Identification of cytochrome P450 isoenzymes involved in the metabolism of levomepromazine in the human
2011/01/B/NZ4/04859
Keywords
Descriptors
- NZ4_16: Farmacja
- NZ4_17: Farmakologia
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Instytut Farmakologii PAN
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
OPUS 1 – announced on 2011-03-15
- Amount awarded
- 175 860 PLN
- Project start date
- 2011-12-15
- Project end date
- 2013-12-14
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Equipment purchased [PL]
- Termostat i układ optyczny do zestawu HPLC MERCK-HITACHI. Cost: 30 000 PLN
Information in the final report
Publication in academic press/journals (2)
-
The influence of amitriptyline and carbamazepine on levomepromazine metabolism in human liver: An in vitro study
- Authors:
- Wójcikowski J., Basińska A., Boksa J., Daniel W.A.
- Academic press:
- Pharmacological Reports (year: 2014, volume: 66, pages: 1122-1126), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.pharep.2014.07.012 – link to the publication
-
The cytochrome P450-catalyzed metabolism of levomepromazine: a phenothiazine neuroleptic with a wide spectrum of clinical application
- Authors:
- Wójcikowski J., Basińska A., Daniel W.A.
- Academic press:
- Biochemical Pharmacology (year: 2014, volume: 90, pages: 188-195), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.bcp.2014.05.005 – link to the publication
Articles in post-conference publications (3)
-
Concentration-dependent contribution of human cytochrome P450 isoenzymes to the metabolism of levomepromazine
- Authors:
- Wójcikowski J., Basińska A., Daniel W. A.
- Conference:
- 26th European College of Neuropsychopharmacology (year: 2013, pages: S457), Publisher: Elsevier
- Date:
- conference 5-9 października
- Status:
- Published
-
The metabolism of levomepromazine by human cytochrome P450 isoenzymes.
- Authors:
- Wójcikowski J., Daniel W.A.
- Conference:
- 28th CINP World Congress of Neuropsychopharmacology (year: 2012, pages: 105), Publisher: Cambrige Journals
- Date:
- conference 3-7 czerwca
- Status:
- Published
- DOI:
- link to the publication
-
Characterization of human cytochrome P450 isoenzymes involved in the metabolism of levomepromazine
- Authors:
- Wójcikowski J., Basińska A., Daniel W. A.
- Conference:
- 11th World Congress of Biological Psychiatry (year: 2013, pages: P-18-021), Publisher: 11th World Congress of Biological Psychiatry
- Date:
- conference 23-27 czerwca
- Status:
- Published