Projects funded by the NCN

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253 projects found matching your search criteria :

  1. Computational alchemy and experimental validation: a hybrid approach for designing new antimicrobial peptides

    Call: PRELUDIUM 22 , Panel: NZ1

    Principal investigator: Piotr Maciej Chyży

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  2. Epigenetic biomarkers of destruction of residual beta cells after diagnosis of type 1 diabetes – links to diabetic ketoa...

    Call: PRELUDIUM 22 , Panel: NZ5

    Principal investigator: Arkadiusz Mariusz Michalak

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  3. Conjugates of peptide nucleic acids with aminoglycosides and fluoroquinolones as a novel strategy to target multi-drug r...

    Call: PRELUDIUM 22 , Panel: ST5

    Principal investigator: Izabela Siekierska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  4. Research on the preparation of new, hydrogel nanosystems for targeted therapy of colorectal cancer

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Urszula Helena Piotrowska

    Warszawski Uniwersytet Medyczny

  5. Retro-inverso strategy as a way to enhance the antimicrobial activity of clavanin complexes

    Call: PRELUDIUM BIS 4 , Panel: ST4

    Principal investigator: dr hab. Magdalena Alina Rowińska-Żyrek

    Uniwersytet Wrocławski, Wydział Chemii

  6. Identification of key structural elements of immunomodulatory proteins - inhibitors of antigenic peptide transporter TAP...

    Call: SONATA 18 , Panel: NZ7

    Principal investigator: dr Natalia Anna Karska

    Uniwersytet Gdański, Wydział Chemii

  7. Biological membranes and macromolecular crowding in the function of the hepatitis C virus proteases

    Call: PRELUDIUM BIS 4 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  8. Anticancer drug candidates from Nostoc edaphicum CCNP1411 and Pseudanabaena galeata CCNP1313 (CYANOCRAB)

    Call: OPUS 23 , Panel: NZ9

    Principal investigator: prof. Hanna Jurata Mazur-Marzec

    Uniwersytet Gdański, Wydział Chemii

  9. N-terminally truncated albumin: friend or foe of copper metabolism?

    Call: PRELUDIUM 21 , Panel: ST4

    Principal investigator: Marta Dorota Wiśniewska

    Instytut Biochemii i Biofizyki PAN

  10. Bionanoparticles with a molecular targeting device as a weapon for breast cancer

    Call: OPUS 23 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  11. Proinsulin C-peptide and G protein-coupled receptor 146 (GPR146) – clinical investigation of the impact of their signall...

    Call: PRELUDIUM 21 , Panel: NZ4

    Principal investigator: Aleksandra Ryk

    Uniwersytet Medyczny w Łodzi, Wydział Lekarski

  12. Peptide receptor complexes for auxin canalization and regeneration in Arabidopsis.

    Call: OPUS 22 (LAP) , Panel: NZ1

    Principal investigator: dr Ewa Mazur

    UNIWERSYTET ŚLĄSKI, Wydział Nauk Przyrodniczych

  13. The effect of milk-clotting enzymes from Jiuqu microbes on coagulation and quality developing mechanisms of cheese

    Call: OPUS 22 , Panel: NZ9

    Principal investigator: dr hab. Justyna Żulewska

    Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Nauki o Żywności

  14. Blocking interactions between Rab1b and Rab5 proteins and their negative regulators TBC1D20 and TBC1D17 with synthetic p...

    Call: PRELUDIUM BIS 3 , Panel: NZ1

    Principal investigator: dr hab. Edyta Violetta Gendaszewska-Darmach

    Politechnika Łódzka, Wydział Biotechnologii i Nauk o Żywności

  15. SELECTIVE REGULATION OF RAB GTPASES BY TARGETING PROTEIN-PROTEIN INTERACTIONS BETWEEN RABS AND REGULATORY PROTEINS

    Call: PRELUDIUM BIS 3 , Panel: ST4

    Principal investigator: dr hab. Katarzyna Magdalena Błażewska

    Politechnika Łódzka, Wydział Chemiczny

  16. De novo design of cavity-incorporating mini-proteins and their application in catalysis

    Call: OPUS 22 , Panel: ST4

    Principal investigator: prof. Łukasz Berlicki

    Politechnika Wrocławska

  17. Multi-scale method for amyloid fibril assembly using protofilament structures predicted by coarse-grained docking simula...

