Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

2012/05/N/NZ7/02110

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia
  • NZ1_2: Biochemia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Grzegorz Marek Satała

Number of co-investigators in the project: 2

Call

PRELUDIUM 3 – announced on 2012-03-15

Amount awarded
99 983 PLN
Project start date
2013-01-30
Project end date
2015-01-29
Project duration
24 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (2)

  1. Allosteric Inhibition of Serotonin 5-HT7 Receptors by Zinc Ions

    Authors:
    Grzegorz Satała, Beata Duszyńska, Tomasz Lenda, Gabriel Nowak, Andrzej J. Bojarski
    Academic press:
    Molecular Neurobiology (year: 2017, volume: wersja online, pages: 46036), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-017-0536-0 – link to the publication
  2. Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies

    Authors:
    Grzegorz Satała, Beata Duszyńska,Katarzyna Stachowicz, Anna Rafalo, Bartłomiej Pochwat, Christine Luckhart, Paul R. Albert, Mireille Daigle, Kenji F. Tanaka, René Hen, Tomasz Lenda, Gabriel Nowak, Andrzej J. Bojarski, Bernadeta Szewczyk
    Academic press:
    Molecular Neurobiology (year: 2016, volume: 53, pages: 6869-6881), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-015-9586-3 – link to the publication

Articles in post-conference publications (4)

  1. Identyfikacja modulacji allosterycznej w grupie receptorów serotoninowych GPCR.

    Authors:
    Grzegorz Satała, Tomasz Lenda, Beata Duszyńska, Andrzej J. Bojarski
    Conference:
    Wpływ Młodych Naukowców na Osiągnięcia Polskiej Nauki VIII Edycja (year: 2015, pages: 62), Publisher: CreativeTime
    Date:
    conference 28.03.2015
    Status:
    Published
  2. Mechanizm oddziaływania jonów cynku z wybranymi typami receptora serotoninowego.

    Authors:
    Grzegorz Satała, Tomasz Lenda, Beata Duszyńska, Andrzej J. Bojarski
    Conference:
    Dokonania Naukowe Doktorantów III Edycja (year: 2015, pages: 99), Publisher: CreativeTime
    Date:
    conference 18.04.2015
    Status:
    Published
  3. Badanie wpływu jonów cynku na receptory serotoninowe 5-HT7 metodami in vitro i in silico

    Authors:
    Grzegorz Satała, Stefan Mordalski ,Beata Duszyńska, Andrzej J. Bojarski
    Conference:
    II Ogólnopolskie Sympozjum Interdyscyplinarne Inter-Mix 2014 (year: 2014, pages: 78), Publisher: Klub Stypendystów Fundacji na rzecz Nauki Polskiej
    Date:
    conference 20-23.11.2014
    Status:
    Published
  4. Pharmacological characterization of zinc interaction with 5HT7

    Authors:
    Grzegorz Satała, Beata Duszyńska, Andrzej J. Bojarski
    Conference:
    VI Konwersatorium Chemii Medycznej, 18-20.09.2014, Lublin (year: 2014, pages: 153), Publisher: Polskie Towarzystwa Chemii Medycznej
    Date:
    conference 18-20.09.2014
    Status:
    Published

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