The role of halogen bonding in interaction of ligands with SERT.
2016/21/D/NZ7/00620
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- ST5_16: Chemia biologiczna
- NZ2_7: Bioinformatyka
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Instytut Farmakologii PAN
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 4
Call
SONATA 11 – announced on 2016-03-15
- Amount awarded
- 383 500 PLN
- Project start date
- 2017-03-31
- Project end date
- 2020-03-30
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Tuning the activity of known drugs via the introduction of halogen atoms, a case study of SERT ligands – Fluoxetine and fluvoxamine
- Authors:
- Jakub Staron*, Wojciech Pietrus, Ryszard Bugno, RafałKurczab, Grzegorz Satała, Dawid Warszycki, Tomasz Lenda, Anna Wantuch, Adam S. Hogendorf, Agata Hogendorf, Beata Duszynska, Andrzej J. Bojarski
- Academic press:
- European Journal of Medicinal Chemistry (year: 2021, volume: 220, pages: 113533), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.ejmech.2021.113533 – link to the publication