Projects funded by the NCN

"The Role of Adipose Tissue and microRNA in the Progression of Clear Cell RenalCell Carcinoma".

Call: PRELUDIUM 24 , Panel: NZ4

Principal investigator: Dorota Małgorzata Kwapisz

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Next-Generation Exosome Therapy: Engineering NK Cell-Derived Vesicles for Targeted Cancer Treatment

Call: SONATINA 9 , Panel: NZ6

Principal investigator: dr Daria Nawrocka

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Reciprocal relationships in metastatic colorectal cancer and its niche – from adaptation to host organs to induced paren...

Call: OPUS 28 (LAP) , Panel: NZ2

Principal investigator: dr Michał Artur Bieńkowski

Gdański Uniwersytet Medyczny

Neutrophil Dynamics: Unveiling Anti-Tumor and Therapy Efficacy with the TUmor Neutrophil Immunotherapy on Chip (TUNIC) m...

Call: SONATA 20 , Panel: NZ6

Principal investigator: dr Martin Nurmik

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Canonical and non-canonical roles of DDK in oncogenesis: a cornerstone for the development of novel, potent anticancer t...

Call: SONATA BIS 14 , Panel: NZ3

Principal investigator: dr Jan Marian Suski

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Molecular factors and pathomechanism of cancer-associated cachexia.

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr hab. Marcin Tomasz Skrzypski

Gdański Uniwersytet Medyczny

(Lipid-FLUX) Single-cell lipidomics by spectroscopy: Quantification of the lipid transport through the development of ne...

Call: OPUS 27 , Panel: ST4

Principal investigator: prof. Małgorzata Anna Barańska

Uniwersytet Jagielloński

Precision double strike against non-small cell lung cancer. Insights into multidirectional therapies and the landscape o...

Call: OPUS 27 , Panel: NZ5

Principal investigator: dr Katarzyna Anna Malarz

Politechnika Śląska

Evaluation of the relationship between doxorubicin resistance, epithelial-mesenchymal plasticity, and effects of selecte...

Call: PRELUDIUM 23 , Panel: NZ5

Principal investigator: Dominika Kunachowicz

Uniwersytet Medyczny im. Piastów Śląskich we Wrocławiu, Wydział Farmaceutyczny z Oddziałem Analiutyki Medycznej

Defining the transcriptional and epigenetic state of tumor cells with increased plasticity and the epithelial-endothelia...

Call: OPUS 26 , Panel: NZ5

Principal investigator: dr hab. Agnieszka Kobielak

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

Targeting adenylate kinase 4 (AK4) as a new paradigm in the treatment of non-small cell lung cancer: discovery and evalu...

Call: OPUS 26 , Panel: NZ7

Principal investigator: dr Magdalena Wujak

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy

Design and characterisation of sealing materials of prosthetic obturator being additionally a cytostatic drug reservoir....

Call: OPUS 26 , Panel: ST8

Principal investigator: prof. Anna Trusek

Politechnika Wrocławska

How is meiotic TEX12 re-activated in cancer and can we exploit this in the clinic?

Call: SONATA BIS 13 , Panel: NZ3

Principal investigator: dr Urszula Łucja Mcclurg

Instytut Biologii Medycznej PAN

Investigating mechanisms regulating ALCAM alternative splicing and susceptibility of this molecule to cleavage by shedda...

Call: OPUS 25 , Panel: NZ2

Principal investigator: dr Marta Karolina Wagner

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Quantitation of metabolic turnover in single cancer cells by infrared microscopy

Call: OPUS 25 , Panel: NZ1

Principal investigator: dr Luca Quaroni

Uniwersytet Jagielloński, Wydział Chemii

INVADOPODIA IN AXL-DRIVEN CANCER INVASION AND DRUG RESISTANCE

Call: OPUS 25 , Panel: NZ3

Principal investigator: dr Daria Paulina Zdżalik-Bielecka

Uniwersytet Warszawski, Wydział Biologii

Targeting Energy Metabolism for Precision Cancer Therapy: Novel Inhibitors of LDH-A and PDK1 as Potential Strategies to ...

