Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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"Legal Higsh"- CNS effects and neurotoxicity

2013/09/B/NZ7/04104

Keywords:

legal highs brain neurotransmitters neurotoxicity

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Krystyna Gołembiowska 

Number of co-investigators in the project: 5

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 686 690 PLN

Project start date (Y-m-d): 2014-02-17

Project end date (Y-m-d): 2017-02-16

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Kometkowy system do elektroforezy (25 000 PLN)
  2. RATURN - interaktywny system dla swobodnie poruszających się zwierząt (25 000 PLN)
  3. Wirówka stołowa z chłodzeniem oraz rotor (24 000 PLN)
  4. Pompa perystaltyczna (5 000 PLN)
  5. sterownik pomp strzykawkowych.
  6. Łaźnia ultradźwiękowa (1 500 PLN)
  7. Kamera video (2 068 PLN)
  8. Pompy strzykawkowe do mikroinfuzji.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (4)
  1. The effect of repeated-intermittent exposure to 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) during adolescence on learning and memory in adult rats.
    Authors:
    Noworyta-Sokołowska K, Górska AM, Gołembiowska K.
    Academic press:
    Pharmacological Reports (rok: 2018, tom: 70, strony: 890-895), Wydawca: Elseviere
    Status:
    Published
    DOI:
    10.1016/j.pharep.2018.04.001. - link to the publication
  2. Effect of Some Psychoactive Drugs Used as 'Legal Highs' on Brain Neurotransmitters
    Authors:
    Krystyna Gołembiowska, Alexandra Jurczak, Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Anna Górska
    Academic press:
    Neurotoxicity Research (rok: 2016, tom: 29, strony: 394-407), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-015-9569-1 - link to the publication
  3. Neurotoxic Effects of 5-MeO-DIPT: A Psychoactive Tryptamine Derivative in Rats
    Authors:
    Karolina Noworyta-Sokołowska, Katarzyna Kamińska, Grzegorz Kreiner, Zofia Rogóż, Krystyna Gołembiowska
    Academic press:
    Neurotoxicity Research (rok: 2016, tom: 30, strony: 606-619), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-016-9654-0 - link to the publication
  4. Effects of exposure to 5-MeO-DIPT during adolescence on brain neurotransmission and neurotoxicity in adult rats.
    Authors:
    Noworyta-Sokołowska K, Kamińska K, Rzemieniec J, Wnuk A, Wojcieszak J, Górska AM, Kreiner G, Kajta M, Gołembiowska K.
    Academic press:
    Forensic Toxicology (rok: 2019, tom: 37, strony: 45-58), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11419-018-0433-x. - link to the publication
  1. Examionation of illicit drug 5-methoxy-N,N-diisopropyltryptamine, 5-MeO-DIPT actions in the rat brain.
    Authors:
    Noworyta-Sokołowska K., Gołembiowska K.
    Conference:
    22nd Scientific Conference of the Society on Neuroimmune Pharmacology, Kraków, Poland (rok: 2016, ), Wydawca: Springer
    Data:
    konferencja 6-9 April
    Status:
    Published
  2. Neurochemical Aspects of 5-Methoxy-Diisopropyltryptamine (5-MeO-DIPT, 'Foxy') in rat brain regions
    Authors:
    Karolina Noworyta-Sokołowska, Krystyna Gołembiowska
    Conference:
    Mediterranean Neuroscience Society (rok: 2015, ), Wydawca: Neuroscience Society
    Data:
    konferencja 12-15 June
    Status:
    Published
  3. The actions of 5-methoxy-diisopropyltryptamine ('foxy') in rat prefrontal cortex and striatum
    Authors:
    Karolina Noworyta-Sokołowska
    Conference:
    The 12th International Symposium Molecular Basis of Pathology and Therapy in Neurological Disorders (rok: 2014, ), Wydawca: Folia Neuropathologica 52/3 Termedia
    Data:
    konferencja 20-21 November
    Status:
    Published
  4. The effect of designer drugs on neurotransmission in the rat brain
    Authors:
    Katarzyna Kamińska, Alexandra Jurczak, Krystyna Gołembiowska
    Conference:
    The Days of Neurochemistry "Neuropsychoimmunological mechanisms in the pathology of neurodegenerative diseases. From biomarkers to therapeutics" (rok: 2015, ), Wydawca: Folia Neuropathologica
    Data:
    konferencja 22-23 October
    Status:
    Published

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