Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of the factors involved in the brain glucose metabolism in the model of obesity and depression comorbidity

2014/13/B/NZ7/02278

Keywords:

depression obesity glucocorticoids insulin glucogon-like peptide-1 glucose metabolism brain

Descriptors:

  • NZ7_4: Prevention in population health
  • NZ4_8: Neuroendocrinology
  • NZ3_6: Cell neurobiology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Bogusława Budziszewska 

Number of co-investigators in the project: 7

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 707 069 PLN

Project start date (Y-m-d): 2015-01-23

Project end date (Y-m-d): 2018-04-22

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Aparat do elektroforezy poziomej DNA z zasilaczem (5 500 PLN)
  2. Spektrofotometr NanoDrop™ Lite (32 000 PLN)
  3. Transiluminator UV (2 500 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (4)
  1. Brain metabolic alterations in rats showing depression-like and obesity phenotypes
    Authors:
    Katarzyna Głombik, Jan Detka, Joanna Góralska, Anna Kurek, Bogdan Solnica, Bogusława Budziszewska
    Academic press:
    Neurotoxicity Research (rok: 2019, tom: brak danych, strony: brak danych), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    10.1007/s12640-019-00131-wbrak - link to the publication
  2. Regulators of glucocorticoid receptor function in an animal model of depression and obesity
    Authors:
    Anna Kurek, Katarzyna Głombik, Jan Detka, Agnieszka Basta-Kaim, Marta Kubera, Władysław Lasoń, Bogusława Budziszewska*
    Academic press:
    Journal of Neuroendocrinology (rok: 2018, tom: 30, strony: 45304), Wydawca: WILEY
    Status:
    Published
    DOI:
    10.1111/jne.12591 - link to the publication
  3. Hypothalamic insulin and glucagon-like peptide-1 levels in an animal model of depression and their effect on corticotropin-releasing hormone promoter gene activity in a hypothalamic cell line
    Authors:
    Jan Detka, Joanna Ślusarczyk, Anna Kurek, Mateusz Kucharczyk, Tomasz Adamus, Paweł Konieczny, Marta Kubera, Agnieszka Basta-Kaim, Władysław Lasoń, Bogusława Budziszewska
    Academic press:
    Pharmacological Reports (rok: 2019, tom: 71, strony: 338-346), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2018.11.001 - link to the publication
  1. Determination of glucocorticoids action in an animal model of coexistence of depression and obesity
    Authors:
    Budziszewska B., Kurek A., Głombik K., Detka J., Basta-Kaim A.
    Conference:
    6th Mediterranean Neuroscience Society Conference 2017, Malta (rok: 2017, ), Wydawca: Journal of Malta Chamber of Scientists
    Data:
    konferencja 12-15, czerwiec 2017
    Status:
    Published
    DOI:
    link to the publication
  2. High-fat diet enhances action of prenatal stress on mineralocorticoid receptor concentration in the hippocampus.
    Authors:
    Kurek A, Detka J, Głombik K, Budziszewska B.
    Conference:
    47th Annual Meeting of International Society of Psychoneuroendocrinology 7-9.09.2017 Zurich, Szwajcaria (rok: 2017, ), Wydawca: Abstracts / Psychoneuroendocrinology 83S (2017) 1–89
    Data:
    konferencja 7-9. 09. 2017
    Status:
    Published
    DOI:
    link to the publication
  3. Brain insulin and incretin action in an animal model of obesity and depression comorbidity.
    Authors:
    Detka J., Kurek A., Głombik K., Lasoń W., Budziszewska B.
    Conference:
    10th FENS Forum of Neuroscience; July 2-6 2016, Copenhagen, Denmark. (rok: 2016, ), Wydawca: FENS Forum of Neuroscience
    Data:
    konferencja 2-6. 07.2016
    Status:
    Published
  4. The involvement of SREBP system in the pathogenesis of depression and obesity.
    Authors:
    Głombik K., Kurek A., Detka J., Budziszewska B.
    Conference:
    47th Annual Meeting of International Society of Psychoneuroendocrinology 7-9.09.2017 Zurich, Szwajcaria (rok: 2017, ), Wydawca: Abstracts / Psychoneuroendocrinology 83S (2017) 1–89
    Data:
    konferencja 07-09 wrzesień
    Status:
    Published
    DOI:
    link to the publication

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