Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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SLPI-dependent cutaneous antimicrobial and antiviral immunity.

2017/25/B/NZ6/01003

Keywords:

secretory leukocyte protease inhibitor antimicrobial peptides skin

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ6_3: Animal immunology
  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Cichy 

Number of co-investigators in the project: 4

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 843 440 PLN

Project start date (Y-m-d): 2018-01-26

Project end date (Y-m-d): 2021-10-25

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. zakup mikroskopu konfokalnego (500 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Chemerin-derived peptide Val66-Pro85 is effective in limiting methicillin-resistant S. aureus skin infection.
    Authors:
    Aneta Zegar, Urszula Godlewska, Dorota Kozłowska-Chmielewska, Pawel Majewski, Brian A Zabel, Joanna Cichy
    Academic press:
    Frontiers in Microbiology (rok: 2021, tom: 12, strony: 45299), Wydawca: Frontiers Media SA
    Status:
    Published
    DOI:
    10.3389/fmicb.2021.742610 - link to the publication
  2. Differential expansion of circulating human MDSC subsets in patients with cancer, infection and inflammation
    Authors:
    Cassetta L, Bruderek K, Skrzeczynska-Moncznik J, Osiecka O, Hu X, Rundgren IM, Lin A, Santegoets K, Horzum U, Godinho-Santos A, Zelinskyy G, Garcia-Tellez T, Bjelica S, Taciak B, Kittang AO, Höing B, Lang S, Dixon M, Müller V, Utikal JS, Karakoç D, Yilmaz KB, Górka E, Bodnar L, Anastasiou OE, Bourgeois C, Badura R, Kapinska-Mrowiecka M, Gotic M, Ter Laan M, Kers-Rebel E, Król M, Santibañez JF, Müller-Trutwin M, Dittmer U, de Sousa AE, Esendağlı G, Adema G, Loré K, Ersvær E, Umansky V, Pollard JW, Cichy J, Brandau S.
    Academic press:
    The Journal for ImmunoTherapy of Cancer (rok: 2020, tom: 8, strony: e001223), Wydawca: BMJ Journals
    Status:
    Published
    DOI:
    10.1136/jitc-2020-001223 - link to the publication
  3. Differences in Staining for Neutrophil Elastase and its Controlling Inhibitor SLPI Reveal Heterogeneity among Neutrophils in Psoriasis
    Authors:
    Skrzeczynska-Moncznik J, Zabieglo K, Osiecka O, Morytko A, Brzoza P, Drozdz L, Kapinska-Mrowiecka M, Korkmaz B, Pastuszczak M, Kosalka-Wegiel J, Musial J, Cichy J.
    Academic press:
    J Invest Dermatol. (rok: 2020, ), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jid.2019.12.015 - link to the publication
  4. Architecture of antimicrobial skin defense.
    Authors:
    Kwiecien K, Zegar A, Jung J, Brzoza P, Kwitniewski M, Godlewska U, Grygier B, Kwiecinska P, Morytko A, Cichy J.
    Academic press:
    Cytokine & Growth Factor Reviews (rok: 2019, tom: 49, strony: 70-84), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cytogfr.2019.08.001 - link to the publication
  5. Secretory Leukocyte Protease Inhibitor is present in circulating and tissue-recruited human eosinophils and regulates their migratory function
    Authors:
    Osiecka O, Skrzeczynska-Moncznik J, Morytko A, Mazur A, Majewski P, Bilska B, Kapinska-Mrowiecka M, Kosalka-Wegiel J, Pastuszczak M, Pyza E, Cichy J.
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 12, strony: 45302), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fimmu.2021.737231 - link to the publication
  6. Secretory Leukocyte Protease Inhibitor regulates nerve reflex-mediated skin barrier function in psoriasis.
    Authors:
    Kwiecinska P, Grygier B, Morytko A, Sanecka-Duin AMajchrzak-Gorecka M, Kwitniewski M, Kapinska-Mrowiecka M, Porebski G, Cichy J.
    Academic press:
    Journal of European Academy of Dermatology and Venorology (rok: 2022, tom: 12, strony: nie dotyczy), Wydawca: Wiley and Sons
    Status:
    Published
    DOI:
    10.1111/jdv.18065 - link to the publication

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