Call: PRELUDIUM 22 , Panel: NZ7

Principal investigator: Marika Anna Frańczak

Gdański Uniwersytet Medyczny, Wydział Lekarski

Myeloid cell subpopulations as a source of effector cells for anticancer therapies using CAR chimeric receptors

Call: OPUS 25 , Panel: NZ6

Principal investigator: dr hab. Angelika Muchowicz

Warszawski Uniwersytet Medyczny, Wydział Lekarski

Elucidation of the role of ERM and merlin proteins in the process of formation of entotic structures and identification ...

Call: PRELUDIUM 22 , Panel: NZ3

Principal investigator: Agata Maria Gaweł

Warszawski Uniwersytet Medyczny

Ultrasensitive profiling of mutations driving tumorigenesis in hereditary syndromes associated with tumor suppressor gen...

Call: OPUS 25 , Panel: NZ5

Principal investigator: dr Katarzyna Klonowska

Instytut Chemii Bioorganicznej PAN

Spatial Determinants of Immunotherapy Resistance in Cancer

Call: WEAVE-UNISONO , Panel: NZ6

Principal investigator: dr Marcin Tabaka

Instytut Chemii Fizycznej Polskiej Akademii Nauk, Międzynarodowe Centrum Badań Oka

Precise molecular characterization of circulating tumour cells in patients with triple negative breast cancer using high...

Call: OPUS 24 , Panel: NZ7

Principal investigator: prof. Stefano Volinia

Uniwersytet Warszawski, Centrum Nauk Biologiczno-Chemicznych

Circadian signaling functions of the phosphoinositide phosphatase SHIP2

Call: SONATA BIS 12 , Panel: NZ3

Principal investigator: dr Abdelhalim Azzi

Międzynarodowy Instytut Mechanizmów i Maszyn Molekularnych Polskiej Akademii Nauk

Histone demethylase inhibitors as chemosensitivity modulators in the treatment of head and neck squamous cell carcinoma

Call: PRELUDIUM 21 , Panel: NZ7

Principal investigator: Dawid Dariusz Dorna

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

The role of 5-methylcytosine RNA methyltransferases in the regulation of cancer cell responses to extracellular and exog...

Call: OPUS 22 , Panel: NZ2

Principal investigator: dr hab. Anna Karolina Lewińska

Uniwersytet Rzeszowski, Collegium Medicum Wydział Biotechnologii

Combinatorial targeting of non-genetic sources of cell-to-cell heterogeneity to overcome fractional killing of cancer ce...

Call: SONATA 17 , Panel: NZ3

Principal investigator: dr Jarosław Walczak

Instytut Podstawowych Problemów Techniki Polska Akademia Nauk

In vitro tracing of cellular senescence to cancer stem cell formation using a nanoparticle-based reporter system

Call: OPUS 22 , Panel: NZ3

Principal investigator: dr Patrick McDevitt Perrigue

Uniwersytet im. Adama Mickiewicza w Poznaniu, Centrum NanoBioMedyczne

New strategies in the treatment of non-small cell lung cancer based on silk nanocarriers targeting tumor vascularization

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Anna Katarzyna Florczak-Substyk

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Light-producing, oxygen-delivering, cancer cell-targeted carriers for photosensitisers dedicated for photodynamic therap...

Call: OPUS 22 , Panel: NZ7

Principal investigator: prof. Marek Arkadiusz Murias

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Targeting cell surface proteoglycans with high affinity multimeric ligands and their cytotoxic conjugates – towards prec...

Call: OPUS 22 , Panel: NZ1

Principal investigator: dr hab. Łukasz Opaliński

Uniwersytet Wrocławski, Wydział Biotechnologii

Identification of the adipogenic niche derived molecules as the factors driving the colorectal cancer cell progression

Call: OPUS 22 , Panel: NZ3

Principal investigator: dr hab. Dorota Nowak

Uniwersytet Wrocławski, Wydział Biotechnologii

The interplay of neurochemistry and cancer biology: in the search for novel glioblastoma multiforme therapy among dopami...

Call: SONATA 17 , Panel: NZ7

Principal investigator: dr Katarzyna Maria Kucwaj-Brysz

Uniwersytet Jagielloński, Collegium Medicum

RE-SENSE: Dual-loaded lipid nanoparticles to overcome the resistance of non-small cell lung cancer cells to personalized...

