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Information of the project and the call

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Search for structure-antimicrobial activity correlation for selected boraheterocycles

2018/31/B/ST5/00210

Keywords:

antimicrobial activity enzyme inhibitors heterocycles

Descriptors:

  • ST5_23:
  • ST5_16:
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Warszawska, Wydział Chemiczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Sergiusz Luliński 

Number of co-investigators in the project: 11

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 726 200 PLN

Project start date (Y-m-d): 2019-07-24

Project end date (Y-m-d): 2024-07-23

Project duration:: 36 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (2)
  1. Differential Sensing of Saccharides Based on an Array of Fluorinated Benzosiloxaborole Receptors
    Authors:
    Paweł Ćwik, Patrycja Ciosek-Skibińska, Marcin Zabadaj, Sergiusz Luliński, Krzysztof Durka, Wojciech Wróblewski
    Academic press:
    Sensors (rok: 2020, tom: 20, strony: 3540), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/s20123540 - link to the publication
  2. Mutant Prevention Concentration, Frequency of Spontaneous Mutant Selection, and Mutant Selection Window—a New Approach to the In Vitro Determination of the Antimicrobial Potency of Compounds
    Authors:
    Joanna Krajewska, Stefan Tyski, Agnieszka E. Laudy
    Academic press:
    Antimicrobial Agents and Chemotherapy (rok: 2023, tom: 67, strony: 45305), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/aac.01373-22 - link to the publication
  3. Expedient Synthesis of Oxaboracyclic Compounds Based on Naphthalene and Biphenyl Backbone and Phase- Dependent Luminescence of their Chelate Complexes
    Authors:
    Krzysztof Durka, Paulina H. Marek-Urban, Krzysztof Nowicki, Jakub Drapała, Katarzyna N. Jarzembska, Piotr Łaski, Aleksandra Grzelak, Marek Dąbrowski, Krzysztof Woźniak, Sergiusz Luliński
    Academic press:
    Chemistry—A European Journal (rok: 2022, tom: 28, strony: e202104492), Wydawca: Wiley-VCH
    Status:
    Accepted for publication
    DOI:
    10.1002/chem.202104492 - link to the publication
  4. Exploring the effect of substitution patterns on the symmetry of hydrogen-bonded supramolecular motifs in functionalized benzosiloxaboroles
    Authors:
    Krzysztof Durka, Adam Zuba, Paulina H. Marek-Urban, Krzysztof Nowicki, Jakub Drapała, Krzysztof Woźniak, Sergiusz Luliński
    Academic press:
    CrystEngComm (rok: 2023, tom: 25, strony: 6329-6342), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/d3ce00880k - link to the publication
  5. Heteroelement Analogues of Benzoxaborole and Related Ring Expanded Systems
    Authors:
    Krzysztof Nowicki, Piotr Pacholak, Sergiusz Luliński
    Academic press:
    Molecules (rok: 2021, tom: 26, strony: 5464), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26185464 - link to the publication
  6. Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity
    Authors:
    Joanna Krajewska, Krzysztof Nowicki, Krzysztof Durka, Paulina H. Marek-Urban, Patrycja Wińska, Tomasz Stępniewski, Krzysztof Woźniak, Agnieszka E. Laudy, Sergiusz Luliński
    Academic press:
    RSC Advances (rok: 2022, tom: 12, strony: 23099–23117), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/d2ra03910a - link to the publication
  7. Aromatic Diboronic Acids as Effective KPC/AmpC Inhibitors
    Authors:
    Joanna Krajewska, Piotr Chyży, Krzysztof Durka, Patrycja Wińska, Krystiana A. Krzyśko, Sergiusz Luliński, Agnieszka E. Laudy
    Academic press:
    Molecules (rok: 2023, tom: 28, strony: 7362), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules28217362 - link to the publication
  8. Development of structurally extended benzosiloxaboroles – synthesis and in vitro biological evaluation
    Authors:
    P.iotr Pacholak, Joanna Krajewska, Patrycja Wińska, Jolanta Dunikowska, Urszula Gogowska, Jolanta Mierzejewska, Krzysztof Durka, Krzysztof Woźniak, Agmieszka E. Laudy, Sergiusz Luliński
    Academic press:
    RSC Advances (rok: 2021, tom: 11, strony: 25104–25121), Wydawca: RSC
    Status:
    Published
    DOI:
    10.1039/d1ra04127d - link to the publication
  1. WIELOETAPOWA METODA OTRZYMYWANIA INOKULUM BAKTERII O GĘSTOŚCI ≥10^11 CFU/ML
    Authors:
    Joanna Krajewska, Agnieszka E. Laudy
    Conference:
    XXIX ogólnopolski Zjazd Polskiego Towarzystwa Mikrobiologów (rok: 2022, ), Wydawca: Polskie Towarzystwo Mikrobiologów
    Data:
    konferencja 15-17.09.2022
    Status:
    Published
  2. Nowe parametry wyznaczania zakresu stężeń, w którym może dochodzić do selekcji lekoopornych mutantów, tzw. mutant selection window (MSW) – istotny etap badań przedklinicznych
    Authors:
    Joanna Krajewska, Sergiusz Luliński, Agnieszka Laudy
    Conference:
    XXIX ogólnopolski Zjazd Polskiego Towarzystwa Mikrobiologów (rok: 2022, ), Wydawca: Polskie Towarzystwo Mikrobiologów
    Data:
    konferencja 15-17.09.2022
    Status:
    Published

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