    Call: OPUS 22 , Panel: NZ2

    Principal investigator: dr Michał Koliński

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  18. New approach to the treatment of Alzheimer's disease targetingresolution of inflammation and modulation of biomechanical...

    Call: OPUS 22 , Panel: NZ4

    Principal investigator: prof. Agnieszka Basta-Kaim

    Instytut Farmakologii PAN

  19. Identification of low molecular weight compounds and peptides with high biological activity present in maggot secretions...

    Call: SONATA 17 , Panel: NZ7

    Principal investigator: dr Katarzyna Joanna Papaj

    Politechnika Śląska, Centrum Biotechnologii

  20. Inhibiting the Mitochondrial Intermembrane Space Assembly pathway as a newapproach to prevent metabolic reprogramming of...

    Call: OPUS 22 , Panel: NZ5

    Principal investigator: dr hab. Carlo Vascotto

    Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

  21. Coming out of the shadow of iron – manganese as an important player at the host-pathogen interface.

    Call: SONATA 17 , Panel: ST4

    Principal investigator: dr Małgorzata Ostrowska

    Uniwersytet Wrocławski, Wydział Chemii

  22. CRISPRi-based screening for Pseudomonas aeruginosa vulnerabilities to antibiotics

    Call: SONATA 17 , Panel: NZ2

    Principal investigator: dr Adam Kawałek

    Instytut Biochemii i Biofizyki PAN

  23. Dependence of growth of young pig from protein qualitative digestion - peptide vs. amino acid absorption

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Kamil Krzysztof Zaworski

    Instytut Fizjologii i Żywienia Zwierząt im. Jana Kielanowskiego PAN

  24. New Thrombospondin-1-deriving Peptides as TGF-β Activators of Cosmeceutical Interest

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Patrycja Dominika Ledwoń

    Politechnika Wrocławska

  25. Small, well-armed fighters vs. powerful, devastating enemies - modified peptidecomplexes from human saliva in the fight ...

    Call: OPUS 21 , Panel: ST4

    Principal investigator: dr Joanna Małgorzata Wątły

    Uniwersytet Wrocławski, Wydział Chemii

  26. In the search of new insecticides: immunomodulatory role of tachykinin-related peptides and their potential usage in pes...

    Call: OPUS 21 , Panel: NZ9

    Principal investigator: dr Arkadiusz Urbański

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

  27. Design of metal-peptide complexes based on amyloid β sequence with a His-2 binding motif as selective receptors in elect...

    Call: PRELUDIUM 20 , Panel: ST4

    Principal investigator: Aleksandra Magdalena Tobolska

    Politechnika Warszawska

  28. Potential neuroprotective properties of modulators of sphingosine-1-phosphate (S1P) receptors (fingolimod and siponimod)...

    Call: PRELUDIUM 20 , Panel: NZ5

    Principal investigator: Iga Wieczorek

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  29. Antiviral strategies targeting RNA: Triplex forming peptide nucleic acids (PNA) and their small molecule conjugates spec...

    Call: OPUS 21 , Panel: NZ1

    Principal investigator: prof. Elżbieta Beata Kierzek

    Instytut Chemii Bioorganicznej PAN

  30. Blocking the TNF-TNFR2 interactions as a novel approach to the ovarian carcinoma treatment

    Call: OPUS 21 , Panel: NZ7

    Principal investigator: prof. Sylwia Anna Rodziewicz-Motowidło

    Uniwersytet Gdański, Wydział Chemii

  31. Characterization of bioactive peptides from chicken feather keratin and products of their transformations occurring duri...

    Call: PRELUDIUM 20 , Panel: NZ9

    Principal investigator: Antoni Taraszkiewicz

    Politechnika Gdańska

  32. Mechanisms of host-pathogen interaction in the immune response of Galleria mellonella after infection with entomopathoge...

