The impact of maternal diabetes on inflammasome NLRP3 activation in the offspring brain

2014/13/N/NZ7/00279

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia
  • NZ4_9: Neurobiologia systemowa
  • NZ4_11: Metabolizm

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Elżbieta Głombik

Number of co-investigators in the project: 3

Call

PRELUDIUM 7 – announced on 2014-03-17

Amount awarded
149 786 PLN
Project start date
2015-02-20
Project end date
2018-08-19
Project duration
42 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (1)

  1. Inflammatory Consequences of Maternal Diabetes on the Offspring Brain: a Hippocampal Organotypic Culture Study.

    Authors:
    Katarzyna Głombik, Ewa Trojan, Anna Kurek, Bogusława Budziszewska, Agnieszka Basta-Kaim
    Academic press:
    Neurotoxicity Research (year: 2019, volume: brak, pages: Epub ahead of print), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12640-019-00070-6 – link to the publication

Articles in post-conference publications (5)

  1. Glyburide prevents inflammatory factors release in the brain of diabetic dams offspring : new benefits of anti-diabetes drugs treatment

    Authors:
    Głombik Katarzyna, Trojan Ewa, Kurek Anna, Ślusarczyk Joanna, Chamera Katarzyna, Basta-Kaim Agnieszka
    Conference:
    XI Copernican International Young Scientists Conference (year: 2017, pages: 76), Publisher: Faculty of Chemistry, Nicolaus Copernicus University in Toruń, Poland
    Date:
    conference 28-30.06
    Status:
    Published
  2. Regulation of NLRP3 inflammasome gene expression in the hippocampus by maternal diabetes

    Authors:
    Katarzyna Głombik, Ewa Trojan, Anna Kurek, Bogusława Budziszewska, Agnieszka Basta-Kaim
    Conference:
    NEURONUS 2018 IBRO Neuroscience Forum (year: 2018, pages: 64-65), Publisher: Neuronus Forum
    Date:
    conference 20-22.04
    Status:
    Published
  3. The beneficial effect of glyburide on the evoked by maternal diabetes changes in the offspring brain

    Authors:
    Katarzyna Głombik, Ewa Trojan, Anna Kurek, Joanna Ślusarczyk, Katarzyna Chamera, Agnieszka Basta-Kaim
    Conference:
    12th EFIS-EJI Tatra Immunology Conference, Strebskie Pleso (year: 2016, pages: -), Publisher: European Federation of Immunological Societies, Eureopean Journal of Immunology
    Date:
    conference 3-7.09
    Status:
    Published
  4. Influence of metformin on the maternal diabetes-induced changes in the hippocampus of rat offspring

    Authors:
    Katarzyna Głombik, Ewa Trojan, Anna Kurek, Joanna Ślusarczyk, Agnieszka Basta-Kaim
    Conference:
    NEURONUS 2016 IBRO & IRUN Neuroscience Forum (year: 2016, pages: 75-76), Publisher: Neuronus Forum
    Date:
    conference 22-24.04
    Status:
    Published
    DOI:
    link to the publication
  5. The impact of maternal diabetes on apoptotic and inflammatory processes in the offspring brain

    Authors:
    Katarzyna Głombik, Ewa Trojan, Anna Kurek, Joanna Ślusarczyk, Katarzyna Chamera, Agnieszka Basta-Kaim
    Conference:
    XXX Ogólnopolskie Seminarium pt. Mechanizmy służące utrzymaniu życia i regulacji fizjologicznych (year: 2016, pages: 105-106), Publisher: Małopolska Wyższa Szkoła im. Józefa Dietla w Krakowie
    Date:
    conference 25,06
    Status:
    Published

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