Projects funded by the NCN

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201 projects found matching your search criteria :

  1. Influence of modified maternal diet on the phenotype of offspring: behavioral and molecular correlations

    Call: ETIUDA 8 , Panel: NZ7

    Principal investigator: Kinga Eryka Gawlińska

    Instytut Farmakologii PAN

  2. Combined administration of muscarinic receptor antagonists and group II/III metabotropic glutamate (mGlu) receptor ligan...

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii PAN

  3. Neurochemical basis of antidepressive properties of psychedelics in rodent model of depression

    Call: OPUS 19 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  4. Molecular profiling of novel antipsychotic drug candidates

    Call: OPUS 20 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  5. The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treat...

    Call: OPUS 3 , Panel: NZ4

    Principal investigator: dr Joanna Solich

    Instytut Farmakologii PAN

  6. Effect of paroxetine and risperidone on the heterodimerization of dopamine D2 and serotonin 5-HT1A receptor in the conte...

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: dr Magdalena Anna Kolasa

    Instytut Farmakologii PAN

  7. Activation of endogenous pronociceptive mechanisms of opioid system as an important factors in the development of neurop...

    Call: MAESTRO 3 , Panel: NZ4

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii PAN

  8. The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

    Call: SONATA 4 , Panel: NZ4

    Principal investigator: dr Marta Ewa Kot

    Instytut Farmakologii PAN

  9. The role of the brain serotonergic system in the expression and activity of liver cytochrome P450.

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: dr Marta Anna Rysz

    Instytut Farmakologii PAN

  10. Research on influence of antidepressant drugs on serum and brain levels of neurotrophins in rats, affected by the time d...

    Call: OPUS 4 , Panel: NZ4

    Principal investigator: dr Maciej Sławomir Kuśmider

    Instytut Farmakologii PAN

  11. The role of chemokines in the pathogenesis of depression and molecular mechanism of action of antidepressants.

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  12. Effect of caffeine on neurotoxicity of methamphetamine and 3,4-methylenedioxymethamphetamine in the mouse brain.

    Call: PRELUDIUM 6 , Panel: NZ7

    Principal investigator: Anna Maria Górska

    Instytut Farmakologii PAN

  13. The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal r...

    Call: OPUS 6 , Panel: NZ4

    Principal investigator: prof. Grzegorz Władysław Hess

    Instytut Farmakologii PAN

  14. Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

    Call: SONATA 7 , Panel: NZ7

    Principal investigator: dr Katarzyna Małgorzata Stachowicz

    Instytut Farmakologii PAN

  15. Investigating the role of the focal adhesion kinase and its related signaling pathways in glucocorticoid- and stress-ind...

    Call: PRELUDIUM 20 , Panel: NZ4

    Principal investigator: Michał Józef Wilczkowski

    Instytut Farmakologii PAN

  16. Novel hope for diseased joints: a polymer-based treatment to promoteregenerative strategies for patients with osteoarthr...

    Call: PRELUDIUM 20 , Panel: NZ7

    Principal investigator: Marta Kędziora

    Instytut Farmakologii PAN

  17. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  18. Translational and interdisciplinary investigation of phenotypes of reinforcement sensitivity as predictors of the respon...

    Call: OPUS 22 , Panel: HS6

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  19. Early-life programming for neurodevelopmental disorders: search for a prodrome target within the vascular network in a r...

    Call: OPUS 23 , Panel: NZ4

    Principal investigator: prof. Małgorzata Maria Filip

    Instytut Farmakologii PAN

  20. The role of halogen bonding in interaction of ligands with SERT.

    Call: SONATA 11 , Panel: NZ7

    Principal investigator: dr Jakub Staroń

    Instytut Farmakologii PAN

  21. The evaluation of the efficacy of alpha7 nicotinic acetylcholine receptor ligands in rat models of autism

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Anna Nikiforuk

    Instytut Farmakologii PAN

  22. Impact of early-life stress on maturation, permeability of blood brain-barrier and neuroinflammatory processes activatio...

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Anna Katarzyna Solarz

    Instytut Farmakologii PAN

  23. Sensitivity to negative feedback as a cognitive biomarker of depression in an animal model

    Call: OPUS 12 , Panel: NZ4

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  24. Modulation of inflammatory processes using new agonists of the formyl peptide receptors ALX/FPR2 as a new therapeutic st...

    Call: HARMONIA 9 , Panel: NZ7

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  25. New strategies in neuropathic pain pharmacotherapy based on the modulation of the functions of chemokine receptors CCR2 ...

    Call: PRELUDIUM 15 , Panel: NZ7

    Principal investigator: dr Klaudia Kwiatkowski

    Instytut Farmakologii PAN

  26. Exploring new drug targets for efficacious therapy of neuropathic pain basing on the assessment and modulation of neuroi...

