Association of TXNDC5 and calreticulin with decreased ER stress, allowing resistant multiple myeloma cells to by-pass proteasome inhibition.
2018/29/N/NZ5/00651
Keywords
Descriptors
- NZ5_3: Patogeneza chorób człowieka
Panel
NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution
Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski
Voivodeship: wielkopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 15 – announced on 2018-03-15
- Amount awarded
- 210 000 PLN
- Project start date
- 2019-02-18
- Project end date
- 2022-02-17
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (2)
-
Bortezomib- and carfilzomib-resistant myeloma cells show increased activity of all three arms of the unfolded protein response
- Authors:
- Tadeusz Kubicki, Kinga Bednarek, Magdalena Kostrzewska-Poczekaj, Magdalena Luczak, Krzysztof Lewandowski, Lidia Gil, Malgorzata Jarmuz-Szymczak, Dominik Dytfeld
- Academic press:
- American Journal of Cancer Research (year: 2022, volume: 12(7), pages: 3280-3293), Publisher: E-CENTURY PUBLISHING CORP
- Status:
- Published
-
Endoplasmic reticulum stress and proteasome inhibitors in multiple myeloma – a room for improvement.
- Authors:
- Tadeusz Kubicki, Lidia Gil, Dominik Dytfeld
- Academic press:
- Polish Archives of Internal Medicine (year: 2021, volume: 131(4), pages: 361-368), Publisher: Medycyna Praktyczna
- Status:
- Published
- DOI:
- 10.20452/pamw.15896 – link to the publication