Projects funded by the NCN

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422 projects found matching your search criteria :

  1. Evaluation of pharmacological activity of new, nonselective gamma-aminobutyric acid (GABA) transport inhibitors in some ...

    Call: OPUS 3 , Panel: NZ7

    Principal investigator: dr hab. Kinga Sałat

    Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

  2. Organometallic inhibitors of tubulin polymerisation. Synthesis, anticancer activities and tubulin affinities.

    Call: OPUS 3 , Panel: ST5

    Principal investigator: dr hab. Damian Plażuk

    Uniwersytet Łódzki, Wydział Chemii

  3. Modifications of aglycones of leucomycins via Michael addition and Huisgen dipolar cycloaddition as a new routes of synt...

    Call: SONATA BIS 1 , Panel: ST5

    Principal investigator: dr hab. Piotr Przybylski

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  4. Identification of amino acid residues located in positions P7 and P8 of model inhibitor of proprotein convertases that d...

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: Izabela Małuch

    Uniwersytet Gdański, Wydział Chemii

  5. Synthesis of mononucleotide N2,N2,7-trimethylguanosine cap analogues as translation inhibitors in Ascaris suum

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Karolina Ewa Piecyk

    Uniwersytet Warszawski, Wydział Chemii

  6. The influence of metabolic pathway inhibitors on the development and quality of bovine embryos produced in vitro.

    Call: OPUS 3 , Panel: NZ9

    Principal investigator: dr hab. Dorota Marta Cieślak

    Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

  7. Pattern-Specific Inhibitors (PSI) - introduction and basic characteristics of a new class of inhibitors that block recog...

    Call: OPUS 3 , Panel: NZ6

    Principal investigator: dr Krzysztof Guzik

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  8. Conjugates of cap analogs with nanomaterials and biomolecules with potential applications in pharmacology or diagnostics

    Call: SONATA 1 , Panel: ST5

    Principal investigator: dr Joanna Kowalska

    Uniwersytet Warszawski, Wydział Fizyki

  9. Role of ruthenium complexes interaction with NO in the context of angiogenesis inhibition.

    Call: PRELUDIUM 3 , Panel: ST5

    Principal investigator: dr Maria Józefa Oszajca

    Uniwersytet Jagielloński, Wydział Chemii

  10. Peptide splicing - the mechanism and its application for designing compounds with potential use in medicinal practice

    Call: OPUS 1 , Panel: ST5

    Principal investigator: prof. Krzysztof Rolka

    Uniwersytet Gdański, Wydział Chemii

  11. Research into the understanding of a defense mechanism of wheat (Triticum aestivum) in response to feeding Oulema spp. -...

    Call: OPUS 2 , Panel: NZ9

    Principal investigator: dr hab. Aleksandra Julia Obrępalska-Stęplowska

    Instytut Ochrony Roślin - Państwowy Instytut Badawczy

  12. Solution NMR investigations of human cystatin C - structure, dynamics and protein-ligand interactions.

    Call: PRELUDIUM 2 , Panel: ST4

    Principal investigator: Martyna Ewa Maszota-Zieleniak

    Uniwersytet Gdański, Wydział Chemii

  13. Identifying of novel virus-encoded GW proteins that inhibit plant and animal RNAi-based defense systems.

    Call: PRELUDIUM 2 , Panel: NZ2

    Principal investigator: Andrzej Zieleziński

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  14. Hydrogen exchange mass spectrometry (HXMS) for studying human serum amyloid A fibril formation.

    Call: PRELUDIUM 2 , Panel: NZ5

    Principal investigator: Marta Sosnowska

    Uniwersytet Gdański, Wydział Chemii

  15. New approaches towards modulating selective and functional activities of antisense oligonucleotides

    Call: OPUS 2 , Panel: ST5

    Principal investigator: prof. Ryszard Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  16. Novel urease inhibitors as means to control ureolytic microbial pathogens

    Call: OPUS 2 , Panel: NZ6

    Principal investigator: dr Agnieszka Grabowiecka

    Politechnika Wrocławska

  17. Novel insights into inhibition of PD-L1/PD-1 immune checkpoint – discovery and optimization of covalent PD-L1 inhibitors...

