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Information on the principal investigator and host institution

Information of the project and the call

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Impact of selective modulators of estrogen and aryl hydrocarbon receptors on hypoxia/ischemia-induced neuronal cell damage

2011/01/N/NZ3/04786

Keywords:

SERMs SAhRMs apoptosis neuroprotection hypoxia ischemia

Descriptors:

  • NZ4_8: Neuroendocrinology
  • NZ4_17:
  • NZ3_3: Apoptosis

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

INSTYTUT FARMAKOLOGII PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Rzemieniec 

Number of co-investigators in the project: 3

Call: PRELUDIUM 1 - announced on 2011-03-15

Amount awarded: 254 020 PLN

Project start date (Y-m-d): 2011-12-08

Project end date (Y-m-d): 2014-12-07

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (4)
  1. Neuroprotective potential of selective modulators of estrogen and aryl hydrocarbon receptors: the effects of raloxifene, daidzein, and 3,3'-diindolylmethane in response to hypoxia
    Authors:
    Rzemieniec Joanna, Litwa Ewa, Lasoń Władysław, Kajta Małgorzata
    Academic press:
    Pharmacological Reports (rok: 2012, tom: 64, strony: 468-469), Wydawca: Elsevier BV
    Status:
    Published
    DOI:
    10.1016/S1734-1140(12)70797-1 - link to the publication
  2. Selective Aryl Hydrocarbon Receptor Modulator 3,3'-Diindolylmethane Impairs AhR and ARNT Signaling and Protects Mouse Neuronal Cells Against Hypoxia.
    Authors:
    Joanna Rzemieniec; Ewa Litwa; Agnieszka Wnuk; Wladyslaw Lason; Wojciech Krzeptowski; Malgorzata Kajta
    Academic press:
    Molecular Neurobiology (rok: 2015, tom: -, strony: -), Wydawca: SpringerLink
    Status:
    Published
    DOI:
    10.1007/s12035-015-9471-0 - link to the publication
  3. Impact of raloxifene and 3,3'-diindolylmethane on neuronal cells exposed to hypoxia
    Authors:
    Joanna Rzemieniec, Ewa Litwa, Władysław Lason, Małgorzata Kajta
    Academic press:
    Acta Neurobiologiae Experimentalis (rok: 2013, tom: 73, strony: 184), Wydawca: The Nencki Institute
    Status:
    Published
    DOI:
    brak - link to the publication
  4. Anti-ischemic effects of 3,3'-diindolylmethane in mouse hippocampal cells at early developmental stages
    Authors:
    Joanna Rzemieniec, Ewa Litwa, Agnieszka Wnuk, Władysław Lasoń, Małgorzata Kajta
    Academic press:
    Folia NEUROPATHOLOGICA (rok: 2014, tom: 52, strony: 357), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/fn.2014.45656 - link to the publication
  5. Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERß or GPR30 signalling
    Authors:
    Joanna Rzemieniec; Ewa Litwa; Agnieszka Wnuk; Wladyslaw Lason; Aniela Golas; Wojciech Krzeptowski; Malgorzata Kajta
    Academic press:
    The Journal of Steroid Biochemistry and Molecular Biology (rok: 2015, tom: 146, strony: 26-37), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.jsbmb.2014.05.005. - link to the publication
  1. RALOXIFENE PROTECTS NEURONS AGAINST HYPOXIA IN ER BETA- AND G-PROTEIN-COUPLED RECEPTOR 30 - INDEPENDENT PATHWAYS
    Authors:
    Joanna Rzemieniec, Agnieszka Wnuk, Ewa Litwa, Aniela Gołas, Władysław Lasoń, Małgorzata Kajta
    Conference:
    7th International Meeting Steroids and Nervous System (rok: 2013, ), Wydawca: NICO NEUROSCIENCE INSTITUTE CAVALIERI OTTOLENGHI
    Data:
    konferencja 16-20 02
    Status:
    Published
  2. Neuroprotective capacity of raloxifene and daidzein against glutamate-induced apoptosis in mouse hippocampal cells
    Authors:
    Joanna Rzemieniec, Ewa Litwa, Agnieszka Wnuk , Władysław Lasoń, Małgorzata Kajta
    Conference:
    Glutamate/GABA and neuro-glia-vascular interplay in norm and pathology (rok: 2014, ), Wydawca: Instytut Farmakologii PAN, Kraków
    Data:
    konferencja 21 - 24 05
    Status:
    Published
  3. 3,3'-DIINDOLYLMETHANE PROTECTS NEURONS AGAINST HYPOXIA IN AHR-AND ARNT-, BUT NOT ERBETA-DEPENDENT PATHWAYS
    Authors:
    Joanna Rzemieniec, E. Litwa, A. Wnuk, W. Lason, M. Kajta
    Conference:
    9th FENS Forum of Neuroscience (rok: 2014, ), Wydawca: Forum of Neuroscience
    Data:
    konferencja 05-09 07
    Status:
    Published
    DOI:
    link to the publication
  4. Neuroprotective effects of phytoestrogens and selective modulators of nuclear receptors
    Authors:
    Rzemieniec J , Litwa E , Wnuk A, Lasoń W, Kajta M.
    Conference:
    XIX International Congress of the Polish Pharmacological Society Świnoujście (rok: 2015, ), Wydawca: Pharmacological Reports, Elsevier
    Data:
    konferencja 17-19 września
    Status:
    Published
    DOI:
    link to the publication

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