Połączone działanie agonistów receptorów adenozynowych i antagonistów receptora P2Y12 zwiększa hamowanie funkcji płytek krwi (Adenosine receptor agonists and P2Y12 receptor antagonists exhibit combined inhibitory effect on blood platelet function)

2019/32/T/NZ3/00333

Descriptors

  • NZ3_001: Biologia komórki
  • NZ3_002: Fizjologia komórki
  • NZ7_014: Farmacja, farmakoterapia, farmakologia

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Nina Małgorzata Wolska

Number of co-investigators in the project: 2

Call

ETIUDA 7 – announced on 2018-12-14

Amount awarded
158 656 PLN
Project start date
2019-10-01
Project end date
2020-09-30
Project duration
12 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Adenosine Receptor Agonists Increase the Inhibition of Platelet Function by P2Y 12 Antagonists in a cAMP- and Calcium-Dependent Manner

    Authors:
    Nina Wolska, Hassan Kassassir, Boguslawa Luzak, Cezary Watala, Marcin Rozalski
    Academic press:
    Pharmaceuticals (year: 2020, volume: 13(8), pages: 177), Publisher: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ph13080177 – link to the publication
  2. NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis

    Authors:
    Dina Vara, Reiner K. Mailer, Anuradha Tarafdar, Nina Wolska, Marco Heestermans, Sandra Konrath, Manuela Spaeth, Thomas Renné, Katrin Schröder, and Giordano Pula
    Academic press:
    Arteriosclerosis, Thrombosis, and Vascular Biology (year: 2021, volume: 41(2), pages: 683–697), Publisher: Lippincott Williams & Wilkins on behalf of the American Heart Association
    Status:
    Published
    DOI:
    10.1161/ATVBAHA.120.315565 – link to the publication
  3. Diabetes and Thrombosis: A Central Role for Vascular Oxidative Stress

    Authors:
    Aishwarya R Vaidya, Nina Wolska, Dina Vara, Reiner K Mailer, Katrin Schröder, Giordano Pula
    Academic press:
    Antioxidants (year: 2021, volume: 10(5), pages: 706), Publisher: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/antiox10050706 – link to the publication

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