Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The influence of the serotonergic system on the regulation of liver CYP activity in hepatocellular carcinoma

2012/07/D/NZ4/00814

Keywords:

liver CYP isoforms serotonin hepatocellular carcinoma

Descriptors:

  • NZ4_8: Neuroendocrinology
  • NZ4_11: Metabolism
  • NZ4_5: Anatomical pathology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Marta Kot 

Number of co-investigators in the project: 3

Call: SONATA 4 - announced on 2012-09-15

Amount awarded: 499 000 PLN

Project start date (Y-m-d): 2013-07-16

Project end date (Y-m-d): 2017-06-15

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Real-Time PCR System z przenośną bazą dokującą wyniki (164 744 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Erratum to "Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms" [Food Chem. Toxicol. 116 Part B (2018) 369-378].
    Authors:
    Kot Marta, Daujat-Chavanieu Martine
    Academic press:
    Food and Chemical Toxicology (FCT) (rok: 2018, tom: 118, strony: 471-472), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fct.2018.05.028. - link to the publication
  2. Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms.
    Authors:
    Kot Marta, Daujat-Chavanieu Martine
    Academic press:
    Food and Chemical Toxicology (FCT) (rok: 2018, tom: 116(Pt B):, strony: 369-378), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fct.2018.04.051 - link to the publication
  3. The impact of serotonergic system dysfunction on the regulation of P4501A isoforms during liver insufficiency and consequences for thyroid hormone homeostasis
    Authors:
    Kot Marta, Daujat-Chavanieu Martine
    Academic press:
    Food and Chemical Toxicology (FCT) (rok: 2016, tom: 97, strony: 70-81), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fct.2016.08.027 - link to the publication
  1. HORMONAL CONTEXT IN THE REGULATION OF CYTOCHROME P450 (CYP) DURING LIVER INSUFFICIENCY WITH SEROTONERGIC SYSTEM DYSFUNCTION
    Authors:
    Marta Kot
    Conference:
    The 11th International ISSX (International Society for the Study of Xenobiotics) Meeting (rok: 2107, ), Wydawca: Elsevier
    Data:
    konferencja 12-16 June, 2016
    Status:
    Published
    DOI:
    link to the publication
  2. The role of the serotonergic system in the regulation of cytochrome P450 during hepatocarcinogenesis
    Authors:
    Marta Kot
    Conference:
    The 51st Congress of the European Societies of Toxicology (EUROTOX) (rok: 2015, ), Wydawca: Copyright © 2015 Published by Elsevier Ireland Ltd.
    Data:
    konferencja 13 - 16 September 2015
    Status:
    Published

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