Znaczenie interakcji układu endokanabinoidowego i endowaniloidowego w leczeniu bólu przewlekłego - potencjał terapeutyczny związków hybrydowych.

2015/16/T/NZ7/00052

Descriptors

  • NZ7_12: Prewencja chorób człowieka
  • NZ7_14: Farmacja, farmakoterapia, farmakologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Natalia Eleonora Małek

Number of co-investigators in the project: 2

Call

ETIUDA 3 – announced on 2014-12-15

Amount awarded
108 576 PLN
Project start date
2015-10-01
Project end date
2016-08-31
Project duration
11 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (3)

  1. Sex differences in peripheral not central immune responses to pain-inducing injury

    Authors:
    Lopes DM*, Malek N*, Edye M, Jager SB, McMurray S, McMahon SB, Denk F (*equal contribution)
    Academic press:
    Scientific Reports (year: 2017, volume: 7:16460, pages: brak), Publisher: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-017-16664-z – link to the publication
  2. The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain.

    Authors:
    Malek N, Kostrzewa M, Makuch W, Pajak A, Kucharczyk M, Piscitelli F, Przewlocka B, Di Marzo V, Starowicz K
    Academic press:
    Pharmacological Research (year: 2016, volume: 111, pages: 251-63), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.phrs.2016.06.012 – link to the publication
  3. Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems-A Novel Treatment Option for Chronic Pain Management.

    Authors:
    Malek N, Starowicz K
    Academic press:
    Frontiers in pharmacology (year: 2016, volume: brak, pages: brak), Publisher: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fphar.2016.00257 – link to the publication

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Graphic design and implementation: Jakub Piotrowski