Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Glucocorticoid-induced alterations of astrocytic metabolism in stress-related disorders.

2011/03/B/NZ3/01683

Keywords:

astrocytes stress glucocorticoids

Descriptors:

  • NZ3_5: Molecular neurobiology
  • NZ4_11: Metabolism
  • NZ3_6: Cell neurobiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Ślęzak 

Number of co-investigators in the project: 6

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 781 571 PLN

Project start date (Y-m-d): 2012-08-21

Project end date (Y-m-d): 2016-02-20

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. laptop do analizy danych (4 000 PLN)
  2. system do warunkowania lękowego (60 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Behavioral and molecular alterations in mice resulting from chronic treatment with dexamethasone: relevance to depression
    Authors:
    Skupio Urszula, Tertil Magdalena, Sikora Magdalena, Gołda Sławomir, Wawrzczak-Bargieła Agnieszka, Przewłocki Ryszard
    Academic press:
    Neuroscience (rok: 2015, tom: 286, strony: 141-150), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2014.11.035 - link to the publication
  2. Glucocorticoid receptor signaling in astrocytes is required for aversive memory formation.
    Authors:
    Magdalena Tertil, Urszula Skupio, Justyna Barut, Valentyna Dubovyk, Agnieszka Wawrzczak-Bargiela, Zbigniew Soltys, Slawomir Golda, Lucja Kudla, Lucja Wiktorowska, Klaudia Szklarczyk, Michal Korostynski, Ryszard Przewlocki, Michal Slezak
    Academic press:
    Translational Psychiatry (rok: 2018, tom: 8(1), strony: 255), Wydawca: Springer Nature Ltd
    Status:
    Published
    DOI:
    10.1038/s41398-018-0300-x - link to the publication
  1. Acute and chronic administration of glucocorticoids affect expression of glucocorticoid receptor and target genes in astrocytes in vitro.
    Authors:
    Magdalena Tertil, Agnieszka Wawrzczak-Bargieła, Sławomir Gołda, Michał Ślęzak
    Conference:
    Neuronus 2014 IBRO & IRUN Neuroscience Forum (rok: 2014, ), Wydawca: www.neuronusforum.pl
    Data:
    konferencja 25-27 kwiecień 2014
    Status:
    Published
  2. Astrocyte-specific transcriptional response to glucocorticoid receptor stimulation - metabolic implications
    Authors:
    M. Tertil, S. Golda, A. Wawrzczak-Bargiela, M. Korostynski, M. Piechota, M. Slezak, R. Przewlocki
    Conference:
    XII European Meeting on Glial Cells in Health and Disease, Bilbao, Spain (rok: 2015, ), Wydawca: Wiley Periodicals, Inc.
    Data:
    konferencja 15-18 lipiec 2015
    Status:
    Published
  3. Molecular basis of astrocytic response to glucocorticoids: lentiviral vector-mediated RNA interference study
    Authors:
    Magdalena Tertil, Urszula Skupio, Agnieszka Wawrzczak-Bargieła, Sławomir Gołda, Michał Ślęzak, Ryszard Przewłocki
    Conference:
    Glia in Health & Disease (rok: 2014, ), Wydawca: Cold Spring Harbor Laboratory Meetings & Courses
    Data:
    konferencja 17-21 lipiec 2014
    Status:
    Published