Search results

101. The role of halogen bonding in interaction of ligands with SERT.

Principal investigator: dr Jakub Staroń

Instytut Farmakologii PAN

Call: SONATA 11, Panel: NZ7

102. Modulation of amygdala neural network activity by the 5-HT7 receptor

Principal investigator: prof. Krzysztof Tokarski

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ4

103. The role of the endogenuous opioid system in prosocial behavior

Principal investigator: dr hab. Jan Manuel Rodriguez Parkitna

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ4

104. Maternal diet during gestation and nutrition as a risk factor for cocaine use disorder in offspring - preclinical behavi…

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ4

105. Pharmacological properties and neurotoxicity of novel NBOMe derivatives

Principal investigator: prof. Krystyna Czesława Gołembiowska

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ7

106. Effects of chosen chemokines on the activity and synaptic transmission in central and basolateral complex of the amygdal…

Principal investigator: Joanna Ewa Sowa

Instytut Farmakologii PAN

Call: PRELUDIUM 11, Panel: NZ4

107. Characterisation of the orbitofrontal cortex dopamine D1 and D2 receptors' influence on rat's cognitive flexibility and …

Principal investigator: Michał Dariusz Rychlik

Instytut Farmakologii PAN

Call: PRELUDIUM 11, Panel: NZ4

108. Development of protocol for in silico design of compounds inhibit Ebola virus infection

Principal investigator: Dawid Zdzisław Warszycki

Instytut Farmakologii PAN

Call: PRELUDIUM 11, Panel: NZ2

109. Search for new targets for an effective therapy of neuropathic pain and enhancement of opioids effects basing on the exa…

Principal investigator: prof. Joanna Gabriela Mika

Instytut Farmakologii PAN

Call: OPUS 11, Panel: NZ4

110. Fingerprint Połączeń Podstrukturalnych - nowa metoda reprezentacji związków chemicznych

Principal investigator: Krzysztof Rataj

Instytut Farmakologii PAN

Call: ETIUDA 4, Panel: NZ2

111. Adaptacyjne podejmowanie decyzji u zwierząt z komórkowo specyficzną inaktywacją receptorów glutaminianu w układzie dopam…

Principal investigator: Przemysław Eligiusz Cieślak

Instytut Farmakologii PAN

Call: ETIUDA 4, Panel: NZ4

112. Neurodevelopmental patomechanisms of triclocarban- and dichlorodiphenyldichloroetylene-induced effects: the role of apop…

Principal investigator: dr hab. Małgorzata Kajta

Instytut Farmakologii PAN

Call: OPUS 10, Panel: NZ7

113. The role of selected signaling pathways in zinc deficiency

Principal investigator: prof. Gabriel Piotr Nowak

Instytut Farmakologii PAN

Call: OPUS 10, Panel: NZ4

114. The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopola…

Principal investigator: Karolina Sylwia Podkowa

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ7

115. The role of the neuron-microglia CX3CL1-CX3CR1 and CD200-CD200R protein systems in molecular mechanisms of antipsychotic…

Principal investigator: prof. Agnieszka Basta-Kaim

Instytut Farmakologii PAN

Call: OPUS 10, Panel: NZ7

116. Molecular mechanism of interactions between GPCRs and G protein.

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii PAN

Call: PRELUDIUM 10, Panel: NZ2

117. A virtual screening protocol based on automatically generated structure-based pharmacophore models.

Principal investigator: Stefan Mateusz Mordalski

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ2

118. Searching for the new lead structures for 5-HT7 serotonin receptor ligands with increased metabolic stability.

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: HARMONIA 7, Panel: NZ7

119. Substructural Connectivity Fingerprint and Extreme Entropy Machines: A New Method of Compound Representation and Analysi…

Principal investigator: Krzysztof Rataj

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: ST6

120. The role of microRNA biogenesis system in vulnerability and resilience to stress in an animal model of depression

Principal investigator: Dariusz Marek Żurawek

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: NZ4

121. Functional dissection of three alpha(1)-adrenergic receptor subtypes in the effects of antidepressant drugs: exploitatio…

Principal investigator: prof. Irena Maria Nalepa

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

122. Investigation of the effects and mechanisms of action of Deep Brain Stimulation in two animal models of treatment-resist…

Principal investigator: prof. Mariusz Papp

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

123. Changes in neurogenesis during withdrawal from nicotine self-administration in rats - role of serotonin (5-HT)2C recepto…

Principal investigator: dr Magdalena Joanna Zaniewska

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ4

124. Role of the NLRP3 inflammasome in the mechanisms of action of antidepressant drugs - study in an animal model of depress…

Principal investigator: dr Ewa Izabela Trojan

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: NZ7

125. Effects of prenatal stress on properities of neurons and synaptic transmission in dorsal raphe nucleus of the rat

Principal investigator: Joanna Grażyna Sowa

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: NZ4

126. Simultaneous stimulation of muscarinic M4 receptor and selected receptors involved in the regulation of glutamate releas…

Principal investigator: dr hab. Joanna Monika Wierońska

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

127. Altered interaction between NMDA receptor subunits and their scaffolding proteins as a critical step to control drug see…

