Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Peptide conjugates as the novel antimicrobial compounds for eradication of intracellular infections and biofilm.

2016/23/D/ST5/02234

Keywords:

Antimicrobial peptides conjugates intracellular infection biofilm

Descriptors:

  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paulina Kosikowska-Adamus 

Number of co-investigators in the project: 2

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 673 880 PLN

Project start date (Y-m-d): 2017-10-02

Project end date (Y-m-d): 2022-10-01

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komora laminarna (typu BIOHAZARD) (45 000 PLN)
  2. Wytrząsarka laboratoryjna poziom (6 500 PLN)
  3. Autoklaw laboratoryjny (6 500 PLN)
  4. Oprogramowanie do celów naukowych (6 000 PLN)
  5. Mikrowirówka laboratoryjna.
  6. Inkubator z wytrząsaniem (28 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach
    Authors:
    P.Kosikowska-Adamus, E. Sikorska, D. Wyrzykowski, A. Walewska, A. Golda, M. Deptuła, M. Obuchowski, A. Prahl, A. Lesner
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(13), strony: 6679), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijm - link to the publication
  2. Electrochemical detection of bacterial endotoxin lipopolysaccharide (LPS) on gold electrode modified with DAL-PEG-DK5-PEG-OH - antimicrobial peptide conjugate
    Authors:
    Paulina Kosikowska-Adamus, Anna Golda, Jacek Ryl, Magdalena Pilarczyk-Żurek, Grzegorz Bereta, Tadeusz Ossowski, Adam Lesner, Joanna Kozieł, Adam Prahl, Paweł Niedziałkowski
    Academic press:
    Talanta , Wydawca: Talanta
    Status:
    Submitted
    DOI:
    brak - link to the publication
  3. The Bactericidal Activity of Temporin Analogues Against Methicillin Resistant Staphylococcus aureus
    Authors:
    A. Golda, P. Kosikowska-Adamus, A. Kret, O. Babyak, K. Wójcik, E. Dobosz, J. Potempa, A. Lesner, J. Kozieł
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20(19), strony: 4761), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20194761 - link to the publication
  1. Potencjał terapeutyczny peptydów przeciwdrobnoustrojowych w zwalczaniu infekcji lekoopornych oraz biofilmu
    Authors:
    Marta Makowska, Paulina Kosikowska-Adamus, Adam Prahl
    Book:
    Na pograniczu chemii i biologii (rok: 2019, tom: 39, strony: 79-92), Wydawca: Wydawnictwo Naukowe UAM
    Status:
    Published

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