Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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In vitro and in vivo studies on iminosugars as inhibitors of the biofilm formation by various bacteria pathogenic for humans

2018/31/B/NZ6/02443

Keywords:

bacteria biofilm iminosugars

Descriptors:

  • NZ6_4: Bacteriology
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Piotr Heczko 

Number of co-investigators in the project: 10

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 796 600 PLN

Project start date (Y-m-d): 2019-08-01

Project end date (Y-m-d): 2024-07-31

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. PDIA, an Iminosugar Compound with a Wide Biofilm Inhibitory Spectrum Covering Both Gram-Positive and Gram-Negative Human Bacterial Pathogens
    Authors:
    Kozień, Ł.; Gallienne, E.; Martin, O.; Front, S.; Strus, M.; Heczko, P.
    Academic press:
    Microorganisms (rok: 2022, tom: 10, strony: 1222), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/microorganisms10061222 - link to the publication
  2. Coagulase-Negative Staphylococci Contained in Gut Microbiota as a Primary Source of Sepsis in Low- and Very Low Birth Weight Neonates
    Authors:
    Edyta Golińska, Magdalena Strus, Anna Tomusiak-Plebanek, Grażyna Więcek, Łucja Kozień, Ryszard Lauterbach, Dorota Pawlik, Beata Rzepecka-Węglarz, Jolanta Kędzierska, Małgorzata Dorycka, Piotr B. Heczko
    Academic press:
    Journal of Clinical Medicine (rok: 2020, tom: 9(8), strony: 2517), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm9082517 - link to the publication
  3. Effect of a Short-Time Probiotic Supplementation on the Abundance of the Main Constituents of the Gut Microbiota of Term Newborns Delivered by Cesarean Section—A Randomized, Prospective, Controlled Clinical Trial
    Authors:
    Joanna Hurkala, Ryszard Lauterbach, Renata Radziszewska, Magdalena Strus, Piotr Heczko
    Academic press:
    Nutrients (rok: 2020, tom: 12(10), strony: 3128), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu12103128 - link to the publication
  4. Neonate Bloodstream Infections in Organization for Economic Cooperation and Development Countries: An Update on Epidemiology and Prevention
    Authors:
    Jadwiga Wójkowska-Mach, Agnieszka Chmielarczyk, Magdalena Strus, Ryszard Lauterbach, Piotr Heczko
    Academic press:
    Journal of Clinical Medicine (rok: 2019, tom: 8(10), strony: 1750), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm8101750 - link to the publication

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