Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal raphe neurons in a model of chronic stress

2013/11/B/NZ4/04743

Keywords:

whole-cell patch-clamp electrophysiology serotonergic system corticosterone neuroplasticity

Descriptors:

  • NZ4_7: Neurophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Grzegorz Hess 

Number of co-investigators in the project: 4

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 670 000 PLN

Project start date (Y-m-d): 2014-07-08

Project end date (Y-m-d): 2017-07-07

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. mikroskop do badań elektrofizjologicznych na skrawkach (100 000 PLN)
  2. platforma ze stolikiem X-Y do mikroskopu do elektrofizjologii (50 000 PLN)
  3. stałoprądowa łaźnia wodna (4 243 PLN)
  4. oświetlacz do światła odbitego (6 999 PLN)

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (4)
  1. 5-HT7 receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin
    Authors:
    Kusek M, Sowa J, Kamińska K, Gołembiowska K, Tokarski K, Hess G
    Academic press:
    Frontiers in Cellular Neuroscience (rok: 2015, tom: 9, strony: 324), Wydawca: Frontiers Research Foundation
    Status:
    Published
    DOI:
    10.3389/fncel.2015.00324 - link to the publication
  1. 5-HT7 receptor modulates the GABAergic input to the rat dorsal raphe nucleus neurons
    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    10th FENS Forum of Neuroscience (rok: 2016, ), Wydawca: Federation of European Neuroscience Societies
    Data:
    konferencja 2-6.07.
    Status:
    Published
    DOI:
    link to the publication
  2. GABAergic input to the rat dorsal raphe nucleus neurons is modulated by the 5-HT7 receptor
    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    10th Conference. Electrophysiological techniques in bioelectricity research: from ion channels to neural networks (rok: 2016, ), Wydawca: Acta Neurobiologiae Experimentalis
    Data:
    konferencja 3-4. 06.
    Status:
    Published
  3. GABAergic transmission in the rat dorsal raphe nucleus is modulated by the 5-HT7 receptor
    Authors:
    Sowa J, Kusek M, Kamińska K, Gołembiowska K, Tokarski K, Hess G
    Conference:
    12th International Congress of the Polish Neuroscience Society (rok: 2015, ), Wydawca: Acta Neurobiologiae Experientalis
    Data:
    konferencja 6 - 8. 09. 2015 r.
    Status:
    Published
    DOI:
    link to the publication
  4. Repeated corticosterone administration attenuates the modulation of GABA-ergic transmission by 5-HT7 receptor in the rat dorsal raphe nucleus
    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    6th Mediterranean Neuroscience Society Conference (rok: 2017, ), Wydawca: Mediterranean Neuroscience Society
    Data:
    konferencja 12-15.06.
    Status:
    Published
    DOI:
    link to the publication

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