Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Peptide conjugates as the novel antimicrobial compounds for eradication of intracellular infections and biofilm.

2016/23/D/ST5/02234

Keywords:

Antimicrobial peptides conjugates intracellular infection biofilm

Descriptors:

  • ST5_16:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Paulina Kosikowska-Adamus 

Number of co-investigators in the project: 2

Call: SONATA 12 - announced on 2016-09-15

Amount awarded: 673 880 PLN

Project start date (Y-m-d): 2017-10-02

Project end date (Y-m-d): 2022-10-01

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikrowirówka laboratoryjna.
  2. Wytrząsarka laboratoryjna poziom (6 500 PLN)
  3. Oprogramowanie do celów naukowych (6 000 PLN)
  4. Inkubator z wytrząsaniem (28 000 PLN)
  5. Komora laminarna (typu BIOHAZARD) (45 000 PLN)
  6. Autoklaw laboratoryjny (6 500 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Book publications / chapters in book publications (1)
  1. Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach
    Authors:
    P.Kosikowska-Adamus, E. Sikorska, D. Wyrzykowski, A. Walewska, A. Golda, M. Deptuła, M. Obuchowski, A. Prahl, A. Lesner
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(13), strony: 6679), Wydawca: MDPI
    Status:
    Published
    DOI:
  2. Electrochemical detection of bacterial endotoxin lipopolysaccharide (LPS) on gold electrode modified with DAL-PEG-DK5-PEG-OH - antimicrobial peptide conjugate
    Authors:
    Paulina Kosikowska-Adamus, Anna Golda, Jacek Ryl, Magdalena Pilarczyk-Żurek, Grzegorz Bereta, Tadeusz Ossowski, Adam Lesner, Joanna Kozieł, Adam Prahl, Paweł Niedziałkowski
    Academic press:
    Talanta , Wydawca: Talanta
    Status:
    Submitted
  3. The Bactericidal Activity of Temporin Analogues Against Methicillin Resistant Staphylococcus aureus
    Authors:
    A. Golda, P. Kosikowska-Adamus, A. Kret, O. Babyak, K. Wójcik, E. Dobosz, J. Potempa, A. Lesner, J. Kozieł
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20(19), strony: 4761), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20194761 - link to the publication
  1. Potencjał terapeutyczny peptydów przeciwdrobnoustrojowych w zwalczaniu infekcji lekoopornych oraz biofilmu
    Authors:
    Marta Makowska, Paulina Kosikowska-Adamus, Adam Prahl
    Book:
    Na pograniczu chemii i biologii (rok: 2019, tom: 39, strony: 79-92), Wydawca: Wydawnictwo Naukowe UAM
    Status:
    Published