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Information on the principal investigator and host institution

Information of the project and the call

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Define the role and modulation of immune diabetes changed factors - their importance to the action of analgesics.

2012/05/N/NZ4/02416

Keywords:

diabetic neuropathy cytokines intercellular interactions

Descriptors:

  • NZ4_4: Pathophysiology
  • NZ4_7: Neurophysiology
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Magdalena Żychowska 

Number of co-investigators in the project: 3

Call: PRELUDIUM 3 - announced on 2012-03-15

Amount awarded: 149 955 PLN

Project start date (Y-m-d): 2013-02-25

Project end date (Y-m-d): 2016-12-24

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (10)
  1. Microglial Inhibition Influences XCL1/XCR1 Expression and Causes Analgesic Effects in a Mouse Model of Diabetic Neuropathy.
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Anna Piotrowska, Grzegorz Kreiner, Joanna Mika
    Academic press:
    Anesthesiology (rok: 2016, tom: 125, strony: 573-89), Wydawca: Wolters Kluwer
    Status:
    Published
    DOI:
    10.1097/ALN.0000000000001219 - link to the publication
  2. Minocyklina jako modulator czynników neuroimmunologicznych w bólu neuropatycznym
    Authors:
    Ewelina Rojewska, Magdalena Żychowska, Katarzyna Popiołek-Barczyk, Barbara Przewłocka, Joanna Mika
    Academic press:
    Ból (rok: 2013, tom: 14, strony: 29-36), Wydawca: ELIPSA-JAIM
    Status:
    Published
  3. Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Grzegorz Kreiner, Irena Nalepa, Barbara Przewlocka, Joanna Mika
    Academic press:
    Journal of Neuroimmunology (rok: 2013, tom: 262, strony: 35-45), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jneuroim.2013.06.005 - link to the publication
  4. The Role of Some Chemokines from the CXC Subfamily in a Mouse Model of Diabetic Neuropathy
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Dominika Pilat, Joanna Mika
    Academic press:
    Journal of Diabetes Research (rok: 2015, tom: 2015, strony: 45304), Wydawca: Hindawi
    Status:
    Published
    DOI:
    10.1155/2015/750182 - link to the publication
  5. Mechanisms and pharmacology of diabetic neuropathy – experimental and clinical studies
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Barbara Przewlocka, Joanna Mika
    Academic press:
    Pharmacological Reports (rok: 2013, tom: 65, strony: 1601-1610), Wydawca: Elsevier
    Status:
    Published
  1. Diabetes and pain
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Grzegorz Kreiner, Irena Nalepa, Barbara Przewlocka, Joanna Mika
    Conference:
    22th International sympozjum "Molecular and physiological aspects of regulatory processes of the organism" (rok: 2013, ), Wydawca: Wydawnictwo Abaton
    Data:
    konferencja 14-15.06.2013
    Status:
    Published
  2. Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy.
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Grzegorz Kreiner, Irena Nalepa, Barbara Przewlocka, Joanna Mika
    Conference:
    NEURONUS (rok: 2014, ), Wydawca: nie dotyczy
    Data:
    konferencja 25-27.04
    Status:
    Published
  3. The neuroimmunological basis of the neuropathic pain
    Authors:
    Joanna Mika, Ewelina Rojewska, Wioletta Makuch, Magdalena Zychowska, Katarzyna Popiołek-Barczyk, Barbara Przewlocka
    Conference:
    22th International sympozjum "Molecular and physiological aspects of regulatory processes of the organism" (rok: 2013, ), Wydawca: Wydawnictwo Abaton
    Data:
    konferencja 14-15.06.2013
    Status:
    Published
  4. The role of CXCL9 and CXCL12 in nociceptive transmission under diabetes
    Authors:
    Dominika Pilat, Magdalena Zychowska, Ewelina Rojewska, Joanna Mika
    Conference:
    The 12th International Symposium Molecular basis of pathology and therapy in neurological disorders" (rok: 2014, ), Wydawca: TERMEDIA Publishing House
    Data:
    konferencja 20-21.11
    Status:
    Published
  5. The involvement of TNF-family in diabetic neuropathy in mice.
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Grzegorz Kreiner, Irena Nalepa, Barbara Przewlocka, Joanna Mika
    Conference:
    NEURONUS (rok: 2013, ), Wydawca: nie dotyczy
    Data:
    konferencja 9-11.05.2013
    Status:
    Published
  6. The role of CC chemokine ligand 3 (CCL3) in a mouse diabetic neuropathy - in vivo and in vitro studies
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Anna Piotrowska, Dominika Pilat, Joanna Mika
    Conference:
    XII European Meeting on Glial Cells in Health and Disease (rok: 2015, ), Wydawca: Wiley
    Data:
    konferencja 15-18.07
    Status:
    Published
  7. Wpływ minocykliny na rozwój neuropatii cukrzycowej poprzez modulację czynników immunologicznych
    Authors:
    Magdalena Żychowska, Ewelina Rojewska, Dominika Piłat, Barbara Przewłocka, Joanna Mika
    Conference:
    VI Sympozjum "Postępy w leczeniu bólu" (rok: 2015, ), Wydawca: INDEX COPERNICUS
    Data:
    konferencja 15-17.10
    Status:
    Published
  8. WPŁYW MINOCYKLINY NA KOMÓRKI GLEJOWE ORAZ PROFIL UWALNIANYCH INTERLEUKIN W PRZEBIEGU NEUROPATII CUKRZYCOWEJ U MYSZY
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Joanna Mika, Barbara Przewlocka
    Conference:
    XXX Zimowa Szkoła Instytutu Farmakologii PAN (rok: 2013, ), Wydawca: Wydawnictwo Platan
    Data:
    konferencja 19-22.02
    Status:
    Published
  9. The role of CXCL1 and CXCL5 in in nociceptive transmission in a mouse model of diabetic neuropathy
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Dominika Pilat, Joanna Mika
    Conference:
    The 12th International Symposium Molecular basis of pathology and therapy in neurological disorders" (rok: 2014, ), Wydawca: TERMEDIA Publishing House
    Data:
    konferencja 20-21.11
    Status:
    Published
  10. The role of selected chemokines from the CXC group in a mouse diabetic neuropathy model
    Authors:
    Magdalena Zychowska, Ewelina Rojewska, Dominika Pilat, Joanna Mika
    Conference:
    NEURONUS (rok: 2015, ), Wydawca: nie dotyczy
    Data:
    konferencja 17-19.04
    Status:
    Published