Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The impact of early-life stress (maternal separation) and fluctuation in corticosterone levels during adolescence on prefrontal cortex plasticity and functions.

2015/17/N/NZ4/02800

Keywords:

early-life stress maternal separation medial prefrontal cortex adolescence corticosterone synaptic plasticity glia mood disorders anxiety LTP

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_5: Anatomical pathology
  • NZ4_4: Pathophysiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Farmakologii PAN

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Iwona Majcher-Maślanka 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 149 964 PLN

Project start date (Y-m-d): 2016-03-16

Project end date (Y-m-d): 2019-03-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wytrząsarka do płytek laboratoryjnych z kontrolą temperatury (4 200 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Previous Early-life Stress Modifies Acute Corticosterone-induced Synaptic Plasticity in the Medial Prefrontal Cortex of Adolescent Rats.
    Authors:
    I. Majcher-Maślanka, A. Solarz, K. Wędzony, A. Chocyk
    Academic press:
    Neuroscience (rok: 2018, tom: 379, strony: 316-333), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.neuroscience.2018.03.038 - link to the publication
  2. The impact of early-life stress on corticosteroid carrier protein levels and 11β-hydroxysteroid dehydrogenase 1 expression in adolescent rats.
    Authors:
    I. Majcher-Maślanka, A. Solarz, A. Chocyk
    Academic press:
    Pharmacological Reports (rok: 2019, tom: 71, strony: 347-350), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2018.11.003 - link to the publication
  3. Maternal separation disturbs postnatal development of the medial prefrontal cortex and affects the number of neurons and glial cells in adolescent rats.
    Authors:
    I. Majcher-Maślanka, A. Solarz, A. Chocyk
    Academic press:
    Neuroscience (rok: 2019, tom: 423, strony: 131-147), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.033 - link to the publication
  1. Effects of early-life stress on corticosteroid binding globulins and albumin levels in serum and liver of adolescent rats.
    Authors:
    I. Majcher-Maślanka, A. Solarz, K. Wędzony, A. Chocyk
    Conference:
    11th International Regional (North America) Neuroscience and Biological Psychiatry Conference Stress and Behavior" (rok: 2017, ), Wydawca: International Stress and Behavior Society (ISBS)
    Data:
    konferencja 22-24 czerwiec
    Status:
    Published

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