Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Molecular markers of stress resilience in animal model of depression

2012/07/B/NZ7/01164

Keywords:

stress resilience chronic mild stress model miRNA arrays RT-PCR serum brain tissue primary neuronal culture

Descriptors:

  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marta Dziedzicka-Wasylewska 

Number of co-investigators in the project: 9

Call: OPUS 4 - announced on 2012-09-15

Amount awarded: 1 027 190 PLN

Project start date (Y-m-d): 2013-07-18

Project end date (Y-m-d): 2016-07-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Fluorymetr Qubit.
  2. Automatyczna stacja pipetująca (70 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Reciprocal MicroRNA Expression in Mesocortical Circuit and Its Interplay with Serotonin Transporter Define Resilient Rats in the Chronic Mild Stress
    Authors:
    Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Solich J, Kolasa M, Papp M, Dziedzicka-Wayslewska M
    Academic press:
    Molecular Neurobiology (rok: 2017, tom: 54, strony: 5741-5751), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-016-0107-9 - link to the publication
  2. Time-dependent miR-16 serum fluctuations together with reciprocal changes in the expression level of miR-16 in mesocortical circuit contribute to stress resilient phenotype in chronic mild stress - An animal model of depression.
    Authors:
    Zurawek D, Kusmider M, Faron-Gorecka A, Gruca P, Pabian P, Kolasa M, Solich J, Szafran-Pilch K, Papp M, Dziedzicka-Wasylewska M.
    Academic press:
    European Neuropsychopharmacology (rok: 2016, tom: 26, strony: 23-36), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.euroneuro.2015.11.013 - link to the publication
  1. Changes in miRNA expression profile between stress-vulnerable and stress-resilient rats in Chronic Mild Stress (CMS) - an animal model of depression
    Authors:
    Zurawek D, Faron-Gorecka A, Kusmider M, Kolasa M, Pabian P, Solich J, Szafran K, Gruca P, Papp M and Dziedzicka-Wasylewska M
    Conference:
    12th International Conference on Cognitive Neuroscience (rok: 2014, ), Wydawca: Frontiers Media S.A.
    Data:
    konferencja 27.07 - 31.07
    Status:
    Published