    Call: OPUS 2 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  27. Pharmacological evaluation of possible neuroprotective strategies in novel genetic mouse models of progressive neurodege...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr Grzegorz Kreiner

    Instytut Farmakologii PAN

  28. The role of glucocorticoids in the regulaton of neurodegenerative prosses

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Anna Jadwiga Kurek

    Instytut Farmakologii PAN

  29. The role of cognitive bias in individual vulnerability to to the transition from controlled use to uncontrolled abuse of...

    Call: OPUS 16 , Panel: NZ7

    Principal investigator: dr hab. Rafał Ryguła

    Instytut Farmakologii PAN

  30. Development of a comprehensive set of computational tools for the search of new ligands of particular receptor - case st...

    Call: OPUS 16 , Panel: NZ2

    Principal investigator: dr hab. Sabina Marta Podlewska

    Instytut Farmakologii PAN

  31. The role of epigenetic readers from BET family in the emergence and treatment of schizophrenia-like abnormalities in a n...

    Call: OPUS 16 , Panel: NZ4

    Principal investigator: prof. Marzena Małgorzata Maćkowiak

    Instytut Farmakologii PAN

  32. The influence of muscarinic acetylcholine receptors (M1, M4 and M5) and serotonergic 5-HT1A receptor modulation on cogni...

    Call: PRELUDIUM 16 , Panel: NZ7

    Principal investigator: dr Paulina Agnieszka Cieślik

    Instytut Farmakologii PAN

  33. Physical exercise as a natural mechanism inducing neuroregeneration. Search for the new protein markers and therapeutic ...

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Katarzyna Zofia Kuter-Nowak

    Instytut Farmakologii PAN

  34. In vivo effects, underlying signaling pathways and mechanism of action of ghrelin receptor agonist against pathological ...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Piotr Chmielarz

    Instytut Farmakologii PAN

  35. Fluorine substitution – a new algorithm for increasing biological activity

    Call: PRELUDIUM 18 , Panel: NZ7

    Principal investigator: Wojciech Pietruś

    Instytut Farmakologii PAN

  36. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist...

    Call: OPUS 9 , Panel: NZ7

    Principal investigator: prof. Mariusz Papp

    Instytut Farmakologii PAN

  37. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

    Call: HARMONIA 7 , Panel: NZ7

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  38. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola...

    Call: PRELUDIUM 10 , Panel: NZ7

    Principal investigator: Karolina Sylwia Podkowa

    Instytut Farmakologii PAN

  39. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa...

    Call: OPUS 11 , Panel: NZ4

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  40. Characterisation of the orbitofrontal cortex dopamine D1 and D2 receptors' influence on rat's cognitive flexibility and ...

    Call: PRELUDIUM 11 , Panel: NZ4

    Principal investigator: Michał Dariusz Rychlik

    Instytut Farmakologii PAN

  41. Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal...

    Call: PRELUDIUM 11 , Panel: NZ4

    Principal investigator: Joanna Ewa Sowa

    Instytut Farmakologii PAN

  42. Modulation of 5-HT7 receptor signaling as common mechanism involved in the long-lasting antidepressant effects of typica...

    Call: SONATA 20 , Panel: NZ7

    Principal investigator: dr Barbara Wanda Chruścicka-Smaga

    Instytut Farmakologii PAN

  43. NMR Spectroscopy as Molecular Language: A Deep Learning Approach to Bioactivity Prediction

    Call: PRELUDIUM 24 , Panel: NZ7

    Principal investigator: Arkadiusz Bogumił Leniak

    Instytut Farmakologii PAN

  44. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Teresa Potasiewicz

    Instytut Farmakologii PAN

  45. Neural substrates of decision making under risk and uncertainty: role of phasic activity of dopamine neurons

    Call: PRELUDIUM 8 , Panel: NZ4

    Principal investigator: Przemysław Eligiusz Cieślak

    Instytut Farmakologii PAN

  46. The role of kynurenine pathway in neurophatic pain in view of innovative treatment approaches

    Call: SONATA 9 , Panel: NZ4

    Principal investigator: dr Ewelina Joanna Rojewska

    Instytut Farmakologii PAN

  47. The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on pre...

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Iwona Magdalena Majcher-Maślanka

    Instytut Farmakologii PAN

  48. Dual histamine H3 and sigma-1 receptor ligands as novel pharmacological tools in the treatment of central nervous system...

    Call: SONATINA 4 , Panel: NZ7

    Principal investigator: dr Katarzyna Anna Szczepańska

    Instytut Farmakologii PAN

  49. Prenatal exposure to glucocorticoids as a risk factor for depression - the importance of epigenetic mechanisms in the br...

    Call: SONATA 16 , Panel: NZ7

    Principal investigator: dr Katarzyna Elżbieta Głombik

    Instytut Farmakologii PAN

  50. The effect of omega-3 fatty acid-enriched diet on the myelination impairment and the depression-like phenotype induced b...

    Call: SONATA 16 , Panel: NZ5

    Principal investigator: dr Irena Maria Smaga-Maślanka

    Instytut Farmakologii PAN

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