Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of social stress during adolescence on the psychotic symptoms development and epigenetic mechanisms in the neurodevelopmental model of schizophrenia

2014/13/B/NZ4/00218

Keywords:

social isolation stress schizophrenia neurodevelopment MAM epigenetics neuroleptics prefrontal cortex hippocampus

Descriptors:

  • NZ4_9: Systems neurobiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marzena Maćkowiak 

Number of co-investigators in the project: 4

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 756 260 PLN

Project start date (Y-m-d): 2015-02-11

Project end date (Y-m-d): 2018-02-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Laptop wraz z podstawowym oprogramowaniem.
  2. Wytrząsarka laboratoryjna (20 000 PLN)
  3. Lażnia ultradźwiękoa (4 000 PLN)
  4. Mały autoklaw stołowy (7 000 PLN)
  5. Sterylizator kulkowy (2 000 PLN)
  6. Mieszadło magnetyczne (2 500 PLN)
  7. Termomikser (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.
    Authors:
    Marzena Maćkowiak, Joachim Latusz, Urszula Głowacka, Ewelina Bator, Wiktor Bilecki
    Academic press:
    Metabolic Brain Disease (rok: 2019, tom: 34, strony: 341-352), Wydawca: Springer Science +Business Media, LLC, part of Springer Nature 2018
    Status:
    Published
    DOI:
    10.1007/s11011-018-0359-3 - link to the publication
  2. Adolescent social isolation affects schizophrenia-like behavior in the MAM-E17 model of schizophrenia.
    Authors:
    Ewelina Bator, Joachim Latusz, Urszula Głowacka, Aleksandra Radaszkiewicz, Kinga Mudlaff, Marzena Maćkowiak
    Academic press:
    Neurotoxicity Research (rok: 2018, tom: 34, strony: 305-323), Wydawca: Springer Science+Business Media, LLC, part of Springer Nature
    Status:
    Published
    DOI:
  1. Social isolation stress during adolescence accelerates impairment of recognition memory in neurodevelopmental model of schizophrenia
    Authors:
    Maćkowiak Marzena , Bator Ewelina, Latusz Joachim, Radaszkiewicz Aleksandra, Wędzony Krzysztof
    Conference:
    10th FENS Forum of Neuroscience, Kopenhaga , Dania (rok: 2016, ), Wydawca: Programme Book,
    Data:
    konferencja 02-06 lipiec 2016 r
    Status:
    Published