    Call: SONATA 20 , Panel: ST5

    Principal investigator: dr Radosław Dariusz Kitel

    Uniwersytet Jagielloński

  18. A new feature of the yeast Kazachstania humilis species: Growth-inhibitory properties against a broad spectrum of bacter...

    Call: OPUS 28 , Panel: NZ9

    Principal investigator: dr hab. Anna Sikora

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  19. Environmental modulation of CDK4/6 inhibitor efficacy: Impact of mycotoxin alternariol exposure on anti-cancer therapies

    Call: SONATA 20 , Panel: NZ5

    Principal investigator: dr Anna Dominika Walczak-Szeffer

    Uniwersytet Medyczny w Łodzi

  20. Phytochemicals as inhibitors of polylactide's photooxidation and thermooxidation

    Call: SONATA 20 , Panel: ST11

    Principal investigator: dr Aleksander Mateusz Hejna

    Politechnika Poznańska

  21. Novel hybrid coatings with advanced antimicrobial properties for surface modification in atmospheric water harvesting sy...

    Call: OPUS 27 , Panel: ST11

    Principal investigator: prof. Anna Elżbieta Kowalewska

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  22. Analysis of pharmacokinetic, pharmacodynamic and molecular determinants of intolerance and resistance to the Janus kinas...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Marta Katarzyna Karaźniewicz-Łada

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  23. Frog skin derived cyclic peptide as a molecular scaffold to create a novel tool for combining visualization and inhibiti...

    Call: PRELUDIUM 23 , Panel: ST5

    Principal investigator: Aleksandra Dorota Helbik-Maciejewska

    Uniwersytet Gdański

  24. Development of novel screening method for identifying xanthine oxidase inhibitors – towards new drug candidates for gout...

    Call: PRELUDIUM 23 , Panel: ST4

    Principal investigator: Monika Katarzyna Rola

    Politechnika Łódzka

  25. Small molecule modulators of the tumor necrosis factor alpha signaling pathway for the inhibition of inflammatory proces...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: prof. Tadeusz Holak

    Uniwersytet Gdański

  26. Innovative Small Molecule Inhibitors Targeting LAG-3 and MHCII Complex for Tumour Immunotherapy

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr Jacek Plewka

    Uniwersytet Jagielloński

  27. Behavioral timescale plasticity in inhibitory synapses: mechanisms and implications

    Call: OPUS 27 , Panel: NZ4

    Principal investigator: dr Grzegorz Tadeusz Wiera

    Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu

  28. Controlling the covalent activity of a PD-L1 inhibitors with light

    Call: PRELUDIUM 23 , Panel: NZ7

    Principal investigator: Wiktor Jan Uzar

    Uniwersytet Jagielloński

  29. Development and characterization of novel multitargeted organometallic tubulin polymerization inhibitors for enhancing t...

    Call: OPUS 27 , Panel: NZ7

    Principal investigator: dr hab. Damian Nestor Plażuk

    Uniwersytet Łódzki

  30. Early Intervention with mTOR Inhibitors for Neuropsychiatric Symptoms in Tuberous Sclerosis Complex: Unveiling Developme...

    Call: DAINA 3 , Panel: NZ4

    Principal investigator: prof. Ewelina Anna Knapska

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  31. Interaction between temporal predictability and action control in ADHD and Parkinson's Disease: behavioural, neurophysio...

    Call: SONATINA 8 , Panel: HS6

    Principal investigator: dr Inga Justyna Korolczuk

    Uniwersytet Medyczny w Lublinie

  32. Selective inhibition of Janus kinases for the treatment of autoimmune hepatitis: Translational PK/PD modelling from mole...

