Projects funded by the NCN

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201 projects found matching your search criteria :

  1. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

    Call: HARMONIA 7 , Panel: NZ2

    Principal investigator: Stefan Mateusz Mordalski

    Instytut Farmakologii PAN

  2. Adaptacyjne podejmowanie decyzji u zwierząt z komórkowo specyficzną inaktywacją receptorów glutaminianu w układzie dopam...

    Call: ETIUDA 4 , Panel: NZ4

    Principal investigator: Przemysław Eligiusz Cieślak

    Instytut Farmakologii PAN

  3. Determination of the mechanisms and potential targets for neuropathic pain therapy by investigating pharmacological inte...

    Call: PRELUDIUM 12 , Panel: NZ7

    Principal investigator: Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  4. The role of codependent 5-HT1a and 5-HT7 receptor signalling in the hippocampal stress response

    Call: PRELUDIUM 12 , Panel: NZ4

    Principal investigator: Marcin Siwiec

    Instytut Farmakologii PAN

  5. The role of brain glutamatergic system in the neuroendocrine regulation of cytochrome P450 expression and activity in th...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  6. Regulation of alternative Dclk1 kinase gene isoforms by psychotropic drugs

    Call: PRELUDIUM 12 , Panel: NZ3

    Principal investigator: Magdalena Agata Zygmunt

    Instytut Farmakologii PAN

  7. The effects of thyroid hormones in the brain in an animal model of depression

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  8. How microglia-astrocyte interaction affects neuronal functioning in the dopaminergic system. Analysis of the protective ...

    Call: OPUS 14 , Panel: NZ7

    Principal investigator: dr Katarzyna Zofia Kuter

    Instytut Farmakologii PAN

  9. Molecular markers of stress resilience in animal model of depression

    Call: OPUS 4 , Panel: NZ7

    Principal investigator: prof. Marta Dziedzicka-Wasylewska

    Instytut Farmakologii PAN

  10. The influence of glucagon-like peptied-1 receptor agaonists on regulation of coticotropin-releasing hormone gene promote...

    Call: PRELUDIUM 4 , Panel: NZ7

    Principal investigator: Jan Stanisław Detka

    Instytut Farmakologii PAN

  11. Involvement of 5-HT1A receptor signal pathway in the antidepressant effect of zinc

    Call: HARMONIA 4 , Panel: NZ7

    Principal investigator: dr Bernadeta Szewczyk

    Instytut Farmakologii PAN

  12. Molecular mechanism for the effects of stress hormones on development of drug addiction

    Call: MAESTRO 4 , Panel: NZ3

    Principal investigator: prof. Ryszard Przewłocki

    Instytut Farmakologii PAN

  13. Development of a tool for automatic evaluation of complexes of ligands with serotonin receptors based on the application...

    Call: PRELUDIUM 5 , Panel: NZ2

    Principal investigator: Sabina Marta Podlewska

    Instytut Farmakologii PAN

  14. Neuronal and nonneuronal mechanisms of Bont/A effects in neuropathic pain development - behavioral and biochemical studi...

    Call: HARMONIA 5 , Panel: NZ4

    Principal investigator: dr hab. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  15. The significance of the serotonergic innervation of the brain hypothalamus in the regulation of cytochrome P450

    Call: OPUS 6 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  16. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Bogusława Budziszewska

    Instytut Farmakologii PAN

  17. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

    Call: PRELUDIUM 7 , Panel: NZ4

    Principal investigator: Agnieszka Wnuk

    Instytut Farmakologii PAN

  18. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

    Call: SONATA 8 , Panel: NZ7

    Principal investigator: dr Rafał Kurczab

    Instytut Farmakologii PAN

  19. The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY...

    Call: PRELUDIUM 8 , Panel: NZ7

    Principal investigator: Agnieszka Basińska-Ziobroń

    Instytut Farmakologii PAN

  20. Chronic pain in obesity: from cellular mechanisms to new strategies for targeted therapy.

    Call: SONATA 17 , Panel: NZ5

    Principal investigator: dr Anna Piotrowska-Murzyn

    Instytut Farmakologii PAN

  21. Biological roles of transcriptional networks activated in the brain by psychotropic drugs

    Call: PRELUDIUM BIS 3 , Panel: NZ7

    Principal investigator: dr hab. Michał Korostyński

    Instytut Farmakologii PAN

  22. Plasticity of neuroanatomically identified synaptic inputs and functions of the dorsal raphe nucleus in an animal model ...

    Call: OPUS 25 , Panel: NZ4

    Principal investigator: prof. Krzysztof Tokarski

    Instytut Farmakologii PAN

  23. Potential pharmacological strategies aimed at alleviating cognitive dysfunctions accompanying oncological therapy while ...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Monika Wierońska

    Instytut Farmakologii PAN

  24. Impact of endocrine disrupting chemicals - 4,para nonylphenol - on toxic effects mediated by xenobiotic receptors PXR an...

