Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role of estrogens in epigenetic regulation of hypoxia-related gene expression in non-small cell lung cancer development

2013/11/B/NZ5/00039

Keywords:

non-small cell lung cancer,estrogens 17β-estradiol epigenetics hypoxia normoxia

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Medyczny

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Paweł Jagodziński 

Number of co-investigators in the project: 10

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 931 627 PLN

Project start date (Y-m-d): 2014-07-22

Project end date (Y-m-d): 2020-01-21

Project duration:: 66 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Inkubator CO2 z płaszczem wodnym Forma* Series II 3110 (70 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (1)
  1. Altered expression of 17-beta-hydroxysteroid dehydrogenase type 2 and its prognostic significance in non-small cell lung cancer
    Authors:
    Hanna Drzewiecka, Donata Jarmołowska-Jurczyszyn, Andrzej Kluk, Bartłomiej Gałęcki, Wojciech Dyszkiewicz, Paweł P. Jagodziński
    Academic press:
    International Journal of Oncology (rok: 2020, tom: 56, strony: 1352-1372), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijo.2020.5014 - link to the publication
  2. Increased expression of proline-, glutamic acid- and leucine-rich protein PELP1 in non-small cell lung cancer
    Authors:
    Słowikowski BK, Gałęcki B, Dyszkiewicz W, Jagodziński PP
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2015, tom: 73, strony: 97-101), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2015.05.015 - link to the publication
  3. Decreased expression of connective tissue growth factor in non-small cell lung cancer is associated with clinicopathological variables and can be restored by epigenetic modifiers
    Authors:
    Hanna Drzewiecka, Bartłomiej Gałęcki, Donata Jarmołowska-Jurczyszyn, Andrzej Kluk, Wojciech Dyszkiewicz, Paweł P. Jagodziński
    Academic press:
    Journal of Cancer Research and Clinical Oncology (rok: 2016, tom: 142, strony: 1927-1946), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00432-016-2195-3 - link to the publication
  4. Increased expression of 17-beta-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer
    Authors:
    Drzewiecka H, Gałęcki B, Jarmołowska-Jurczyszyn D, Kluk A, Dyszkiewicz W, Jagodziński PP
    Academic press:
    Lung Cancer (rok: 2015, tom: 87, strony: 107-116), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.lungcan.2014.12.012 - link to the publication
  1. Expression of 17-beta-hydroxysteroid dehydrogenase type 1 and type 2 in non-small cell lung cancer
    Authors:
    Hanna Drzewiecka, Bartłomiej Gałęcki, Wojciech Dyszkiewicz, Paweł P. Jagodziński.
    Conference:
    26th Bilateral Symposium Poznan-Halle "From Molecular Medicine to Public Health - Translational Research in Cardiovascular Medicine and Oncology" (rok: 2015, ), Wydawca: MARTIN LUTHER UNIVERSITY HALLE−WITTENBERG
    Data:
    konferencja 23-25 październik
    Status:
    Published

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