    Call: SONATA 19 , Panel: NZ7

    Principal investigator: dr Artur Świerczek

    Uniwersytet Jagielloński, Collegium Medicum

  33. Inhibitory Functional Networks in Addiction Development within Social Context - a Missing Piece of Puzzle

    Call: OPUS 26 , Panel: NZ4

    Principal investigator: dr Marzena Stefaniuk

    Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

  34. Design, synthesis and biological evaluation of Steroid Sulfatase Inhibitors based on organophosphorus compounds.

    Call: SONATA 2 , Panel: NZ7

    Principal investigator: dr Sebastian Demkowicz

    Politechnika Gdańska

  35. Flozins as potential inhibitors of aortic stenosis progression in patients with concomitant type 2 diabetes: impact on v...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr hab. Joanna Natorska

    Uniwersytet Jagielloński

  36. Restoring Beta-cell Integrity through Targeted SPOP Inhibition and PDX-1 Preservation

    Call: OPUS 26 (LAP) , Panel: NZ7

    Principal investigator: dr Anna Czarna

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  37. Modulation of the N-glycosylation as a tool to improve the CAR-T immunotherapy efficacy

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Agnieszka Graczyk-Jarzynka

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  38. Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr Magdalena Wujak

    Uniwersytet Mikołaja Kopernika w Toruniu, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

  39. Novel aspects of the mechanisms of vascular toxicity of tyrosine kinase inhibitors: studies on their proinflammatory act...

    Call: OPUS 26 , Panel: NZ5

    Principal investigator: dr Tomasz Krzysztof Prajsnar

    Uniwersytet Jagielloński, Wydział Biologii

  40. Can extracts from Epilobium sp. inhibit proliferation of prostate cell LNCaP by influencing the activity of histone acet...

    Call: SONATA 1 , Panel: NZ4

    Principal investigator: dr hab. Anna Karolina Kiss

    Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

  41. Functional and structural analysis of anticancer drugs as protein biosynthesis inhibitors

    Call: OPUS 26 , Panel: NZ7

    Principal investigator: dr hab. Witold Szaflarski

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

  42. Design and synthesis of new rifampicin analogs as a source of effective bacterial RNA polymerase inhibitors

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr hab. Piotr Przybylski

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

  43. Design and Development of Serine Hydroxymethyltransferase-2 (SHMT2) Inhibitors Blocking Tumor Growth

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr hab. Miłosz Ruszkowski

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  44. The inhibition of NMDAR and TRPM4 coupling - a hope for novel therapeutic target for the treatment of the ischemic brain...

    Call: SONATA BIS 13 , Panel: NZ7

    Principal investigator: dr Bartosz Sebastian Pomierny

    Uniwersytet Jagielloński, Collegium Medicum

  45. Physiological significance and clinical implications of global and local inhibition of NRF2 transcriptional activity in ...

    Call: SONATA BIS 13 , Panel: NZ4

    Principal investigator: dr hab. Aleksandra Barbara Piechota-Polańczyk

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  46. Molecular mechanisms of DNA damage triggered by PIM kinases inhibition and its consequences for activation of innate imm...

    Call: OPUS 25 , Panel: NZ5

    Principal investigator: prof. Przemysław Juszczyński

    Instytut Hematologii i Transfuzjologii

  47. Theoretical prediction, chemical synthesis and biological analysis of a novel class of HSPA5 inhibitors

    Call: OPUS 25 , Panel: ST4

    Principal investigator: prof. Arkadiusz Chworoś

    Centrum Badań Molekularnych i Makromolekularnych Polskiej Akademii Nauk

  48. Compounds modulating function of telomeric proteins TRF1 and TRF2

    Call: OPUS 25 , Panel: NZ7

    Principal investigator: prof. Maciej Wojciech Bagiński

    Politechnika Gdańska, Wydział Chemiczny

  49. Synthesis and biological activity evaluation of new hybrid derivatives of tacrine and melatonin as potential cholinester...

    Call: OPUS 2 , Panel: ST5

    Principal investigator: dr Anna Zawadzka

    Uniwersytet Warszawski, Wydział Chemii

  50. Development of dual immuno-oligo- biosensors for monitoring and controlling of the metastatic colorectal cancer and inve...

    Call: OPUS 25 , Panel: ST4

    Principal investigator: dr hab. Magdalena Stobiecka

    Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

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