    Call: PRELUDIUM 1 , Panel: NZ4

    Principal investigator: Ewa Joanna Litwa

    Instytut Farmakologii PAN

  25. Define the role and modulation of immune diabetes changed factors - their importance to the action of analgesics.

    Call: PRELUDIUM 3 , Panel: NZ4

    Principal investigator: Magdalena Małgorzata Żychowska

    Instytut Farmakologii PAN

  26. Probing the selectivity of zinc allosteric modulation in various serotonin receptor subtypes

    Call: PRELUDIUM 3 , Panel: NZ7

    Principal investigator: Grzegorz Marek Satała

    Instytut Farmakologii PAN

  27. Opioid-induced analgesia and hyperalgesia in neuropathic pain - mechanisms and druggable targets

    Call: OPUS 15 , Panel: NZ7

    Principal investigator: prof. Barbara Elżbieta Przewłocka

    Instytut Farmakologii PAN

  28. Wpływ wybranych chemokin na właściwości komórek nerwowych i przekaźnictwo synaptyczne w obszarze kompleksu ciała migdało...

    Call: ETIUDA 7 , Panel: NZ4

    Principal investigator: Joanna Ewa Sowa

    Instytut Farmakologii PAN

  29. Endocannabinoid regulation of the motivational tone at the mesolimbic system driven by inflammation

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: prof. Katarzyna Maria Starowicz-Bubak

    Instytut Farmakologii PAN

  30. Kappa opioid receptors integrate neuronal signaling involved in social behavior

    Call: OPUS 18 , Panel: NZ7

    Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

    Instytut Farmakologii PAN

  31. Zinc deficient diet as a trigger for treatment-resistant depression in chronically stressed mice. Understanding the mech...

    Call: OPUS 19 , Panel: NZ5

    Principal investigator: dr hab. Bernadeta Szewczyk

    Instytut Farmakologii PAN

  32. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress...

    Call: PRELUDIUM 9 , Panel: NZ7

    Principal investigator: dr Ewa Izabela Trojan

    Instytut Farmakologii PAN

  33. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto...

    Call: OPUS 9 , Panel: NZ4

    Principal investigator: dr Magdalena Joanna Zaniewska

    Instytut Farmakologii PAN

  34. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

    Call: PRELUDIUM 9 , Panel: NZ4

    Principal investigator: Dariusz Marek Żurawek

    Instytut Farmakologii PAN

  35. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi...

    Call: PRELUDIUM 9 , Panel: ST6

    Principal investigator: Krzysztof Rataj

    Instytut Farmakologii PAN

  36. Transcription factor MeCP2 as an intracellular object of study on the mechanism of depression and as a potential pharmac...

    Call: SONATA 5 , Panel: NZ7

    Principal investigator: dr Magdalena Jolanta Sowa-Kućma

    Instytut Farmakologii PAN

  37. "Legal Higsh"- CNS effects and neurotoxicity

    Call: OPUS 5 , Panel: NZ7

    Principal investigator: prof. Krystyna Czesława Gołembiowska

    Instytut Farmakologii PAN

  38. Noradrenergic modulation of cocaine-seeking

    Call: SONATA 6 , Panel: NZ4

    Principal investigator: dr Wojciech Barnaba Solecki

    Instytut Farmakologii PAN

  39. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha...

    Call: PRELUDIUM 7 , Panel: NZ6

    Principal investigator: Katarzyna Curzytek

    Instytut Farmakologii PAN

  40. Unusual 5-HT6 receptor ligands

    Call: OPUS 7 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  41. Evaluation of interactions of aripiprazole, the atypical amtipsychotic drug, with the selected antidepressants in the ra...

    Call: OPUS 12 , Panel: NZ7

    Principal investigator: dr hab. Zofia Maria Rogóż

    Instytut Farmakologii PAN

  42. Comparative effects of 1-methyl-1,2,3,4-tetrahydroisoquinoline (1MeTIQ) and olanzapine on the cognitive dysfunction meas...

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: dr hab. Agnieszka Wąsik

    Instytut Farmakologii PAN

  43. Development of unique molecular probes: low-basicity agonists for the study of 5-HT7 receptor function

    Call: OPUS 13 , Panel: NZ7

    Principal investigator: prof. Andrzej Jacek Bojarski

    Instytut Farmakologii PAN

  44. Maternal obesity as a risk factor of autism spectrum disorder in offspring - in search of the role of the gut microbiota...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr Dawid Mateusz Gawliński

    Instytut Farmakologii PAN

  45. New strategies in the pharmacotherapy of neuropathic pain based on modulation of the chemokine system and its influence ...

    Call: OPUS 22 , Panel: NZ7

    Principal investigator: prof. Joanna Gabriela Mika

    Instytut Farmakologii PAN

  46. The role of the immune checkpoints in the pathomechanism of depressive disorders.

    Call: OPUS 22 , Panel: NZ6

    Principal investigator: prof. Marta Wanda Kubera

    Instytut Farmakologii PAN

  47. The evaluation of therapeutic potential of β-caryophyllene in animal schizophrenia model - behavioral and molecular stud...

    Call: PRELUDIUM 21 , Panel: NZ7

    Principal investigator: dr Magdalena Białoń

    Instytut Farmakologii PAN

  48. Brain cytochrome P450 as a new target for the treatment of neurological and psychiatric diseases. Studies with human neu...

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Władysława Anna Daniel

    Instytut Farmakologii PAN

  49. The cross-talk between 5-HTR2A and mGluR2 as a window for antidepressant effects of psilocybin.

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Andrzej Mikołaj Pilc

    Instytut Farmakologii PAN

  50. The effect of prolonged treatment with the new antipsychotics brexpiprazole and lumateperone on human liver function usi...

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Przemysław Jan Danek

    Instytut Farmakologii PAN

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