Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The effect of the metabotropic glutamatergic receptor ligands on potentiating the antidepressant-like actvity of scopolamine in animal models.

2015/19/N/NZ7/01632

Keywords:

glutamate scopolamine mGlu receptors antidepressant drugs

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii im. Jerzego Maja Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Karolina Podkowa 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-09-29

Project end date (Y-m-d): 2019-09-28

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (1)
  1. The potential antidepressant action and adverse effects profile of scopolamine co-administered with the mGlu7 receptor allosteric agonist AMN082 in mice
    Authors:
    Podkowa Karolina, Pilc Andrzej, Podkowa Adrian, Sałat Kinga, Marciniak Marcin, Pałucha-Poniewiera Agnieszka
    Academic press:
    Neuropharmacology (rok: 2018, tom: 141, strony: 214-222), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuropharm.2018.08.022 - link to the publication
  1. AMN082, a positive allosteric modulator of the mGlu7 receptor, enhances the antidepressant-like activity of scopolamine in the tail suspension test
    Authors:
    Karolina Podkowa, Adrian Podkowa, Kinga Sałat, Andrzej Pilc, Agnieszka Pałucha-Poniewiera
    Conference:
    30th ECNP Congress, Paris, France (rok: 2017, ), Wydawca: European Neuropsychopharmacology, Volume 27, Supplement 4
    Data:
    konferencja 2-5.09.2017
    Status:
    Published

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