Projects funded by the NCN


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235 projects found matching your search criteria :

  1. De novo design of cavity-incorporating mini-proteins and their application in catalysis

    Call: OPUS 22 , Panel: ST4

    Principal investigator: prof. Łukasz Berlicki

    Politechnika Wrocławska

  2. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula...

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  3. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

  4. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  5. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Instytut Hematologii i Transfuzjologii

  6. Coming out of the shadow of iron – manganese as an important player at the host-pathogen interface.

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Małgorzata Ostrowska

    Uniwersytet Wrocławski, Wydział Chemii

  7. CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

    Call: SONATA 17 , Panel: NZ2

    Principal investigator: dr Adam Kawałek

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  8. Dependence of growth of young pig from protein qualitative digestion - peptide vs. amino acid absorption

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Kamil Zaworski

    Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego Polskiej Akademii Nauk

  9. New Thrombospondin-1-deriving Peptides as TGF-β Activators of Cosmeceutical Interest

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Patrycja Ledwoń

    Politechnika Wrocławska

  10. Small, well-armed fighters vs. powerful, devastating enemies - modified peptidecomplexes from human saliva in the fight ...

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Joanna Wątły

    Uniwersytet Wrocławski, Wydział Chemii

  11. In the search of new insecticides: immunomodulatory role of tachykinin-related peptides and their potential usage in pes...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr Arkadiusz Urbański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  12. Design of metal-peptide complexes based on amyloid β sequence with a His-2 binding motif as selective receptors in elect...

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Aleksandra Tobolska

    Politechnika Warszawska

  13. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Kierzek

    Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

  14. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  15. Characterization of bioactive peptides from chicken feather keratin and products of their transformations occurring duri...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Antoni Taraszkiewicz

    Politechnika Gdańska

  16. Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Adam Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  17. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  18. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Poręba

    Politechnika Wrocławska

  19. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Ewa Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

  20. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  21. The role of MOTS-c peptide in the regulation of adrenal cortex physiological function

    Call: SONATA BIS 10 , Panel: NZ4

    Principal investigator: prof. Marcin Ruciński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  22. In solution or in the membrane? Determination of partition of beta-amyloid peptides between the water and phospholipid p...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

  23. Direct monitoring of the local dynamic rearrangement of the Alzheimer's peptides secondary structure upon the aggregatio...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: dr hab. Ewelina Lipiec

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  24. Making use of siderophore transport systems to deliver peptide nucleic acids to bacterial cells

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Joanna Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  25. Studies over the dissociation of peptides in non-aqueous enviroments and the development of a universal counter-ion exch...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  26. Bioactive compounds in the immune response of Galleria mellonella infected with the entomopathogenic bacterium Pseudomon...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Iwona Wojda

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  27. A peptidomimetic strategy to improve the antimicrobial properties of calcitermin

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Denise Bellotti

    Uniwersytet Wrocławski, Wydział Chemii

  28. Structural studies of the influence of selected surfactants on the amyloidogenic properties of various forms of beta pep...

    Call: ETIUDA 8 , Panel: ST4

    Principal investigator: Michalina Wilkowska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  29. Novel role of peroxisome proliferator-activated receptor α in the regulationof amyloid β peptide metabolism and mitochon...

    Call: PRELUDIUM 18 , Panel: NZ4

    Principal investigator: Sylwia Wójtowicz

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego Polskiej Akademii Nauk

  30. Application of N-(2-thioethyl)glycine analogues in orthogonal cleavage of peptides from solid support

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Magdalena Wierzbicka

    Uniwersytet Wrocławski, Wydział Chemii

  31. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Lesner

    Uniwersytet Gdański, Wydział Chemii

  32. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  33. Evaluation of in vivo and in vitro effects of cyanobacterial peptides on aquatic organisms

