Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The study of self-assembly of antimicrobial lipopeptides and their effects on model membranes.

2016/21/B/ST5/01375

Keywords:

antimicrobial peptides lipopeptides surfactants micelles peptide-membrane interactions

Descriptors:

  • ST5_16:
  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Gdański, Wydział Chemii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Emilia Sikorska 

Number of co-investigators in the project: 7

Call: OPUS 11 - announced on 2016-03-15

Amount awarded: 627 180 PLN

Project start date (Y-m-d): 2017-01-18

Project end date (Y-m-d): 2020-01-17

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Tensjometr (180 000 PLN)
  2. Termostat.
  3. Termowytrząsarka (7 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Double-Headed Cationic Lipopeptides: An Emerging Class of Antimicrobials
    Authors:
    Izabela Małuch, Oktawian Stachurski, Paulina Kosikowska-Adamus, Marta Makowska, Marta Bauer, Dariusz Wyrzykowski, Aleksandra Hać, Wojciech Kamysz, Milena Deptuła, Michał Pikuła, Emilia Sikorska
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 8944), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21238944 - link to the publication
  2. Short arginine-rich lipopeptides: From self-assembly to antimicrobial activity
    Authors:
    Emilia Sikorska, Oktawian Stachurski, Damian Neubauer, Izabela Małuch, Dariusz Wyrzykowski, Marta Bauer, Krzysztof Brzozowski, Wojciech Kamysz
    Academic press:
    BBA - Biomembranes (rok: 2018, tom: 1860 (11), strony: 2242-2251), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2018.09.004 - link to the publication
  3. Effect of self-assembly on antimicrobial activity of double-chain short cationic lipopeptides
    Authors:
    Oktawian Stachurski, Damian Neubauer, Izabela Małuch, Dariusz Wyrzykowski, Marta Bauer, Sylwia Bartoszewska, Wojciech Kamysz, Emilia Sikorska
    Academic press:
    Bioorganic & Medicinal Chemistry (rok: 2019, tom: 27, strony: 115129), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bmc.2019.115129 - link to the publication
  1. Double-head lipopeptide surfactants as potential antimicrobial agents
    Authors:
    Izabela Małuch, Oktawian Stachurski, Paulina Kosiowska-Adamus, Dariusz Wyrzykowski, Adam Prahl, Emilia Sikorska
    Conference:
    35th European Peptide Symposium (rok: 2018, ), Wydawca: European Peptide Society
    Data:
    konferencja 26-31.08
    Status:
    Published