The effect of typical and atypical neuroleptics on the expression of cytochrome P450 isoenzymes 1A2 (CYP1A2) and 3A4 (CYP3A4) in human hepatocytes.
2014/15/N/NZ7/02955
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Instytut Farmakologii PAN
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 8 – announced on 2014-09-15
- Amount awarded
- 99 960 PLN
- Project start date
- 2015-09-02
- Project end date
- 2018-07-01
- Project duration
- 34 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (1)
-
Levomepromazine and clozapine induce the main human cytochrome P450 drug metabolizing enzyme CYP3A4
- Authors:
- Danek P.J., Basińska-Ziobroń A., Wójcikowski J., Daniel W.A.
- Academic press:
- Pharmacological Reports (year: 2020, volume: -, pages: -), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1007/s43440-020-00157-4 – link to the publication
Articles in post-conference publications (1)
-
Clozapine and levomepromazine induce the cytochrome P450 isoenzyme CYP3A4, but not CYP1A1/2, in human hepatocytes
- Authors:
- Danek P., Basińska-Ziobroń A., Daniel W.A., Wójcikowski J.
- Conference:
- 30th ECNP Congress, Paris, France (year: 2017, pages: S927), Publisher: Elsevier
- Date:
- conference 2-5 wrzesień
- Status:
- Published
- DOI:
- link to the publication