Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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New class of nucelus penetrating peptides. Design, synthesis and mechanism of action

2017/27/B/ST5/02061

Keywords:

peptides peptidomimetics cell penetrating peptides breast cancer

Descriptors:

  • ST5_16:
  • NZ1_6: Synthetic biology
  • NZ5_7: Human disease treatment

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Magdalena Wysocka 

Number of co-investigators in the project: 5

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 843 000 PLN

Project start date (Y-m-d): 2018-06-14

Project end date (Y-m-d): 2021-12-13

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. uniwersalny czytnik płytek (150 000 PLN)
  2. Inkubator CO2 do hodowli komórkowej Cell Expert C170i.
  3. komora laminarna.

Information in the final report

  • Publication in academic press/journals (2)
  1. A Peptidomimetic Fluorescent Probe to Detect the Trypsin β2 Subunit of the Human 20S Proteasome
    Authors:
    Magdalena Wysocka,Anita Romanowska ,Natalia Gruba,Michalina Michalska,Artur Giełdoń, Adam Lesner
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 2396), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21072396 - link to the publication
  2. Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids
    Authors:
    Anita Romanowska,Katarzyna Węgrzyn,Katarzyna Bury,Emilia Sikorska,Aleksandra Gnatek,Agnieszka Piwkowska,Igor Konieczny,Adam Lesner, Magdalena Wysocka
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2571), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22052571 - link to the publication

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