Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of CRH-BP protein in the regulation of the hypothalamic-pituitary-adrenal axis after antidepressant drugs treatment.

2012/05/B/NZ4/02637

Keywords:

CRH-BP hypothalamic-pituitary-adrenal axis antidepressant drugs RT-PCR western blot ELISA

Descriptors:

  • NZ4_8: Neuroendocrinology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Joanna Solich 

Number of co-investigators in the project: 6

Call: OPUS 3 - announced on 2012-03-15

Amount awarded: 418 580 PLN

Project start date (Y-m-d): 2013-02-05

Project end date (Y-m-d): 2015-02-04

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Termocykler do przeprowadzenia reakcji łańcuchowej polimerazy w czasie rzeczywistym (Real Time PCR) (150 000 PLN)
  2. Wirówka.
  3. miniplatfoma kołysząca.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Norepinephrine transporter knock-out alters expression of the genes connected with antidepressant drugs action
    Authors:
    Solich J, Kolasa M, Kusmider M, Faron-Gorecka A, Pabian P, Zurawek D, Szafran-Pilch K, Dziedzicka-Wasylewska M.
    Academic press:
    Brain Research (rok: 2015, tom: 1594, strony: 284-92), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.055. - link to the publication
  1. Changes of the Crh-bp and Ucn mRNA expression after long-term antidepressant drugs administration
    Authors:
    J. Solich, M. Kolasa, A. Faron-Gorecka, M. Kusmider, K. Szafran, P. Pabian, D. Zurawek, M. Dziedzicka-Wasylewska
    Conference:
    9th FENS Forum of Neuroscience (rok: 2014, ), Wydawca: Federation of European Neuroscience Societies
    Data:
    konferencja 5 - 9 lipiec
    Status:
    Published
  2. Long-term administration of antidepressant drugs changes the expression of CRH-R1, CRH-R2 and CRH-BP mRNA
    Authors:
    Solich J., Kolasa M., Faron-Gorecka A., Zurawek D., Kusmider M., Pabian P., Szafran K., Dziedzicka-Wasylewska M.
    Conference:
    G Protein-Coupled Receptors: Structural Dynamics and Functional Implications (rok: 2014, ), Wydawca: Keystone Symposia on Molecular and Cellular Biology
    Data:
    konferencja 30 marzec - 4 kwiecień
    Status:
    Published

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