Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Effect of therapy with selective serotonin reuptake inhibitors and physical exercise on blood brain barrier permeability, selected neurotransmitters in prefrontal cortex and hippocampus, kinurenine pathway and mood in major depressive disorder.

2019/33/N/NZ5/02815

Keywords:

major depressive disorder physical exercise blood brain barrier neurotransmitters kinurenine pathway

Descriptors:

  • NZ5_007:
  • NZ4_010:
  • NZ4_004:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Instytutem Medycyny Morskiej i Tropikalnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Marta Anna Małkiewicz 

Number of co-investigators in the project: 3

Call: PRELUDIUM 17 - announced on 2019-03-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2020-02-28

Project end date (Y-m-d): 2026-02-27

Project duration:: 72 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Substances of abuse and the blood brain barrier: Interactions with physical exercise
    Authors:
    Marta A Małkiewicz, Andrzej Małecki, Michal Toborek, Arkadiusz Szarmach, Paweł J Winklewski
    Academic press:
    Neuroscience & Biobehavioral Reviews (rok: 2020, tom: 119, strony: 204-216), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neubiorev.2020.09.026 - link to the publication
  2. Heart Rate Variability and Interoception in Periodic Limb Movements in Sleep: Interference with Psychiatric Disorders?
    Authors:
    Marta A. Małkiewicz, Krzysztof S. Malinowski, Małgorzata Grzywińska, Eemil Partinen, Markku Partinen, Jan Pyrzowski, Magdalena Wszędybył-Winklewska
    Academic press:
    Journal of Clinical Medicine (rok: 2024, tom: 13, strony: brak), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm13206129 - link to the publication
  3. Effect of series of periodic limb movements in sleep on blood pressure, heart rate and high frequency heart rate variability
    Authors:
    Malkiewicz MA, Grzywinska M, Malinowski KS, Partinen E, Partinen M, Cubala WJ, Winklewski PJ, Sieminski M.
    Academic press:
    Polish Journal of Neurology and Neurosurgery, PJNNS; Neurologia i Neurochirurgia Polska (rok: 2023, tom: Ahead of print, strony: Ahead of print), Wydawca: VM Media Group
    Status:
    Published
    DOI:
    10.5603/pjnns.95117 - link to the publication
  4. Effect of series of periodic limb movements in sleep on blood pressure, heart rate and high frequency heart rate variability
    Authors:
    Malkiewicz MA, Grzywinska M, Malinowski KS, Partinen E, Partinen M, Cubala WJ, Winklewski PJ, Sieminski M.
    Academic press:
    Polish Journal of Neurology and Neurosurgery, PJNNS; Neurologia i Neurochirurgia Polska (rok: 2023, tom: Ahead of print, strony: Ahead of print), Wydawca: VM Media Group
    Status:
    Published
    DOI:
    10.5603/pjnns.95117 - link to the publication

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