    Call: OPUS 18 , Panel: NZ9

    Principal investigator: dr hab. Adam Bownik

    Uniwersytet Przyrodniczy w Lublinie, Wydział Biologii Środowiskowej

  34. Therapeutic application of temporin derivatives in infectious diseases caused by intracellular pathogens.

    Call: SONATA 15 , Panel: NZ6

    Principal investigator: dr Anna Golda

    Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

  35. Isolated chromophoric assemblies organized and controlled from a peptide scaffold

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Marco Farinone

    Uniwersytet Wrocławski, Wydział Chemii

  36. Model for antimicrobial peptide-dependent evolution of plastids

    Call: PRELUDIUM 18 , Panel: NZ8

    Principal investigator: Filip Pietluch

    Uniwersytet Wrocławski, Wydział Biotechnologii

  37. MOLECULAR INSIGHTS INTO BIOSYNTHESIS OF PEPTIDE AZOLE ANTIBIOTICS

    Call: SONATA 15 , Panel: NZ1

    Principal investigator: dr Dmitry Gilyarov

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  38. Synthetic self-assembled models of transmembrane proteins

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Grzegorz Wołczański

    Uniwersytet Wrocławski, Wydział Chemii

  39. Conjugates of aminoglycosides with amphipathic peptides as antibacterials

    Call: SONATA 15 , Panel: NZ1

    Principal investigator: dr Monika Wojciechowska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  40. Lipophilic Prodrug Charge Masking (LPCM) as a novel strategy to enhance oral bioavailability of charged active peptides....

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Agata Gitlin-Domagalska

    Uniwersytet Gdański, Wydział Chemii

  41. The role of kappa opioid receptors during chronic intestinal inflammation and colitis-associated colorectal cancer – foc...

    Call: SONATA 15 , Panel: NZ7

    Principal investigator: dr Marta Zielińska

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  42. Functionalized peptide hydrogels as a tool to support skeletal muscle regeneration and therapeutic potential of myogenic...

    Call: OPUS 18 , Panel: NZ5

    Principal investigator: prof. Maria Ciemerych-Litwinienko

    Uniwersytet Warszawski, Wydział Biologii

  43. Novel mechanisms of PAD activity regulation. Substrate specificity and activation of peptidyl arginine deiminase in the ...

    Call: GRIEG 1 , Panel: NZ1

    Principal investigator: dr Tomasz Kantyka

    Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

  44. Development of a new protein-protein docking method based on the flexible docking of short peptide fragments.

    Call: OPUS 17 , Panel: NZ2

    Principal investigator: dr Mateusz Kurciński

    Uniwersytet Warszawski

  45. Effects of proteasome inhibition on mitochondrial homeostasis.

    Call: OPUS 17 , Panel: NZ5

    Principal investigator: prof. Agnieszka Chacińska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  46. New regioselective chemical and biochemical strategies for proteins labeling

    Call: OPUS 17 , Panel: ST4

    Principal investigator: prof. Artur Krężel

    Uniwersytet Wrocławski, Wydział Biotechnologii

  47. Evaluation of characteristic interactions of synthetic peptides derived from HarmOBP7 aldehyde binding site.

    Call: PRELUDIUM 17 , Panel: ST5

    Principal investigator: Tomasz Wasilewski

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  48. Conjugates of metallacarboranes and short cationic peptides with antibacterial and anticancer activity.

    Call: SONATINA 3 , Panel: NZ7

    Principal investigator: dr Krzysztof Fink

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

  49. Innovative hybrid materials useful in the syntheis of dressings for the treatment of diabetic foot ulcers

    Call: OPUS 16 , Panel: ST8

    Principal investigator: dr hab. Beata Kolesińska

    Politechnika Łódzka, Wydział Chemiczny

  50. Fundamentals of copper exchange kinetics between model peptides and small molecules.

    Call: PRELUDIUM 16 , Panel: ST5

    Principal investigator: Radosław Kotuniak

    Instytut Biochemii i Biofizyki Polskiej Akademii Nauk