Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Structural studies of the impact of gemini surfactants on model amyloidogenic peptides.

2016/23/N/ST5/02013

Keywords:

prion peptide cystatin peptide neurodegenerative diseases conformation

Descriptors:

  • ST5_16:
  • ST4_13:
  • NZ1_3:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Julia Maria Ludwiczak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 12 - announced on 2016-09-15

Amount awarded: 108 840 PLN

Project start date (Y-m-d): 2017-09-22

Project end date (Y-m-d): 2022-09-21

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (3)
  1. The influence of a dicationic surfactant on the aggregation process of the IVAGVN peptide derived from the human cystatin C sequence (56–61)
    Authors:
    Julia Ludwiczak, Emilia Iłowska, Michalina Wilkowska, Aneta Szymańska, Marek Kempka, Maria Dobies, Kosma Szutkowski and Maciej Kozak
    Academic press:
    RSC Advances (rok: 2025, tom: 15, strony: 3237-3249), Wydawca: Royal Society of Chemistry (United Kingdom)
    Status:
    Published
    DOI:
    10.1039/d4ra08377f. - link to the publication
  1. Structural Studies of Amyloidogenic Peptides with Cationic Gemini Imidazolium Surfactants
    Authors:
    J.Ludwiczak, M. Kozak, A. Szymanska, K.Szutkowski, M. Wilkowska
    Conference:
    Annual Meeting of Biophysical Society (rok: 2020, ), Wydawca: Biophysical Journal
    Data:
    konferencja 15 luty -19 luty
    Status:
    Published
  2. Changes in secondary structure of human prion protein peptide 30-90 induced by the presence of cationic gemini surfactant
    Authors:
    J. Ludwiczak and M. Kozak
    Conference:
    International School and Symposium on Synchrotron Radiation in Natural Science (rok: 2019, ), Wydawca: Synchrotron Radiation in Natural Science
    Data:
    konferencja 9-14 czerwca
    Status:
    Published
  3. Changes in Secondary Structure of Human Prion Protein Peptide 30-90 under the Influence of Selected Dicationic and Anionic Surfactants
    Authors:
    J. Ludwiczak , M. Kozak, , K. Szutkowski, Igor Zhukov
    Conference:
    Annual Meeting of Biophysical Society (rok: 2019, ), Wydawca: Biophysical Journal
    Data:
    konferencja 2marzec- 6 marzec
    Status:
    Published

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