Call: PRELUDIUM 20 , Panel: NZ7

Principal investigator: Mikołaj Czajkowski

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu

Evaluation of NOTCH1- and NOTCH3-dependent anticancer drug resistance in a 2D and 3D model of Head and Neck Squamous Cel...

Call: PRELUDIUM 20 , Panel: NZ5

Principal investigator: dr Joanna Elżbieta Kałafut

Uniwersytet Medyczny w Lublinie

The clinical significance of immunosuppression in ovarian cancer microenvironments

Call: PRELUDIUM 20 , Panel: NZ6

Principal investigator: dr Anna Maria Pawłowska-Łachut

Uniwersytet Medyczny w Lublinie

Reversible senescence as a new mechanism of cancer cell resistance for chemotherapy. Analysis of the mechanism of cancer...

Call: SONATINA 5 , Panel: NZ3

Principal investigator: dr Karolina Anna Staniak

Politechnika Warszawska, Wydział Chemiczny

Influence of indyvidual low-dose radiosensitivity on the chemopotentiating effect of low-dose fractionated radiation in ...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: dr hab. Dorota Słonina

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie, Oddział w Gliwicach

MicroRNAome maturation control and its application in selective targeting of cancer stem cells

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Jakub Godlewski

Instytut Medycyny Doświadczalnej i Klinicznej im. Mirosława Mossakowskiego PAN

AXL receptor signaling in cancer cell growth and drug resistance

Call: OPUS 20 , Panel: NZ3

Principal investigator: prof. Marta Elżbieta Miączyńska

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

Towards re-definition of the mechanisms of entotic cell death; the role of HAX1 and SEPT7 in the regulation of entosis i...

Call: OPUS 20 , Panel: NZ3

Principal investigator: dr hab. Ewa Anna Grzybowska

Centrum Onkologii - Instytut im. Marii Skłodowskiej-Curie

Phylogenetic models to infer cancer evolution

Call: SONATA 16 , Panel: ST6

Principal investigator: dr Jarosław Andrzej Paszek

Uniwersytet Warszawski, Wydział Matematyki, Informatyki i Mechaniki

Genomic profiling of circulating biomarkers and matched primary tumors from breast cancer patients

Call: OPUS 20 (LAP) , Panel: NZ5

Principal investigator: dr Aleksandra Markiewicz

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Meaning-reconstruction process in cancer: the role of psychological flexibility. Intensive longitudinal and experimental...

Call: OPUS 20 , Panel: HS6

Principal investigator: dr hab. Aleksandra Karolina Kroemeke

Szkoła Wyższa Psychologii Społecznej w Warszawie

Identification of potential markers aiming early diagnostics of progression and tailoring metastasis-oriented therapies ...

Call: OPUS 20 , Panel: NZ5

Principal investigator: dr Natalia Bednarz-Knoll

Gdański Uniwersytet Medyczny, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Comprehensive characterization of tumor immune contexture changes induced by cytotoxic agents in non-small cell lung can...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: prof. Wojciech Maksymilian Fendler

Uniwersytet Medyczny w Łodzi

Usefulness of liquid biopsy" in diagnostics, stratification, and monitoring of therapy in non-small cell lung cancer pat...

Call: PRELUDIUM BIS 2 , Panel: NZ5

Principal investigator: dr hab. Joanna Natalia Budna-Tukan

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

A tissue engineering platform for precision cancer medicine and chemosensitivity testing in head and neck squamous cell ...

Call: OPUS 19 , Panel: NZ4

Principal investigator: prof. Matthias Nees

Uniwersytet Medyczny w Lublinie

Regulation of Serpine1 expression in kidney cancer - role of hypoxia

Call: PRELUDIUM 19 , Panel: NZ5

Principal investigator: Aleksandra Martyna Majewska

Wojskowy Instytut Medyczny

Early Detection and surveillance of Esophageal cancer with the Cytosponge™ and Nucleic acid biomarkers (the EDEN study)...

Call: OPUS 19 , Panel: NZ5

Principal investigator: Władysław Januszewicz

CENTRUM MEDYCZNE KSZTAŁCENIA PODYPLOMOWEGO

Increasing the precision of chimeric antigen receptor (CAR)-mediated anticancer immunotherapy by using the chemokine-ind...

Call: OPUS 19 , Panel: NZ6

Principal investigator: dr hab. Radosław Zagożdżon

Warszawski Uniwersytet Medyczny