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Publication in academic press/journals (7)

1. DYRK1A inhibitors leucettines and TGF-β inhibitor additively stimulate insulin production in beta cells, organoids, and isolated mouse islets

   Authors:

   Pucelik B, Barzowska A, Czarna A

   Academic press:

   PLOS ONE (year: 2023, volume: 18(5), pages: e0285208), Publisher: PLOS ONE

   Status:

   Published

   DOI:

   10.1371/journal.pone.0285208 – link to the publication

2. Diabetic Kinome Inhibitors—A New Opportunity for β-Cells Restoration.

   Authors:

   Pucelik B, Barzowska A, Dąbrowski JM, Czarna A.

   Academic press:

   International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 6,97430555555556), Publisher: MDPI

   Status:

   Published

   DOI:

   10.3390/ijms22169083 – link to the publication

3. Microscale thermophoresis (MST) and spectral shift (SpS) in drug discovery

   Authors:

   Jakub S. Nowak, Anna Czarna, Przemysław Grudnik, Przemyslaw Grygier, Katarzyna Pustelny, Andreas Langer, Grzegorz Dubin

   Academic press:

   TrAC Trends in Analytical Chemistry (year: 2024, volume: 176, pages: 117716), Publisher: Elsevier

   Status:

   Published

   DOI:

   10.1016/j.trac.2024.117716 – link to the publication

4. Exploring Novel GSK-3β Inhibitors for Anti-Neuroinflammatory and Neuroprotective Effects: Synthesis, Crystallography, Computational Analysis, and Biological Evaluation

   Authors:

   Izabella Góral, Tomasz Wichur, Emilia Sługocka, Przemysław Grygier, Monika Głuch-Lutwin, Barbara Mordyl, Ewelina Honkisz-Orzechowska, Natalia Szałaj, Justyna Godyń, Dawid Panek, Paula Zaręba, Anna Sarka, Paweł Żmudzki, Gniewomir Latacz, Katarzyna Pustelny, Adam Bucki, Anna Czarna, Filipe Menezes, and Anna Więckowska

   Academic press:

   ACS Chemical Neuroscience (year: 2024, volume: 15 (17), pages: 3181-3201), Publisher: American Chemical Society

   Status:

   Published

   DOI:

   10.1021/acschemneuro.4c00365 – link to the publication

5. DYRK1A Kinase Inhibitors Promote β-Cell Survival and Insulin Homeostasis

   Authors:

   Barzowska A, Pucelik B, Pustelny K, Matsuda A, Martyniak A, Stępniewski J, Maksymiuk A, Dawidowski M, Rothweiler U, Dulak J, Dubin G, Czarna A.

   Academic press:

   Cells (year: 2021, volume: 10, pages: 1,94652777777778), Publisher: MDPI

   Status:

   Published

   DOI:

   10.3390/cells10092263 – link to the publication

6. Binding mechanism and biological effects of flavone DYRK1A inhibitors for the design of new antidiabetics

   Authors:

   Katarzyna Pustelny, Przemyslaw Grygier, Agata Barzowska, Barbara Pucelik, Alex Matsuda, Krzysztof Mrowiec, Emilia Slugocka, Grzegorz M Popowicz, Grzegorz Dubin, Anna Czarna

   Academic press:

   Scientific reports (year: 2023, volume: 13, pages: 18114), Publisher: Nature Publishing Group UK

   Status:

   Published

   DOI:

   10.1038/s41598-023-44810-3 – link to the publication

7. Silmitasertib (CX-4945), a Clinically Used CK2-Kinase Inhibitor with Additional Effects on GSK3β and DYRK1A Kinases: A Structural Perspective

   Authors:

   Przemyslaw Grygier, Katarzyna Pustelny, Jakub Nowak, Przemyslaw Golik, Grzegorz M. Popowicz, Oliver Plettenburg, Grzegorz Dubin, Filipe Menezes, and Anna Czarna

   Academic press:

   Journal of Medicinal Chemistry (year: 2023, volume: 66 (6), pages: 4009-4024), Publisher: ACS Publications

   Status:

   Published

   DOI:

   10.1021/acs.jmedchem.2c01887 – link to the publication