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The effect of imipramine and risperidone on regulation of the chronic mild stress-induced anhedonia and memory impairment by the limbic D1, D2 and D3 receptors in rats.

2013/09/B/NZ7/04098

Keywords:

Chronic stress antidepressants antipsychotics anhedonia cognitive deficits dopamine receptors hormons and protein levels genes expression.

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mariusz Papp 

Number of co-investigators in the project: 6

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 833 300 PLN

Project start date (Y-m-d): 2014-09-08

Project end date (Y-m-d): 2017-04-07

Project duration:: 31 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Effects on BDNF signalling of chronic mild stress, chronic risperidone, and acute intracranial dopamine receptor challenges
    Authors:
    Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Ewa Litwa, Monika Niemczyk, Katarzyna Tota-Glowczyk, Agata Faron-Gorecka, Maciej Kusmider, Joanna Solich, Marta Szlachta and Paul Willner
    Academic press:
    Behavioural Pharmacology (rok: 2018, tom: 29, strony: 537–542), Wydawca: Wolters Kluwer
    Status:
    Published
    DOI:
    10.1097/FBP.0000000000000392 - link to the publication
  2. DOPAMINERGIC MECHANISMS IN MEMORY CONSOLIDATION AND ANTIDEPRESSANT REVERSAL OF A CHRONIC MILD STRESS-INDUCED COGNITIVE IMPAIRMENT
    Authors:
    Mariusz Papp, Piotr Gruca, Magdalena Lason-Tyburkiewicz, Ewa Litwa, Monika Niemczyk, Katarzyna Tota-Glowczyk and Paul Willner
    Academic press:
    Psychopharmacology (rok: 2017, tom: 234, strony: 2571–2585), Wydawca: Springer Science+Business Media.
    Status:
    Published
    DOI:
    10.1007/s00213-017-4651-4 - link to the publication
  1. Risperidone attenuates effects of chronic mild stress on the regulation of recognition memory by D1, D2 and D3 receptors in prefrontal cortex and hippocampus in rats.
    Authors:
    Gruca P, Lason-Tyburkiewicz M, Litwa E, Niemczyk M, PAPP M.
    Conference:
    29the ECNP Congress (rok: 2016, ), Wydawca: Elsevier
    Data:
    konferencja Wrzesień
    Status:
    Published
  2. The effect of chronic mild stress and repeated administration of risperidone on the regulation of recognition memory by D1, D2 and D3 receptors in prefrontal cortex in rats
    Authors:
    Piotr Gruca, Magdalena Lason-Tyburkiewicz, Mariusz Papp
    Conference:
    Dopamine 2016 (rok: 2016, ), Wydawca: Austrian Pharmacological Society (APHAR)
    Data:
    konferencja 5 - 8 września
    Status:
    Published
  3. THE EFFECT OF CHRONIC MILD STRESS ON THE REGULATION OF RECOGNITION MEMORY BY THE LIMBIC D1, D2 AND D3 RECEPTORS IN RATS
    Authors:
    Piotr Gruca, Magdalena Lason-Tyburkiewicz, Katarzyna Tota, Mariusz Papp
    Conference:
    12th International Congress of the Polish Neuroscience Society, Gdańsk, Poland (rok: 2015, ), Wydawca: Polskie Towarzystwo Badań Układu Nerwowego, Instytut Biologii Doświadczalnej im. M. Nenckiego PAN
    Data:
    konferencja 06 – 08 września
    Status:
    Published

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