Zmiana języka

Projects search

Solid state NMR spectroscopy as a tool supporting mechanochemistry development

2017/25/B/ST4/02684

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne
  • ST4_11: Nowoczesne metody prowadzenia reakcji i procesów
  • ST4_4: Struktura i architektura molekularna

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Centrum Badań Molekularnych i Makromolekularnych PAN

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Marek Józef Potrzebowski

Number of co-investigators in the project: 5

Call

OPUS 13 – announced on 2017-03-15

Amount awarded
1 207 600 PLN
Project start date
2018-01-19
Project end date
2023-01-18
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer stacjonarny z oprogramowaniem (Windows, Microsoft Oficce, Gauss View, Corel). Cost: 5 000 PLN
  2. Modyfikacja sondy CP-MAS 1.3mm H/BB. Cost: 60 000 PLN
  3. Młyn planetarno - kulowy z akcesoriami (naczynia reakacyjne, kule mielące itp.). Cost: 100 000 PLN
  4. Naczynia mielące do młyna.
  5. Zestaw komputerowy.
  6. modernizacja głowicy MASDVT.

Information in the final report

Publication in academic press/journals (8)

  1. Understanding the formation of apremilast cocrystals

    Authors:
    Marta K. Dudek, Ewelina Wielgus, Piotr Paluch, Justyna Śniechowska, Maciej Kostrzewa, Graeme M. Day, Grzegorz D. Bujacz, Marek J. Potrzebowski
    Academic press:
    Acta Crystallographica Section B (year: 2019, volume: B75, pages: 803-814), Publisher: Wiley: IUCr Journals
    Status:
    Published
    DOI:
    10.1107/S205252061900917X – link to the publication

  2. π‑Philic Molecular Recognition in the Solid State as a Driving Forcefor Mechanochemical Formation of Apremilast Solvates andCocrystals

    Authors:
    Marta K. Dudek, Maciej Kostrzewa, Piotr Paluch, Marek J. Potrzebowski
    Academic press:
    Crystal Growth & Design (year: 2018, volume: 18, pages: 3959-3970), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.cgd.8b00301 – link to the publication

  3. tructural variety of heterosynthons in linezolid cocrystals with modified thermal properties

    Authors:
    Mehrnaz Khalaji, Aneta Wróblewska, Ewelina Wielgus, Grzegorz D. Bujacz, Marta K. Dudek, Marek J. Potrzebowski
    Academic press:
    Acta Crystallographica Section B (year: 2020, volume: 76, pages: 892-912), Publisher: Wiley: IUCr Journals
    Status:
    Published
    DOI:
    10.1107/S2052520620010896 – link to the publication

  4. Virtual Cocrystal Screening Methods as Tools to Understand the Formation of Pharmaceutical CocrystalsA Case Study of Linezolid, a Wide-Range Antibacterial Drug

    Authors:
    Mehrnaz Khalaji, Marek J. Potrzebowski, Marta K. Dudek
    Academic press:
    Cryst. Growth Des. (year: 2021, volume: 21, pages: 2301-2314), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acs.cgd.0c01707 – link to the publication

  5. Expedient synthesis of N –Oxy-Heterocyclic Carbenes (NOHC) ligands and metal complexes using mechanochemistry

    Authors:
    Aneta Wróblewska, Gaëtan Lauriol, Grzegorz Mlostoń , Xavier Bantreilc , Frédéric Lamaty
    Academic press:
    Journal of Organometallic Chemistry (year: 2021, volume: 949, pages: 121914-121920), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jorganchem.2021.121914 – link to the publication

  6. Porous Molecular Capsules as Non-Polymeric Transducers of Mechanical Forces to Mechanophores

    Authors:
    Hanna Jędrzejewska, Ewelina Wielgus, Sławomir Kaźmierski, Halina Rogala, Michał Wierzbicki, Aneta Wróblewska, Tomasz Pawlak, Marek J. Potrzebowski, Agnieszka Szumna
    Academic press:
    Chemistry A European Journal (year: 2020, volume: 26, pages: 1558-1566), Publisher: Wiley-VCH
    Status:
    Published
    DOI:
    10.1002/chem.201904024. – link to the publication

  7. Cocrystals Divorce and Marriage: When a Binary System Meets an Active Multifunctional Synthon in a Ball Mill

    Authors:
    Marta K. Dudek, Justyna Śniechowska, Aneta Wróblewska, Sławomir Kaźmierski
    Academic press:
    Chemistry A European Journal (year: 2020, volume: 26, pages: 13264-13273), Publisher: Wiley-VCH GmbH
    Status:
    Published
    DOI:
    10.1002/chem.202002238 – link to the publication

  8. Application of 1-Hydroxy-4,5-Dimethyl-Imidazole 3-Oxide as Coformer in Formation of Pharmaceutical Cocrystals

    Authors:
    Aneta Wróblewska, Justyna Śniechowska, Sławomir Kaźmierski, Ewelina Wielgus, Grzegorz D. Bujacz, Grzegorz Mlostoń, Arkadiusz Chworoś, Justyna Suwara, Marek J. Potrzebowski
    Academic press:
    Pharmaceutics (year: 2020, volume: 12(4), pages: 359), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics12040359 – link to the publication

Book publications / chapters in book publications (1)

  1. Fast and very fast MAS solid state NMR studies of pharmaceuticals

    Authors:
    Marta K.Dudek, SławomirKaźmierski, Marek J.Potrzebowski
    Book:
    Annual Reports on NMR Spectroscopy (year: 2021, volume: 103, pages: 97-189), Publisher: Elsevier
    Status:
    Published

« New search

Graphic design and implementation: Jakub Piotrowski