The influence of 5-HT7 and NMDA receptor ligands with possible antidepressive properties on the activity of rat dorsal raphe neurons in a model of chronic stress

2013/11/B/NZ4/04743

Keywords

Descriptors

  • NZ4_7: Neurofizjologia

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Grzegorz Władysław Hess

Number of co-investigators in the project: 4

Call

OPUS 6 – announced on 2013-09-16

Amount awarded
670 000 PLN
Project start date
2014-07-08
Project end date
2017-07-07
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. mikroskop do badań elektrofizjologicznych na skrawkach. Cost: 100 000 PLN
  2. oświetlacz do światła odbitego. Cost: 6 999 PLN
  3. platforma ze stolikiem X-Y do mikroskopu do elektrofizjologii. Cost: 50 000 PLN
  4. stałoprądowa łaźnia wodna. Cost: 4 243 PLN

Information in the final report

Publication in academic press/journals (1)

  1. 5-HT7 receptor modulates GABAergic transmission in the rat dorsal raphe nucleus and controls cortical release of serotonin

    Authors:
    Kusek M, Sowa J, Kamińska K, Gołembiowska K, Tokarski K, Hess G
    Academic press:
    Frontiers in Cellular Neuroscience (year: 2015, volume: 9, pages: 324), Publisher: Frontiers Research Foundation
    Status:
    Published
    DOI:
    10.3389/fncel.2015.00324 – link to the publication

Articles in post-conference publications (4)

  1. Repeated corticosterone administration attenuates the modulation of GABA-ergic transmission by 5-HT7 receptor in the rat dorsal raphe nucleus

    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    6th Mediterranean Neuroscience Society Conference (year: 2017, pages: P14.10), Publisher: Mediterranean Neuroscience Society
    Date:
    conference 12-15.06.
    Status:
    Published
  2. GABAergic input to the rat dorsal raphe nucleus neurons is modulated by the 5-HT7 receptor

    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    10th Conference. Electrophysiological techniques in bioelectricity research: from ion channels to neural networks (year: 2016, pages: VII), Publisher: Acta Neurobiologiae Experimentalis
    Date:
    conference 3-4. 06.
    Status:
    Published
  3. 5-HT7 receptor modulates the GABAergic input to the rat dorsal raphe nucleus neurons

    Authors:
    Sowa J, Kusek M, Tokarski K, Hess G
    Conference:
    10th FENS Forum of Neuroscience (year: 2016, pages: B021), Publisher: Federation of European Neuroscience Societies
    Date:
    conference 2-6.07.
    Status:
    Published
    DOI:
    link to the publication
  4. GABAergic transmission in the rat dorsal raphe nucleus is modulated by the 5-HT7 receptor

    Authors:
    Sowa J, Kusek M, Kamińska K, Gołembiowska K, Tokarski K, Hess G
    Conference:
    12th International Congress of the Polish Neuroscience Society (year: 2015, pages: S43), Publisher: Acta Neurobiologiae Experientalis
    Date:
    conference 6 - 8. 09. 2015 r.
    Status:
    Published
    DOI:
    link to the publication

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Graphic design and implementation: Jakub Piotrowski