Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Novel polyelectrolytes as potential inhibitors of HSV-1 virus - synthesis, properties and mechanism of action

2014/13/B/ST5/04510

Keywords:

herpes simplex virus polyelectrolytes receptor quantum dots specyficzne przeciwciała

Descriptors:

  • ST5_21:
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maria Nowakowska 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 988 400 PLN

Project start date (Y-m-d): 2015-06-03

Project end date (Y-m-d): 2018-12-02

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mała waga Langmuira z wyposażeniem (250 000 PLN)
  2. Sprzęt komputerowy.
  3. Zasilacz awaryjny UPS (2 600 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (1)
  1. Highly Effective and Safe Polymeric Inhibitors of Herpes Simplex Virus in Vitro and in Vivo
    Authors:
    Magdalena Pachota, Katarzyna Kłysik-Trzciańska, Aleksandra Synowiec, Shotaro Yukioka, Shin-Ichi Yusa, Mateusz Zając, Barbara Zawilinska, Tomasz Dzieciątkowski, Krzysztof Szczubialka, Krzysztof Pyrc, and Maria Nowakowska
    Academic press:
    ACS Appl. Mater. Interfaces (rok: 2019, tom: 11, strony: 26745-26752), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsami.9b10302 - link to the publication
  2. Inhibition of Herpes Simplex Viruses by Cationic Dextran Derivatives
    Authors:
    Magdalena Pachota, Katarzyna Klysik, Aleksandra Synowiec, Justyna Ciejka, Krzysztof Szczubiałka, Krzysztof Pyrć, Maria Nowakowska
    Academic press:
    Journal of Medicinal Chemistry (rok: 2017, tom: 60, strony: 8620-8630), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jmedchem.7b01189 - link to the publication
  3. Cat flu: Broad spectrum polymeric antivirals
    Authors:
    Aleksandra Synowiec, Irma Gryniuk, Magdalena Pachota, Łukasz Strzelec, Olga Roman, Katarzyna Kłysik-Trzciańska, Mateusz Zając, Inga Drebot, Katarzyna Gula, Aleksandra Andruchowicz, Zenon Rajfur, Krzysztof Szczubiałka, Maria Nowakowska, Krzysztof Pyrc
    Academic press:
    Antiviral Research (rok: 2019, tom: 170, strony: 104563 (1-13)), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.antiviral.2019.104563 - link to the publication
  4. In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
    Authors:
    Krzysztof Szczubiałka, Krzysztof Pyrć, Maria Nowakowska
    Academic press:
    RSC Advances (rok: 2016, tom: 6, strony: 1058-1075), Wydawca: The Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c5ra22896d - link to the publication
  5. Acyclovir in the Treatment of Herpes Viruses – A Review
    Authors:
    Katarzyna Klysik, Aneta Pietraszek, Anna Karewicz, Maria Nowakowska
    Academic press:
    Current Medicinal Chemistry (rok: 2018, tom: 25, strony: 45309), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/0929867325666180309105519 - link to the publication
  1. Antiviral polymers
    Authors:
    Krzysztof Szczubiałka, Justyna Ciejka, Aleksandra Milewska, Anna Gołda, Kamil Kamiński, Magdalena Wytrwał, Krzysztof Pyrć, Maria Nowakowska
    Conference:
    25th Biomaterials in Medicine and Veterinary Medicine Anniversary Conference (rok: 2016, ), Wydawca: Polish Society of Biomaterials and Faculty of Materials Science and Ceramics
    Data:
    konferencja 13-16 października 2016
    Status:
    Published

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