Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Reprogramming antitumor innate immunity in gliomas with osteopontin/Spp1 interfering peptides and nanovehicles-delivered siRNA/shRNA

2017/25/B/NZ3/02483

Keywords:

glioma osteopontin microg,lia nanocarriers interfering peptides

Descriptors:

  • NZ3_5:
  • NZ3_1:
  • NZ3_7:

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. Marcelego Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Aleksandra Ellert-Miklaszewska 

Number of co-investigators in the project: 5

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 996 000 PLN

Project start date (Y-m-d): 2018-01-30

Project end date (Y-m-d): 2022-01-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells
    Authors:
    Jiaxuan Chen, Aleksandra Ellert-Miklaszewska Stefano Garofalo, Arindam K. Dey, Jingjie Tang, Yifan Jiang, Flora Clément, Patrice N. Marche, Xiaoxuan Liu, Bozena Kaminska , Angela Santoni, Cristina Limatola, John J. Rossi, Jiehua Zhou and Ling Peng
    Academic press:
    Nature Protocols (rok: 2021, tom: 16, strony: 327-351), Wydawca: Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41596-020-00418-9 - link to the publication
  2. Efficient and Innocuous Delivery of Small Interfering RNA to Microglia Using an Amphiphilic Dendrimer Nanovector
    Authors:
    Ellert-Miklaszewska A, Ochocka N, Maleszewska M, Ding L, Laurini E, Jiang Y, Roura AJ, Giorgio S, Gielniewski B, Pricl S, Peng L, Kaminska B.
    Academic press:
    Nanomedicine (rok: 2019, tom: 14 (18), strony: 2441-2458), Wydawca: Future Medicine
    Status:
    Published
    DOI:
    10.2217/nnm-2019-0176 - link to the publication
  3. Integrin Signaling in Glioma Pathogenesis: From Biology to Therapy
    Authors:
    Aleksandra Ellert-Miklaszewska, Katarzyna Poleszak, Maria Pasierbinska and Bozena Kaminska
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 888), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21030888 - link to the publication
  4. 7aaRGD - a novel SPP1/integrin signaling-blocking peptide reverses immunosuppression and improves anti-PD-1 immunotherapy outcomes in experimental gliomas
    Authors:
    Aleksandra Ellert-Miklaszewska1§*, Paulina Pilanc-Kudlek1§, Katarzyna Poleszak1, Adria-Jaume Roura1, Salwador Cyranowski1, Mitrajit Ghosh1, Szymon Baluszek1, Maria Pasierbinska1, Bartłomiej Gielniewski1, Julian Swatler2, Yuliana Hovorova1, Kamil Wojnicki1, Bozena Kaminska1
    Academic press:
    Journal of Experimental and Clinical Cancer Research (rok: 2025, tom: 44 (132), strony: 45680), Wydawca: BMC - Part of Springer Nature
    Status:
    Published
    DOI:
    10.1186/s13046-025-03393-9 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy