, Czuczwar SJ
    Academic press:
    Fundamental and Clinical Pharmacology (rok: 2019, tom: 33, strony: 191-198), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/fcp.12421 - link to the publication
  2. Interactions of aliskiren, a direct renin inhibitor, with antiepileptic drugs in the test of maximal electroshock in mice
    Authors:
    Łukawski K, Raszewski G, Czuczwar SJ
    Academic press:
    European Journal of Pharmacology (rok: 2018, tom: 819, strony: 108-113), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2017.11.037. - link to the publication
  3. Exploring the latest avenues for antiepileptic drug discovery and development
    Authors:
    Łukawski K, Gryta P, Łuszczki J, Czuczwar SJ
    Academic press:
    Expert Opinion On Drug Discovery (rok: 2016, tom: 11, strony: 369-382), Wydawca: Taylor & Francis Group
    Status:
    Published
    DOI:
    10.1517/17460441.2016.1154840 - link to the publication

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