Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Mechanism regulating vitamin D analog cooperation with cytostatics and tyrosine kinase inhibitors in non-small cell lung cancer model

2013/09/N/NZ4/01720

Keywords:

PRI-2191 analog tyrosine kinase inhibitors NSCLC

Descriptors:

  • NZ5_7: Human disease treatment
  • NZ3_3: Apoptosis
  • NZ4_12: Other related subjects

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ewa Maj 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2014-03-04

Project end date (Y-m-d): 2017-07-03

Project duration:: 40 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Antiangiogenic cancer treatment: the great discovery and greater complexity (Review)
    Authors:
    Ewa Maj, Diana Papiernik, Joanna Wietrzyk
    Academic press:
    International Journal of Oncology (rok: 2016, tom: 49, strony: 1773-1784), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10. - link to the publication
  2. Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model
    Authors:
    Ewa Maj, Beata Filip-Psurska, Marta Świtalska, Andrzej Kutner, Joanna Wietrzyk
    Academic press:
    International Journal of Molecular Sciences (rok: 2015, tom: 16, strony: 27191-27207), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms161126016 - link to the publication
  1. Antiangiogenic treatment in non-small cell lung cancer (NSCLC)
    Authors:
    Maj Ewa
    Conference:
    3rd International Conference on Integrative Biology (rok: 2015, ), Wydawca: OMICS International
    Data:
    konferencja 04-06.08.2015
    Status:
    Published
    DOI:
    link to the publication
  2. The correlation between p53 and VEGF-A expression in A549 lung cancer cells after treatment with sunitinib combined with cytostatics and vitamin D analog PRI-2191
    Authors:
    Maj E., Kłopotowska D., Kutner A., Wietrzyk J.
    Conference:
    43rd Winter School of Faculty of Biochemistry, Biophysics and Biotechnology "Biomolecules: from structure to function" (rok: 2016, ), Wydawca: Faculty of Biochemistry, Biophysics and Biotechnology Jagiellonian University
    Data:
    konferencja 16-20.02.2016
    Status:
    Published
  3. Sunitinib with docetaxel up-regulate p53 pathway in A549 lung cancer cells resulting in down-regulation of VEGF-A secretion
    Authors:
    Maj E., Wietrzyk J.
    Conference:
    42nd Winter School of Faculty of Biochemistry, Biophysics and Biotechnology From Genome to Proteome" (rok: 2015, ), Wydawca: Faculty of Biochemistry, Biophysics and Biotechnology Jagiellonian University
    Data:
    konferencja 10-14.02.2015
    Status:
    Published

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