Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The molecular basis of stress-induced anxiety and affective disorders

2011/03/B/NZ2/02479

Keywords:

stress depression PTSD gene expression glucocorticoid receptor animal models

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ5_1: Etiology of human diseases

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Michał Korostyński 

Number of co-investigators in the project: 5

Call: OPUS 2 - announced on 2011-09-15

Amount awarded: 622 200 PLN

Project start date (Y-m-d): 2012-08-06

Project end date (Y-m-d): 2016-02-05

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. sprzęt komputerowy (4 500 PLN)
  2. Klatki dźwiękoszczelne z aplikacją szoku elektrycznego i oprogramowaniem (60 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Genotype-dependent consequences of traumatic stress in four inbred mouse strains
    Authors:
    Szklarczyk K, Korostynski M, Golda S, Solecki W, Przewlocki R
    Academic press:
    Genes, Brain and Behavior (rok: 2012, tom: 11 (8), strony: 977-985), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/j.1601-183X.2012.00850.x - link to the publication
  2. Opioid-dependent regulation of high and low fear responses in two inbred mouse strains
    Authors:
    Szklarczyk K., Korostynski M., Cieslak P., Wawrzczak-Bargiela A., Przewlocki R.
    Academic press:
    Behavioral Brain Research (rok: 2015, tom: 292, strony: 95-101), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbr.2015.06.001 - link to the publication
  3. Behavioral and molecular alterations in mice resulting from chronic treatment with dexamethasone: relevance to depression.
    Authors:
    Skupio U, Tertil M, Sikora M, Golda S, Wawrzczak-Bargiela A, Przewlocki R
    Academic press:
    Neuroscience (rok: 2015, tom: 286, strony: 141-150), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2014.11.035 - link to the publication
  4. Endogenous opioids regulate glucocorticoid-dependent stress coping strategies in mice
    Authors:
    Szklarczyk Klaudia, Korostynski Michal, Golda Slawomir, Piechota Marcin, Ficek Joanna, Przewlocki Ryszard
    Academic press:
    Neuroscience (rok: 2016, tom: 25;330, strony: 121-37), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2016.05.034. - link to the publication
  1. "From molecular markers to potential pharmacotherapeutic targets in stress-susceptible and resilient mouse strains"
    Authors:
    Szklarczyk K., Korostyński M., Gołda S., Smutek M., Cieślak P., Solecki W., Przewłocki R.
    Conference:
    FENS/IBRO School: Synaptic stress and pathogenesis of neuropsychiatric disorders (rok: 2013, ), Wydawca: FENS-IBRO European Neuroscience Schools Programme, Bertinoro, Italy
    Data:
    konferencja 24-30.03.2013
    Status:
    Published
  2. The dissection of stress-induced profile of gene expression between astrocytes and neurons.
    Authors:
    Korostynski M., Piechota M., Szklarczyk K., Golda S., Ficek J., Jantas D., Przewlocki R.
    Conference:
    International Society of Psychoneuroendocrinology Conference 2015 (rok: 2015, ), Wydawca: Elsevier
    Data:
    konferencja 8-11.09.2015
    Status:
    Published
    DOI:
    link to the publication
  3. Endophenotypes and transcriptional markers of different stress reactivity in two inbred mouse strains
    Authors:
    Szklarczyk K., Korostynski M., Golda S., Przewlocki R.
    Conference:
    12th World Congress of Biological Psychiatry (rok: 2015, ), Wydawca: World Congress of Biological Psychiatry
    Data:
    konferencja 14-18.06.2015
    Status:
    Published
    DOI:
    link to the publication
  4. Opioid receptors as potential drug targets for controlling fear responses and preventing post-traumatic stress disorder
    Authors:
    Szklarczyk K., Korostynski M., Cieslak P., Wawrzczak-Bargiela A., Przewlocki P.
    Conference:
    European Neuropsychopharmacology Congress (rok: 2014, ), Wydawca: Elsevier
    Data:
    konferencja 18-21 październik 2014
    Status:
    Published
    DOI:
    link to the publication
  5. Susceptibility and resilience to stress–endophenotypes and molecular markers in two inbred mouse strains
    Authors:
    Szklarczyk K., Korostynski M., Golda S., Przewlocki R.
    Conference:
    International Society of Psychoneuroendocrinology Conference 2015 (rok: 2015, ), Wydawca: Elsevier
    Data:
    konferencja 8-11.09.2015
    Status:
    Published
    DOI:
    link to the publication

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