Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of atropin in regulation of physiological function of the rat adrenal cortex

2017/25/B/NZ4/00065

Keywords:

adrenal HPA axis molecular endocrinology bioactive peptides

Descriptors:

  • NZ4_6: Endocrinology
  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marcin Ruciński 

Number of co-investigators in the project: 4

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 383 646 PLN

Project start date (Y-m-d): 2018-02-20

Project end date (Y-m-d): 2023-02-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Urządzenie do elektroporacji Gene Pulser XcellTM (39 000 PLN)
  2. Urządzenie do reakcji PCR w czasie rzeczywistym - LightCycler® 480 (185 000 PLN)
  3. komputer DELL.
  4. mikroskop z wyposażeniem.
  5. CFX96 Touch Real-Time PCR System.
  6. zamrażarka niskotemperaturowa 2860033572/Eppendorf.
  7. Dwukanałowy dyspenser do czytnika Synergy 2 (50 000 PLN)
  8. Komora Laminarna.
  9. T100Termal Cycler.
  10. wirówka Centrifuge.

Information in the final report

  • Publication in academic press/journals (4)
  1. Transcriptome Profile in Unilateral Adrenalectomy-Induced Compensatory Adrenal Growth in the Rat
    Authors:
    Karol Jopek, Marianna Tyczewska, Piotr Celichowski, Ludwik K. Malendowicz, Marcin Rucinski
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19, strony: 45308), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19041111 - link to the publication
  2. Biological response of adrenal carcinoma and melanoma cells to mitotane treatment
    Authors:
    EWELINA STELCER, HANNA KOMAROWSKA, KAROL JOPEK, AGNIESZKA ŻOK, DARIUSZ IŻYCKI, AGNIESZKA MALIŃSKA, BEATA SZCZEPANIAK, ZHANAT KOMEKBAI, MAREK KARCZEWSKI, TOMASZ WIERZBICKI, WIKTORIA MARIA SUCHORSKA, MAREK RUCHAŁA and MARCIN RUCIŃSKI
    Academic press:
    ONCOLOGY LETTERS (rok: 2022, tom: 23, strony: 45307), Wydawca: Spandidos
    Status:
    Published
    DOI:
    10.3892/ol.2022.13240 - link to the publication
  3. Immunohistochemical analysis of ghrelin expression in various types of adrenal tumors
    Authors:
    Hanna Komarowska, Agnieszka Malinska, Zhanat Komekbai, Barbara Brominska, Katarzyna Bednarek-Rajewska, Marek Ruchala, Marcin Rucinski
    Academic press:
    Folia Histochem Cytobiol. (rok: 2021, tom: 58, strony: 86-94), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/FHC.a2021.0009 - link to the publication
  4. Adropin Stimulates Proliferation and Inhibits Adrenocortical Steroidogenesis in the Human Adrenal Carcinoma (HAC15) Cell Line
    Authors:
    Ewelina Stelcer, Paulina Milecka, Hanna Komarowska, Karol Jopek, Marianna Tyczewska, Marta Szyszka, Marta Lesniczak, Wiktoria Suchorska, Karlygash Bekova, Beata Szczepaniak, Marek Ruchala, Marek Karczewski, Tomasz Wierzbicki, Witold Szaflarski, Ludwik K. Malendowicz, Marcin Rucinski
    Academic press:
    Frontiers in Endocrinology (rok: 2020, tom: 11, strony: 45311), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fendo.2020.561370 - link to the publication

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