The effect of social stress during adolescence on the psychotic symptoms development and epigenetic mechanisms in the neurodevelopmental model of schizophrenia

2014/13/B/NZ4/00218

Keywords

Descriptors

  • NZ4_9: Neurobiologia systemowa

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Instytut Farmakologii PAN

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marzena Małgorzata Maćkowiak

Number of co-investigators in the project: 4

Call

OPUS 7 – announced on 2014-03-17

Amount awarded
756 260 PLN
Project start date
2015-02-11
Project end date
2018-02-10
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Laptop wraz z podstawowym oprogramowaniem.
  2. Lażnia ultradźwiękoa. Cost: 4 000 PLN
  3. Mały autoklaw stołowy. Cost: 7 000 PLN
  4. Mieszadło magnetyczne. Cost: 2 500 PLN
  5. Sterylizator kulkowy. Cost: 2 000 PLN
  6. Termomikser. Cost: 25 000 PLN
  7. Wytrząsarka laboratoryjna. Cost: 20 000 PLN

Information in the final report

Publication in academic press/journals (2)

  1. Adolescent social isolation affects schizophrenia-like behavior in the MAM-E17 model of schizophrenia.

    Authors:
    Ewelina Bator, Joachim Latusz, Urszula Głowacka, Aleksandra Radaszkiewicz, Kinga Mudlaff, Marzena Maćkowiak
    Academic press:
    Neurotoxicity Research (year: 2018, volume: 34, pages: 305-323), Publisher: Springer Science+Business Media, LLC, part of Springer Nature
    Status:
    Published
    DOI:
    10.1007/s – link to the publication
  2. Adolescent social isolation affects parvalbumin expression in the medial prefrontal cortex in the MAM-E17 model of schizophrenia.

    Authors:
    Marzena Maćkowiak, Joachim Latusz, Urszula Głowacka, Ewelina Bator, Wiktor Bilecki
    Academic press:
    Metabolic Brain Disease (year: 2019, volume: 34, pages: 341-352), Publisher: Springer Science +Business Media, LLC, part of Springer Nature 2018
    Status:
    Published
    DOI:
    10.1007/s11011-018-0359-3 – link to the publication

Articles in post-conference publications (1)

  1. Social isolation stress during adolescence accelerates impairment of recognition memory in neurodevelopmental model of schizophrenia

    Authors:
    Maćkowiak Marzena , Bator Ewelina, Latusz Joachim, Radaszkiewicz Aleksandra, Wędzony Krzysztof
    Conference:
    10th FENS Forum of Neuroscience, Kopenhaga , Dania (year: 2016, pages: 3540), Publisher: Programme Book,
    Date:
    conference 02-06 lipiec 2016 r
    Status:
    Published

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