Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of the immunomodulatory activity of cefazolin as a potential inhibitor of proinflammatory cytokines which bind to the common receptor gamma (CD132), the perspectives of autoimmune diseases treatment.

2014/13/N/NZ7/00258

Keywords:

common receptor gamma autoimmune diseases rheumatoid arthritis cefazolin

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_12: Prevention of human diseases

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Nauki o Zdrowiu z Oddziałem Pielęgniarstwa, Oddziałem Zdrowia Publicznego i Oddziałem Dietetyki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Barbara Żyżyńska-Granica 

Number of co-investigators in the project: 2

Call: PRELUDIUM 7 - announced on 2014-03-17

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2015-02-25

Project end date (Y-m-d): 2018-02-24

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. Pharmacophore guided discovery of small-molecule interleukin 15 inhibitors.
    Authors:
    Barbara Żyżyńska-Granica, Bartosz Trzaskowski, Szymon Niewieczerzał, Sławomir Filipek, Oliwia Zegrocka-Stendel, Małgorzata Dutkiewicz, Piotr Krzeczy nski, Magdalena Kowalewska, Katarzyna Koziak
    Academic press:
    European Journal of Medicinal Chemistry (rok: 2017, tom: 136, strony: 543-547), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejmech.2017.05.034 - link to the publication