    Call: OPUS 1 , Panel: NZ6

    Principal investigator: dr hab. Iwona Elżbieta Wojda

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  33. Blocking HVEM/LIGHT interactions using peptides - an innovative approach to immunosuppression

    Call: PRELUDIUM BIS 2 , Panel: ST4

    Principal investigator: dr hab. Adam Kazimierz Sieradzan

    Uniwersytet Gdański, Wydział Chemii

  34. Development of tools for the rational design of peptide therapeutics

    Call: OPUS 20 , Panel: NZ2

    Principal investigator: dr hab. Sebastian Kmiecik

    Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

  35. Dissecting cancer activome to develop new generation of antibody-drug conjugates

    Call: OPUS 20 (LAP) , Panel: NZ5

    Principal investigator: dr hab. Marcin Łukasz Poręba

    Politechnika Wrocławska

  36. Synthesis and evaluation of PD-L1 inhibitors based on mixed mode scaffolds containing amino acid derivatives, short pept...

    Call: SONATA 16 , Panel: ST4

    Principal investigator: dr Ewa Maria Surmiak

    Uniwersytet Jagielloński, Wydział Chemii

  37. The influence of environment on biomolecular function, structure and interactions.

    Call: SONATA BIS 10 , Panel: ST4

    Principal investigator: dr hab. Piotr Mikołaj Setny

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  38. The role of MOTS-c peptide in the regulation of adrenal cortex physiological function

    Call: SONATA BIS 10 , Panel: NZ4

    Principal investigator: prof. Marcin Michał Ruciński

    Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

  39. In solution or in the membrane? Determination of partition of beta-amyloid peptides between the water and phospholipid p...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: prof. Wojciech Bal

    Instytut Biochemii i Biofizyki PAN

  40. Studies over the dissociation of peptides in non-aqueous enviroments and the development of a universal counter-ion exch...

    Call: OPUS 2 , Panel: NZ7

    Principal investigator: dr hab. Wojciech Kamysz

    Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

  41. Direct monitoring of the local dynamic rearrangement of the Alzheimer's peptides secondary structure upon the aggregatio...

    Call: OPUS 19 , Panel: ST4

    Principal investigator: dr hab. Ewelina Lipiec

    Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

  42. Making use of siderophore transport systems to deliver peptide nucleic acids to bacterial cells

    Call: OPUS 19 , Panel: NZ1

    Principal investigator: prof. Joanna Dominika Trylska

    Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

  43. Modulation of molecular pathways by pharmacological mitochondria-targeting hydrogen sulfide donor in chronic gastric ulc...

    Call: PRELUDIUM 19 , Panel: NZ4

    Principal investigator: dr Dagmara Ewa Wójcik-Grzybek

    Uniwersytet Jagielloński, Collegium Medicum

  44. Bioactive compounds in the immune response of Galleria mellonella infected with the entomopathogenic bacterium Pseudomon...

    Call: OPUS 19 , Panel: NZ6

    Principal investigator: dr hab. Iwona Elżbieta Wojda

    Uniwersytet Marii Curie-Skłodowskiej w Lublinie, Wydział Biologii i Biotechnologii

  45. A peptidomimetic strategy to improve the antimicrobial properties of calcitermin

    Call: PRELUDIUM 19 , Panel: ST4

    Principal investigator: Denise Bellotti

    Uniwersytet Wrocławski, Wydział Chemii

  46. Structural studies of the influence of selected surfactants on the amyloidogenic properties of various forms of beta pep...

    Call: ETIUDA 8 , Panel: ST4

    Principal investigator: Michalina Maria Wilkowska

    Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Fizyki

  47. Novel role of peroxisome proliferator-activated receptor α in the regulationof amyloid β peptide metabolism and mitochon...

    Call: PRELUDIUM 18 , Panel: NZ4

    Principal investigator: dr Sylwia Żulińska

    Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

  48. Application of N-(2-thioethyl)glycine analogues in orthogonal cleavage of peptides from solid support

    Call: PRELUDIUM 18 , Panel: ST4

    Principal investigator: Magdalena Elżbieta Wierzbicka

    Uniwersytet Wrocławski, Wydział Chemii

  49. Novel analogs of human cathelicidin (LL-37) with enhanced resistant to enzymatic degradation. Design chemical synthesis ...

    Call: PRELUDIUM BIS 1 , Panel: ST4

    Principal investigator: prof. Adam Jerzy Lesner

    Uniwersytet Gdański, Wydział Chemii

  50. Insulin – metallacarborane conjugates: A new strategy to enhance the biological efficacy of peptide drugs

    Call: PRELUDIUM BIS 1 , Panel: NZ7

    Principal investigator: dr hab. Tomasz Marek Goszczyński

    Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

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