Projects funded by the NCN
Synthesis and analysis of potential furin inhibitors in the development of the new therapeutic strategies against viral and bacterial diseases
2012/07/N/ST5/01998
Keywords:
furin proprotein convertases avian influenza H5N1
Descriptors:
- ST5_16:
- NZ1_2: Biochemistry
- ST5_23:
Panel:
ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering
Host institution :
Uniwersytet Gdański, Wydział Chemii
woj. pomorskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 2
Call: PRELUDIUM 4 - announced on 2012-09-15
Amount awarded: 100 000 PLN
Project start date (Y-m-d): 2013-07-25
Project end date (Y-m-d): 2015-07-24
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- kompresor do mikrofalowego synteatora peptydów (firmy CEM) (10 000 PLN)
- Membranowa pompa próżniowa (15 000 PLN)
- kolumna analityczna Jupiter C18.
- przedkolumna SecurityGuard Cartridges.
- kolumna semipreparatywna Jupiter C18.
Information in the final report
- Publication in academic press/journals (1)
- Articles in post-conference publications (1)
- Design and structure-activity relationship of a potent furin inhibitor derived from influenza hemagglutininAuthors:Monika A. Lewandowska-Goch, Anna Kwiatkowska, Teresa Łepek, Kevin Ly, Pauline Navals, Hugo Gagnon, Yves Dory, Adam Prahl and Robert DayAcademic press:ACS Medicinal Chemistry Letters (rok: 2021, tom: brak, strony: brak), Wydawca: American Chemical SocietyStatus:PublishedDOI:10.1021/acsmedchemlett.0c00386 - link to the publication
- Structural Determinants of Furin Inhibitors Derived from Influenza HemagglutininAuthors:Monika Lewandowska-Goch, Anna Kwiatkowska, Teresa Łepek, Adam Prahl and Robert DayConference:American Peptide Symposium (rok: 2015, ), Wydawca: American Peptide SocietyData:konferencja 20-25.06.2015Status:Published