Principal investigator: prof. Małgorzata Maria Filip

Instytut Farmakologii PAN

Call: OPUS 9, Panel: NZ7

128. The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on pre…

Principal investigator: Iwona Magdalena Majcher-Maślanka

Instytut Farmakologii PAN

Call: PRELUDIUM 9, Panel: NZ4

129. The role of kynurenine pathway in neurophatic pain in view of innovative treatment approaches

Principal investigator: dr Ewelina Joanna Rojewska

Instytut Farmakologii PAN

Call: SONATA 9, Panel: NZ4

130. Wykorzystanie metod uczenia maszynowego w zadaniach komputerowo wspomaganego projektowania leków.

Principal investigator: Sabina Marta Podlewska

Instytut Farmakologii PAN

Call: ETIUDA 3, Panel: NZ2

131. Znaczenie interakcji układu endokanabinoidowego i endowaniloidowego w leczeniu bólu przewlekłego - potencjał terapeutycz…

Principal investigator: Natalia Eleonora Małek

Instytut Farmakologii PAN

Call: ETIUDA 3, Panel: NZ7

132. Molecular mechanism of unique action of clozapine in the context of GPCR.

Principal investigator: dr Agata Faron-Górecka

Instytut Farmakologii PAN

Call: OPUS 8, Panel: NZ7

133. Neural substrates of decision making under risk and uncertainty: role of phasic activity of dopamine neurons

Principal investigator: Przemysław Eligiusz Cieślak

Instytut Farmakologii PAN

Call: PRELUDIUM 8, Panel: NZ4

134. The effects of ligands of the alpha7 nicotinic acetylcholine receptors on complex cognitive processes and social behavio…

Principal investigator: Agnieszka Teresa Potasiewicz

Instytut Farmakologii PAN

Call: PRELUDIUM 8, Panel: NZ7

135. The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CY…

Principal investigator: Agnieszka Basińska-Ziobroń

Instytut Farmakologii PAN

Call: PRELUDIUM 8, Panel: NZ7

136. Halogen bonding - the role and significance in interactions of ligands with class A GPCRs

Principal investigator: dr Rafał Kurczab

Instytut Farmakologii PAN

Call: SONATA 8, Panel: NZ7

137. Unusual 5-HT6 receptor ligands

Principal investigator: prof. Andrzej Jacek Bojarski

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

138. Neurotoxic effects of benzophenone-3 : the role of estrogen receptors and retinoid X receptor alpha.

Principal investigator: Agnieszka Wnuk

Instytut Farmakologii PAN

Call: PRELUDIUM 7, Panel: NZ4

139. The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

Principal investigator: prof. Bogusława Budziszewska

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

140. Targeting peripheral cannabinoid receptors CB2 as a novel therapy to treat osteoarthritis

Principal investigator: dr hab. Katarzyna Maria Starowicz-Bubak

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

141. The effect of social stress during adolescence on the psychotic symptoms development and epigenetic mechanisms in the ne…

Principal investigator: dr hab. Marzena Małgorzata Maćkowiak

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ4

142. Molecular mechanism of action of antidepressant drugs in the in vitro model of contact allergy in the human cell line Ha…

Principal investigator: Katarzyna Curzytek

Instytut Farmakologii PAN

Call: PRELUDIUM 7, Panel: NZ6

143. Pessimism as cognitive biomarker of depression in animal model

Principal investigator: dr hab. Rafał Ryguła

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ4

144. The impact of maternal diabetes on inflammasome NLRP3 activation in the offspring brain

Principal investigator: dr Katarzyna Elżbieta Głombik

Instytut Farmakologii PAN

Call: PRELUDIUM 7, Panel: NZ7

145. Involvement of cyclooxygenase 2 in antidepressant-like effects of metabotropic glutamatergic receptors group I.

Principal investigator: dr Katarzyna Małgorzata Stachowicz

Instytut Farmakologii PAN

Call: SONATA 7, Panel: NZ7

146. Evaluation of the role of transcription factor CREB in the mechanisms antidepressant treatment: study on the novel genet…

Principal investigator: dr Grzegorz Kreiner

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

147. Research of mechanisms of antidepressant action of group II and III mGlu receptor ligands and their role in inducing rap…

Principal investigator: dr hab. Agnieszka Pałucha-Poniewiera

Instytut Farmakologii PAN

Call: OPUS 7, Panel: NZ7

148. Noradrenergic modulation of cocaine-seeking

Principal investigator: dr Wojciech Barnaba Solecki

Instytut Farmakologii PAN

Call: SONATA 6, Panel: NZ4

149. The effect of the novel atypical neuroleptics on the activity and expression of cytochrome P450 isoforms in human liver

Principal investigator: dr hab. Jacek Wójcikowski

Instytut Farmakologii PAN

Call: OPUS 6, Panel: NZ7

150. Evaluation of histopathological changes in the rats tissues after acute and chronic administration of the compounds from…

Principal investigator: Edyta Dorota Możdżeń

Instytut Farmakologii PAN

Call: PRELUDIUM 6, Panel: NZ7

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