Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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A new approach of vision restoration based on modified Rabies virus tracing technique

2019/34/E/NZ5/00434

Keywords:

Rabies virus neuronal tracing inhibitory interneurons bipolar cells retina vision restoration gene therapy viral therapy

Descriptors:

  • NZ5_007:
  • NZ5_008:

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Andrzej Tomasz Foik 

Number of co-investigators in the project: 4

Call: SONATA BIS 9 - announced on 2019-06-17

Amount awarded: 3 457 800 PLN

Project start date (Y-m-d): 2020-05-26

Project end date (Y-m-d): 2026-05-25

Project duration:: 72 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  1. Visual system hyperexcitability and compromised V1 receptive field properties in early-stage Retinitis Pigmentosa in mice
    Authors:
    Leinonen H, Lyon DC, Palczewski K, Foik AT
    Academic press:
    eNeuro (tom: Vol 9 Issue 3, strony: ), Wydawca: Society for Neuroscience
    Status:
    Published
    DOI:
    10.1523/ENEURO.0107-22.2022 - link to the publication
  2. Traumatic brain injury to primary visual cortex produces long-lasting circuit dysfunction
    Authors:
    Frankowski, J.C., Foik, A.T., Tierno, A. et al
    Academic press:
    Communications Biology , Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s42003-021-02808-5 - link to the publication
  3. Traumatic brain injury to primary visual cortex produces long-lasting circuit dysfunction
    Authors:
    Frankowski, J.C., Foik, A.T., Tierno, A. et al
    Academic press:
    Current Biology , Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s42003-021-02808-5 - link to the publication
  4. Distinct mouse models of Stargardt disease display differences in pharmacological targeting of ceramides and inflammatory responses
    Authors:
    Engfer, Z. J., Lewandowski, D., Dong, Z., Palczewska, G., Zhang, J., Kordecka, K., Płaczkiewicz, J., Panas, D., Foik, A. T., Tabaka, M., & Palczewski, K.
    Academic press:
    Proceedings of the National Academy of Sciences (tom: 120 (50), strony: e2314698120), Wydawca: PNAS
    Status:
    Published
    DOI:
    10.1073/PNAS.2314698120 - link to the publication
  5. In vivo base editing rescues cone photoreceptors in a mouse model of early-onset inherited retinal degeneration
    Authors:
    Elliot H. Choi, Susie Suh, Andrzej T. Foik, Henri Leinonen, Gregory A. Newby, Xin D. Gao, Samagya Banskota, Thanh Hoang , Samuel W. Du, Zhiqian Dong, Aditya Raguram, Sajeev Kohli, Seth Blackshaw, David C. Lyon, David R. Liu, Krzysztof Palczewski
    Academic press:
    Nature Communications (), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41467-022-29490-3 - link to the publication

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